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Pruning of the Adipocyte PPAR{gamma} Cistrome by Hematopoietic Master Regulator PU.1.
Dispirito JR, Fang B, Wang F, Lazar MA.
Mol Cell Biol. 2013 Jun 17. [Epub ahead of print] PMID: 23775123 [PubMed - as supplied by publisher]

Cell-specific integration of nuclear receptor function at the genome.
Everett LJ, Lazar MA.
Wiley Interdiscip Rev Syst Biol Med. 2013 Jun 11. doi: 10.1002/wsbm.1231. [Epub ahead of print] PMID: 23757177 [PubMed - as supplied by publisher]

Integrative genomic analysis of CREB defines a critical role for transcription factor networks in mediating the fed/fasted switch in liver.
Everett LJ, Lay JL, Lukovac S, Bernstein D, Steger DJ, Lazar MA, Kaestner KH.
BMC Genomics. 2013 May 17;14:337. doi: 10.1186/1471-2164-14-337.PMID: 23682854 [PubMed - in process]

Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo.
You SH, Lim HW, Sun Z, Broache M, Won KJ, Lazar MA.
Nat Struct Mol Biol. 2013 Jan 6. doi: 10.1038/nsmb.2476. [Epub ahead of print] PMID:23292142 [PubMed - as supplied by publisher]

A novel adipose-specific gene deletion model demonstrates potential pitfalls of existing methods.
Mullican SE, Tomaru T, Gaddis CA, Peed LC, Sundaram A, Lazar MA.
Mol Endocrinol. 2013 Jan;27(1):127-34. doi: 10.1210/me.2012-1267. Epub 2012 Nov 28. PMID: 23192980 [PubMed - in process]

Double SET point: G9a makes its mark in adipogenesis.
Cristancho AG, Lazar MA.
EMBO J. 2013 Jan 9;32(1):4-6. doi: 10.1038/emboj.2012.320. Epub 2012 Nov 27. No abstract available. PMID: 23188078 [PubMed - in process]

Dissociating fatty liver and diabetes.
Sun Z, Lazar MA.
Trends Endocrinol Metab. 2013 Jan;24(1):4-12. doi: 10.1016/j.tem.2012.09.005. Epub 2012 Oct 5. PMID: 23043895 [PubMed - in process]

Nuclear factor-kB binding motifs specify Toll-like receptor-induced gene repression through an inducible repressosome.
Yan Q, Carmody RJ, Qu Z, Ruan Q, Jager J, Mullican SE, Lazar MA, Chen YH.
Proc Natl Acad Sci U S A. 2012 Aug 13. [Epub ahead of print] PMID: 22891325 [PubMed - as supplied by publisher]

Clocks, metabolism, and the epigenome.
Feng D, Lazar MA.
Mol Cell. 2012 Jul 27;47(2):158-67. PMID: 22841001 [PubMed - in process]

Physiology. De-meaning of metabolism.
Lazar MA, Birnbaum MJ.
Science. 2012 Jun 29;336(6089):1651-2. PMID: 22745413 [PubMed - in process]

Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.
Sinha RA, You SH, Zhou J, Siddique MM, Bay BH, Zhu X, Privalsky ML, Cheng SY, Stevens RD, Summers SA, Newgard CB, Lazar MA, Yen PM.
J Clin Invest. 2012 Jul 2;122(7):2428-38. doi: 10.1172/JCI60580. Epub 2012 Jun 11. PMID: 22684107 [PubMed - in process]

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration.
Sun Z, Miller RA, Patel RT, Chen J, Dhir R, Wang H, Zhang D, Graham MJ, Unterman TG, Shulman GI, Sztalryd C, Bennett MJ, Ahima RS, Birnbaum MJ, Lazar MA.
Nat Med. 2012 May 6. doi: 10.1038/nm.2744. [Epub ahead of print] PMID: 22561686

Rev-erbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function.
Bugge A, Feng D, Everett LJ, Briggs ER, Mullican SE, Wang F, Jager J, Lazar MA
Genes Dev. 2012 Apr 1;26(7):657-67. PMID:22474260 [PubMed - in process]

Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation.
Mullican SE, Gaddis CA, Alenghat T, Nair MG, Giacomin PR, Everett LJ, Feng D, Steger DJ, Schug J, Artis D, Lazar MA.
Genes Dev. 2011 Dec 1;25(23):2480-8. PMID: 22156208 [PubMed - in process]

