Search for Faculty by Name or Research Interest:
Role of regulatory T cells during infections.
Genetic analysis of intrathymic T-cell development
Caspi, Rachel, Ph.D.
Self-tolerance and autoimmunity with a focus on immunologically privileged retinal antigens.
Analysis of T cell immune responses in humans in order to develop strategies to amplify, broaden or focus T cell immunity to HIV infection, vaccine development
Garboczi, David N., Ph.D.
Structural Biology of membrane proteins and the T-Cell Receptor.
Germain, Ronald, M.D., Ph.D.
Peptide complexes with MHC molecules; self-peptide:MHC molecule recognition in development of thymic T cells; biochemical mechanisms of TCR discrimination between self and foreign peptide associated MHC molecules
Lenardo, Michael, M.D.
Programmed cell death in immunological tolerance, autoimmunity, and viral pathogenesis by HIV
Cytokine signal transduction and the molecular basis of immunoregulation
Paul, William E., M.D.
Mechanisms of action of type I cytokines, principally IL-4, the biologic functions of these cytokines and the differentiation of naive T cells into cytokine-producing and memory cells.
B cell signaling, vaccine development, malaria
Signal Transduction Events Mediated by the T Cell Antigen Receptor
Development of vaccines for infectious diseases; cellular and molecular mechanisms by which various cytokines and costimulatory molecules regulate cellular immunity in vivo
Schwartzberg, Pamela, M.D., Ph.D.
Signal transduction pathways involving cytoplasmic tyrosine kinases, and how defects in these pathways contribute to disease processes.
Sher, Alan, Ph.D.
Immune regulation in parasitic and bacterial infections.
Siegel, Richard, M.D., Ph.D.
TNF-receptor family signaling in normal and pathological immune responses, with emphases on the cell biology of receptor signaling, transgenic mouse models, and crosstalk between cell-death and survival signals.
Singer, Alfred, M.D.
Lymphocyte recognition and development, especially the molecular and cellular recognition signals that result in self/non-self discrimination during thymic development.
Staudt, Louis, M.D., Ph.D.
Molecular pathogenesis of human leukemias, BCL-6 oncogene in large-cell lymphoma, micro-arrays of gene expression in human lymphomas and leukemias
Sun, Peter, Ph.D.
Structural Biology of NK cell receptors and TGF-ß receptors.
Waldmann, Thomas A., M.D.
The critical role of IL-2R and related receptors on the growth and differentiation of normal and neoplastic T-cells with a particular emphasis on IL-15 and IL-15 receptors.