May 2013
Emily Chen
Thesis Title: "ERM proteins in T cell adhesion and migration"
Thesis Advisor: Jan Burkhardt, Ph.D.
Natalia Ramos Hernandez
Thesis Title: "The role of NDFIP1 in T cell tolerance"
Thesis Advisor: Paula Oliver, Ph.D.
Natalie Steinel
Thesis Title: "Multiple mechanisms cooperate to enforce antigen receptor allelic exclusion"
Thesis Advisor: Craig Bassing, Ph.D.
December 2012
Jill Angelosanto
Thesis Title: “Progressive loss of memory T cell potential and commitment to exhaustion during chronic viral infection”
Thesis Advisor: John Wherry, Ph.D.
Evann Corbo-Rodgers
Thesis Title: “The role of SLP-76 in the homeostasis of CD4+ T cells”
Thesis Advisor: Jonathan Maltzman, M.D., Ph.D.
Ji-Yeon Kim
Thesis Title: “Development and regulation of natural T helper 17 cells”
Thesis Advisor: Gary Koretzky, M.D., Ph.D.
Rebecca May
Thesis Title: “Proximal signaling pathways in natural killer cell development and effector function”
Thesis Advisors: Gary Koretzky, M.D., Ph.D., Taku Kambayashi, M.D., Ph.D.
Michael Paley
Thesis Title: “Transcriptional control and population dynamics of antiviral CD8+ T cell responses”
Thesis Advisor: John Wherry, Ph.D.
Shruti Naik
Thesis Title: “Host-commensal cross talk at the cutaneous interface”
Thesis Advisor: Yasmine Belkaid, Ph.D.
August 2012
Michael Abt
Thesis Title: “Commensal bacterial communities regulate antiviral immunities”
Thesis Advisor: John Wherry, Ph.D.
Alexandra Bortnick
Thesis Title: “The formation and maintenance of long-lived plasma cells in T-independent and T-dependent immune responses"
Thesis Advisor: David Allman, Ph.D.
May 2012
Danielle Haney
Thesis Title: “Impact of HAART in T cell activation in HIV-infected adolescents”
Thesis Advisor: Michael R. Betts, Ph.D.
Brittany Weber
Thesis Title: “Defining the role of T cell factor 1 (TCF-1) in T-lineage development and differentiation”
Thesis Advisor: Avinash Bhandoola, M.B., B.S., Ph.D
Tao Zhou
Thesis Title: “Signals controlling regulatory t cell differentiation and homeostasis”
Thesis Advisor: Gary Koretzky, M.D., Ph.D.
December 2011
Scott Gordon
Thesis Title: “Development of natural killer cells regulated by T-box transcription factors”
Thesis Advisor: Steven L. Reiner, M.D.
Jonathan Silver
Thesis Title: “The role of IL-6 in regulating innate and adaptive immunity”
Thesis Advisor: Christopher A. Hunter, Ph.D.
Greg Sonnenberg
Thesis Title: “Interleukin-22 regulates immunity, inflammation and tissue homeostasis at mucosal sites”
Thesis Advisor: David Artis, Ph.D.
Anastasia Tikohonova
Thesis Title: “Generation and characterization of αβ TCRs that recognize MHC-independent ligands”
Thesis Advisor: Alfred Singer, M.D.
August 2011
Keri Beth Sanborn
Thesis Title: “Role and regulation of myosin IIA in natural killer cell cytotoxicity”
Thesis Advisor: Jordan S. Orange, M.D., Ph.D.
May 2011
Brenna Brady
Thesis Title: "Regulation of TCRβ accessibility and αβ T cell development in response to V(D)J recombination mediated signals"
Thesis Advisor: Craig H. Bassing, Ph.D.
Anthony Chi
Thesis Title: "Delineation of the Cellular Pathway and Molecular Mechanisms of Notch1-Mediated Early T Lineage Development"
Thesis Advisor: Avinash Bhandoola M.B.B.S., Ph.D.
Dan Zlotoff
Thesis Title: "Signals Governing the Recruitment of T Lineage Progenitors to the Thymus"
Thesis Advisor: Avinash Bhandoola M.B.B.S., Ph.D.
December 2010
Jason Hall
Thesis Title: "Vitamin A and commensal stimulation in the generation of mucosal immunity"
Thesis Advisor: Yasmine Belkaid, Ph.D.
Hilda Ramon
Thesis Title: “The role of NDFIP1 in the regulation of T cell-mediated inflammation at mucosal barrier”
Thesis Advisor: Paula M. Oliver, Ph.D.
Jennifer Reed
Thesis Title: “Examination of the role of plasma membrane cholesterol in B cell development"
Thesis Advisor: John Monroe, Ph.D.
Marta Rowh
Thesis Title: “DNA damage responses and suppression of chromosomal translocationsin developing lymphocyte"
Thesis Advisor: Craig Bassing, Ph.D.
Will Quinn
Thesis Title: “Mechanisms governing plasma cell differentiation and longevity”
Thesis Advisor: Michael P. Cancro, Ph.D.
August 2010
Soyoung Oh
Thesis Title: "The effect of T cell receptor specificity on CD4+CD25+ regulatory T cell function in an autoimmune setting"
Thesis Advisor: Andy Caton, Ph.D.
Jennifer Smith
Thesis Title: “The role of SLP-76 phosphotyrosines in TCR signal transduction and T cell differentiation”
Thesis Advisor: Gary Koretzky, M.D., Ph.D.
Greta Weiss
Thesis Title: “The acquisition of human B cell memory in response to Plasmodium falciparum malaria”
Thesis Advisor: Susan K. Pierce, Ph.D.
May 2010
Tony Barnitz
Thesis Title: "An Analysis of Cell Death and Cell Cycle Arrest During Human Immunodeficiency Virus Type 1 Infection"
Thesis Advisor: Michael Lenardo, M.D.
