Kinetic Modeling and Simulation ( KMAS ) core will provide crucial infrastructure to the growing translational effort at the partner institutions of the University of Pennsylvania and Children's Hospital of Philadelphia Clinical & Translational Science Award (CTSA). Jeffrey S. Barrett, Ph.D. of CHOP will direct the core. The core will (a) aid in the development of drug assays; (b) promote and assist in the performance of tracer kinetic studies; (c) develop novel approaches to kinetic data analysis; (d) provide pharmacokinetic (PK), PK– pharmacodynamic (PD), and tracer kinetic modeling; and (e) develop educational modules in pharmacokinetics and tracer kinetics to populate the educational initiatives pursued within the CTSA.”
