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Computational Neuroscience

How does the brain compute? This is a fundamental question of neuroscience -- it's related to every function of the brain, since almost all tasks require computation. Imagine the many computations required to move your hand and grasp an object...or parse a visual scene into objects.

The computational approach to neuroscience involves computer simulations and modeling, and the goals are generally one or more of the following: 1) to conduct in silico tests of ideas and hypotheses; 2) to get a better understanding of experimental data, particularly data coming from diverse methodologies; and 3) to generate new and testable hypotheses to guide future experiments.

 

Labs at Penn that have computational neuroscience projects:

Benjamin T. Backus, PhD   Psychophysics; computational modeling; evoked potentials, fMRI

David H Brainard, PhD    Visual perception and its neural mechanisms; digital image processing.

Gershon Buchsbaum, PhD     Visual signal processing and image coding, modeling of retinal and visual system architecture and function, computational neuroscience and neural networks

Nader Engheta, PhD     Biologically inspired polarization imaging and applications, electromagnetics, optics

Nabil H. Farhat, PhD     The focus of my research is in Corticonics where I am applying concepts and tools from nonlinear dynamics, bifurcation theory, self-organized criticality, complexity, and chaos to the modeling and study of the cortex. In corticonics (echoing electronics) I am concerned with developing a dynamical approach to understanding the cortex and its collective codes for information processing.

George L. Gerstein, PhD     Representationof information in auditory and visual systems, particularly with reference to function of assemblies of neurons; models of neuronal networks

Joshua Gold, PhD    How the brain forms decisions about sensory stimuli: What are the underlying neural computations? Where are the circuits that perform these computations? How are these circuits shaped by experience?

Alan Gottschalk, MD/PhD     Theory of neural information processing and control; self-organization and adaptation of networks which perform information processing and control; nonlinear dynamics of neural systems; quantification of the clinical correlates of these processes

Michael J. Kahana, PhD     Human memory and its neural mechanisms; Brain Oscillations

Max B. Kelz, MD, PhD   EEG/EMG study of behavioral state including spectral analysis and chaos theory entropy analysis

Daniel D. Lee, PhD    Computational neuroscience machine learning, biologically-inspired artificial sensorimotor systems

Richard Murray, PhD    Visual psychophysics, spatial vision, perceptual organization, visual attention; natural image statistics in relation to shape from shading and perceptual organization; signal detection theory, ideal decision theory, multiple spatial frequency channel theory

Robert G. Smith, PhD     Understanding how the structure and biophysical properties of a neuron influence the signal processing function of the surrounding neural circuit

Santosh S. Venkatesh, PhD     Neural networks; statistical pattern recognition; computational learning theory; information and complexity theory

 



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