Marco Calamito
Thesis Title: "Characterization of B cell development and activation in the absence of Akt or Presenilin"
Thesis Advisor: Dave Allman, Ph.D.
Kim Jordan
Thesis Title: "Regulation of CD8+ T Cell Responses to Toxoplasma gondii"
Thesis Advisor: Christopher Hunter, Ph.D.
Michelle Kinder
Thesis Title: "Fatty acid metabolism mediated by 12/15-lipoxygenase is a novel regulator of hematopoietic stem cell function and myelopoiesis"
Thesis Advisor: Ellen Pure, Ph.D.
Jack Treml
Thesis Title: "Role of Pim Kinases in the Humoral Immune Response"
Thesis Advisor: Mike Cancro, Ph.D.
December 2009
Esteban Carrizosa
Thesis Title: "Role and Regulation of the actin-regulatory protein HS1 in TCR signaling"
Thesis Advisor: Jan Burkhardt. Ph.D.
Jacqueline Perrigoue
Thesis Title: "Initiation and regulation of type 2 immunity and inflammation at mucosal sites "
Thesis Advisor: David Artis, Ph.D.
Adeeb Rahman
Thesis Title: "Defining a T cell intrinsic role for MyD88 during LCMV infection"
Thesis Advisor: Laurence Turka, M.D.
Betsy Taylor
Thesis Title: "TSLP regulates intestinal immunity and inflammation"
Thesis Advisor: David Artis, Ph.D.
August 2009
Thi Bui
Thesis Title: "Regulation of metabolism during proliferation and cellular stress"
Thesis Advisor: Craig Thompson, M.D.
Priya Dedhia
Thesis Title: "Tribbles in myeloid differentiation and transformation"
Thesis Advisor: Warren Pear, M.D., Ph.D.
Haina Shin
Thesis Title: "Regulation of CD8 T cell dysfunction during chronic viral infection"
Thesis Advisor: John Wherry, Ph.D.
May 2009
Andrea Carpenter
Thesis Title: “The TCRb LOCI: Mechanisms controlling rearrangement and allelic exclusion”
Thesis Advisor: Craig Bassing, Ph.D.
Erica Carpenter
Thesis Title: “Lymphocyte response and dysregulation in human cancer”
Thesis Advisor: Robert Vonderheide, M.D.
Sara Colpitts
Thesis Title: “The generation and maintenance of CD4+ T cell responses in concomitant immunity to Leishmania Major”
Thesis Advisor: Phillip Scott, Ph.D.
December 2008
Eric Allenspach
Thesis Title: “The role of dendritic cell subsets in the regulation of CD4+T cell responses"
Thesis Advisor: Terri Laufer, M.D.
Shannon Grande
Thesis Title: "A role for immunoreceptor tyrosine-based activation motifs in the transformation of nonhematopoietic cells"
Thesis Advisor: John Monroe, Ph.D.
Marisa Juntilla
Thesis Title: “Akt signaling maintains survival and proliferation in immature T cells and hematopoietic stem cells”
Thesis Advisor: Gary Koretzky, M.D., Ph.D.
Dan Northrup
Thesis Title: “The transcription factor EBF directs B lineage commitment”
Thesis Advisor: David Allman, Ph.D.
Paige Porrett
Thesis Title: “The subversion of treg-mediated transplantation tolerance by toll-like receptor signals”
Thesis Advisor: Laurence Turka, M.D.
Laura Solt
Thesis Title: “The interaction with NEMO regulations the function of Ikkalpha”
Thesis Advisor: Michael May, Ph.D.
Jason Standanlick
Thesis Title: “Tonic B cell antigen receptor signals supply an NF-kB substrate, p100, for prosurvival BLYS signaling”
Thesis Advisor: Michael Cancro, Ph.D.
Laura Treml
Thesis Title: “Role for TACI, a BLYS receptor, in toll-like receptor stimulated B cells and marginal zone fitness”
Thesis Advisor: Michael Cancro, Ph.D.
Matt Walsh
Thesis Title: “The role of the adaptor protein TRAF6 in CD8 T cell homeostasis and as a substrate for non-degradative ubiquitination”
Thesis Advisor: Yongwon Choi , Ph.D.
August 2008
Stanley Adoro
Thesis Title: “Regulation of Coreceptor Gene Transcription and CD4/CD8 Lineage Choice in the Thymus”
Thesis Advisor: Alfred Singer, M.D.
Jenni Crowley
Thesis Title: “BLYS receptor regulation and responsiveness in activated B lymphocytes”
Thesis Advisor: Michael Cancro, Ph.D.
Alice Hsu
Thesis Title: “Impaired immune activation following Leishmania Mexicana infection”
Thesis Advisor: Phillip Scott, Ph.D.
Frederick Karnell
Thesis Title: “Developmental-associated differences in membrane cholesterol content play a defining role in the response of transitional immature and mature B cells to B cell receptor engagement”
Thesis Advisor: John Monroe, Ph.D.
Jodi Karnell
Thesis Title: “Regulation of CD4+ T cell responses by PTEN”
Thesis Advisor: Laurence Turka, M.D.
Vikram Palanivel
Thesis Title: “ The role of an asymmetric T lymphocyte division in generating diversity during adaptive immune responses”
Thesis Advisor: Steven Reiner, M.D.
Megan Suhoski
Thesis Title: “Optimal activation, growth and expansion of Human CD8+ T cells using a novel artificial antigen presenting cell system”
Thesis Advisor: Carl June, M.D.
Justin Taylor
Thesis Title: “Immunoregulation of helminith-induced Th2 responses”
Thesis Advisor: Edward Pearce, Ph.D.