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CAR T-cell Studies Led to First-ever Cell and Gene Therapy Approval

In a landmark decision for the field of cancer immunotherapy, the U.S. Food and Drug Administration (FDA) today approved a personalized cellular therapy developed by the University of Pennsylvania and Children’s Hospital of Philadelphia (CHOP)...More

Cancer Cells Force Normal Cells to Mimic Viruses to Help Tumors Spread, Resist Treatment

Andy Minn, PhD and his lab publish a study that could explain why some breast cancers are more aggressive than others...More

CAR T-cell Treat considered for FDA Approval

In the Washington Post: "An FDA advisory committee will decide Wednesday whether to recommend approval of the approach"...More

Penn Bioengineering's Dongeun Huh Receives Technology Impact Award

Dongeun Huh, PhD received the Cancer Research Institute's Technology Impact Award for his work on microchip-based research models of human cancer and immune cell interactions. John Wherry, PhD and G. Scott Worthen, MD are collaborating with Dr. Huh...More

MD/PhD Student Jae Lee on Mouse Models of Pancreatice Cancer

In Currrent Protocols in Pharmacology: "Pancreatic ductal adenocarcinoma (PDAC) ranks fourth among cancer-related deaths in the United States and for patients with unresectable disease, treatment options are currently limited and lack curative potential"...More

A Perturbed Skin Microbiome Can Be ‘Contagious’ and Promote Inflammation

According to the Grice and Scott Labs, not only can infection with the Leishmania parasite alter the skin microbiome of affected mice, but this altered microbial community can be passed to uninfected mice that share a cage with the infected animals...More

Lenardo Lab Investigates CD55 Deficiency and Early-Onset Protein-Losing Enteropathy

NIH/Penn faculty member Michael Lenardo, MD, PhD and his lab present their current research in the New England Journal of Medicine...More

Jorge Henao-Mejia Selected as Pew Scholar

Jorge Henao-Mejia, MD, PhD has been selected as one of 22 national Pew Scholars in Biomedical Sciences...More

Scott Hensley Talks with Channel 6 ABC News About Influenza Research

Dr. Scott Hensley is interviewed by WPVI-TV/Channel 6 ABC Action News about his recent work on the influenza virus...More

López Lab Publishes Work on Immune Response to Respiratory Syncytial Virus

Faculty member Carolina López, PhD and members of her lab recently published their work on respiratory syncytial virus (RSV) in PLOS Pathogens. In this paper, Dr. López and her lab describe a subset of viral products that elicit a strong immune response against RSV in people who become infected...More

Graduate Drew Comrie Receives CHOP Research Award

Recent Graduate Drew Comrie received the 2015 CHOP Distinguished Research Trainee Awards for his outstanding work on T cell mechanics under the supervision of Janis Burkhardt, PhD...More

Raj Lab's Work Explores Cell Size and DNA Content

Bioengineering faculty Arjun Raj and his lab address the question of cell volume variability amongst cell with the same function and DNA...More

T Cell Exhaustion and the PD-1 Protein Pathway

A new paper in the Journal of Experimental Medicine from John Wherry's Lab presents data showing that PD-1 may not be the cause of T cell exhaustion...More

Scott Lab Studies Immune Response to Leishmaniasis

Phillip Scott's Lab work on leishmaniasis is highlighted in the latest Penn Current issue...More

IGG Faculty Awarded $7.5 Million for HIV Gene Therapy Research

James Riley, PhD, James Hoxie, MD, John Wherry, PhD, Frederic Bushman, PhD, and Pablo Tebas, MD have been awarded $7.5 million from the NIH to begin work on a new gene therapy addressing HIV...More

Ellen De Obaldia Receives IGG Award for Outstanding Dissertation

Maria Elena (Ellen) De Obaldia this year's winner of the IGG Saul Winegrad Award for Outstanding Dissertation. Ellen completed her dissertation, "T-Lineage Specification and Commitment Requires Constraint of Myeloid Gene Expression Programs by HES1", under the supervision of Avinash Bhandoola; currently, she is a postdoctoral fellow in the Vosshall Laboratory at The Rockefeller University. She will be recognized at the Biomedical Graduate Studies Graduation and Hooding Ceremony on May 18.

David Allman Recognized for Teaching

David Allman, PhD recieved this year's Dean's Award for Excellence in Basic Science Teaching in recognition of his outstanding medical school teaching...More

CFAR Faculty Receive Award for HIV Research

Carl June, MD, Bruce Levine, PhD, and Pablo Teblas, MD were among those who received the 2015 Clinical Research Achievement Award by the Clinical Research Form for their work on gene editing of CCR5 in HIV patients...More

Metastatic Melanoma Patients Respond to New Combination of Immunotherapy Drugs

New IGG faculty member Jorge Ivan Alvarez’s recent work with Cornelia Podjaski of McGill University appears in the latest edition of Brain...More

David Weiner-led Group Awarded $16 Million NIH Award to Develop DNA Vaccines to Fight HIV

David Weiner, PhD is the principal investigator on an NIAID grant to develop synthetic HIV antigens...More

Kristen Lynch Publishes Work on Alternative Splicing and T-cell Signaling

A new study by Kristen Lynch's lab shows that the expression of CELF2, anRNA binding protein, increased in response to T-cell stimulation...More

Metastatic Melanoma Patients Respond to New Combination of Immunotherapy Drugs

David Bajor and Robert Vonderheide presented the results of their recent study on a new combination of immunotherapy drugs at the 2015 AACR Annual Meeting...More

David Weiner and Lab Recognized for Vaccine Research

David Weiner, PhD and his research team were awarded the 2015 Vaccine Industry Excellence Award at a recent meeting of the World Vaccine Congress...More

Amanda Schmidt on Regulatory T Cells and TCR Signaling

Recent IGG graduate Amanda Schmidt published her research in a recent issue of The Journal of Immunology, "Regulatory T Cells Require TCR Signaling for Their Suppressive Function"...More

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