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Thomas D. Parsons, V.M.D., Ph.D.
Associate Professor of Swine Production Medicine, Dept of Clinical Science
New Bolton Center School
of Veterinary Medicine
610-444-5800 ext 2554
FAX: 610-925-8123
email: thd@vet.upenn.edu
Click here for selected publications since Dr. Parsons' arrival at Penn
RESEARCH INTERESTS
Cellular and molecular mechanisms of neurotransmitter releaseRESEARCH TECHNIQUES
time-resolved detection of neurotransmitter release from single cells: cell membrane capacitance, amperometric voltametry, and voltage clamp of detector cells or sniffer patches; optical monitoring and modulation of intracellular calcium; fluorescent indicator dyes of calcium, and photolabile chelators of calcium; cell culture and brain slice-like preparations.RESEARCH SUMMARY
My laboratory focuses on pre-synaptic mechanisms of neurotransmitter release.
Hearing dictates that the inner hair cell of the cochlea must release transmitter
for prolonged periods and with exquisite temporal fidelity. Mechanisms of
neurotransmitter release are being studied to understand the cellular and
molecular specializations utilized by different parts of the nervous system
to meet their unique requirements for neurotransmission.
KEY WORDS:
exocytosis, endocytosis, synaptic transmission, neurotransmitter release
