Nuclear Receptor Publications

For a complete list of publications please visit  

Yin L , Wang J, Klien PS, Lazar MA.
Nuclear Receptor Rev-erb Is a Critical Lithium-Sensitive Component of the Circadian Clock.
Science. 2006 Feb 17;311(5763):1002-5.
PMID: 16484495

Lehrke M, Lebherz C, Millington SC, Guan HP, Millar J, Rader DJ, Wilson JM, Lazar MA.
Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRalpha.
Cell Metab. 2005 May;1(5):297-308.
PMID: 16054077

Chui PC, Guan HP, Lehrke M, Lazar MA.
PPARgamma regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1.
J Clin Invest. 2005 Aug;115(8):2244-56. Epub 2005 Jul 7.
PMID: 16007265

Yin L, Lazar MA.
The orphan nuclear receptor Rev-erbalpha recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene.
Mol Endocrinol. 2005 Jun;19(6):1452-9. Epub 2005 Mar 10.
PMID: 15761026

Ishizuka T, Lazar MA.
The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor.
Mol Endocrinol. 2005 Jun;19(6):1443-51. Epub 2005 Feb 3.
PMID: 15695367

Guan HP, Ishizuka T, Chui PC, Lehrke M, Lazar MA.
Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes.
Genes Dev. 2005 Feb 15;19(4):453-61. Epub 2005 Jan 28.
PMID: 15681609

Rangwala SM, Rhoades B, Shapiro JS, Rich AS, Kim JK, Shulman GI, Kaestner KH, Lazar MA.
Genetic modulation of PPARgamma phosphorylation regulates insulin sensitivity.
Dev Cell. 2003 Oct;5(4):657-63.
PMID: 14536066

Ishizuka T, Lazar MA.
The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor.
Mol Cell Biol. 2003 Aug;23(15):5122-31.
PMID: 12861000

Yu J, Li Y, Ishizuka T, Guenther MG, Lazar MA.
A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation.
EMBO J. 2003 Jul 1;22(13):3403-10.
PMID: 12840002

Li Y, Lazar MA.
Differential gene regulation by PPARgamma agonist and constitutively active PPARgamma2.
Mol Endocrinol. 2002 May;16(5):1040-8.
PMID: 11981038

Hu X, Li Y, Lazar MA.
Determinants of CoRNR-dependent repression complex assembly on nuclear hormone receptors.
Mol Cell Biol. 2001 Mar;21(5):1747-58.
PMID: 11238912









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