Histone deacetylase 3 regulates smooth muscle differentiation in neural crest cells and development of the cardiac outflow tract.
Singh N, Trivedi CM, Lu M, Mullican SE, Lazar MA, Epstein JA.
Circ Res. 2011 Nov 11;109(11):1240-9. Epub 2011 Sep 29. PMID: 21959220 [PubMed - in process]

Forming functional fat: a growing understanding of adipocyte differentiation.
Cristancho AG, Lazar MA.
Nat Rev Mol Cell Biol. 2011 Sep 28;12(11):722-34. doi: 10.1038/nrm3198. PMID: 21952300 [PubMed - in process]

Repressor transcription factor 7-like 1 promotes adipogenic competency in precursor cells.
Cristancho AG, Schupp M, Lefterova MI, Cao S, Cohen DM, Chen CS, Steger DJ, Lazar MA.
Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16271-6. Epub 2011 Sep 13. PMID: 21914845 [PubMed - in process]

Circadian Epigenomic Remodeling and Hepatic Lipogenesis: Lessons from HDAC3.
Sun Z, Feng D, Everett LJ, Bugge A, Lazar MA.
Cold Spring Harb Symp Quant Biol. 2011 Sep 6. [Epub ahead of print] PMID: 21900149 [PubMed - as supplied by publisher]

Resistin Levels in Lupus and Associations with Disease-specific Measures, Insulin Resistance, and Coronary Calcification.
Baker JF, Morales M, Qatanani M, Cucchiara A, Nackos E, Lazar MA, Teff K, VON Feldt JM.
J Rheumatol. 2011 Nov;38(11):2369-75. Epub 2011 Sep 1. PMID: 21885493 [PubMed - in process]

Diet-induced lethality due to loss of HDAC3 in heart and skeletal muscle.
Sun Z, Singh N, Mullican SE, Everett LJ, Li L, Yuan L, Liu X, Epstein JA, Lazar MA.
J Biol Chem. 2011 Aug 1. [Epub ahead of print]. PMID: 21808063 [PubMed - as supplied by publisher]

A hormone sends instant messages to the genome.
Prokesch A, Lazar MA.
Cell. 2011 May 13;145(4):499-501. PMID: 21565609 [PubMed]

Adipogenic hotspots: where the action is.
Steger DJ, Lazar MA.
EMBO J. 2011 Apr 20;30(8):1418-9. No abstract available. PMID: 21505519 [PubMed - in process]

Human resistin: found in translation from mouse to man.
Schwartz DR, Lazar MA.
Trends Endocrinol Metab. 2011 Apr 14. [Epub ahead of print] PMID: 21497511

A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism.
Feng D, Liu T, Sun Z, Bugge A, Mullican SE, Alenghat T, Liu XS, Lazar MA.
Science. 2011 Mar 11;331(6022):1315-9. PMID: 21393543[PubMed - in process]

Species-Specific Strategies Underlying Conserved Functions of Metabolic Transcription Factors.
Soccio RE, Tuteja G, Everett LJ, Li Z, Lazar MA, Kaestner KH.
Mol Endocrinol. 2011 Feb 3. [Epub ahead of print] PMID: 21292830

Inflammatory Induction of Human Resistin Causes Insulin Resistance in Endotoxemic Mice.
Park HK, Qatanani M, Briggs ER, Ahima RS, Lazar MA.
Diabetes. 2011 Jan 31. [Epub ahead of print] PMID: 21282361

HDAC3 is a critical negative regulator of long-term memory formation.
McQuown SC, Barrett RM, Matheos DP, Post RJ, Rogge GA, Alenghat T, Mullican SE, Jones S, Rusche JR, Lazar MA, Wood MA.
J Neurosci. 2011 Jan 12;31(2):764-74. PMID: 21228185

Autoimmune Kidney Disease and Impaired Engulfment of Apoptotic Cells in Mice with Macrophage Peroxisome Proliferator-Activated Receptor {gamma} or Retinoid X Receptor {alpha} Deficiency.
Roszer T, Menéndez-Gutiérrez MP, Lefterova MI, Alameda D, Núñez V, Lazar MA, Fischer T, Ricote M.
J Immunol. 2011 Jan 1;186(1):621-31. Epub 2010 Dec 6. PMID: 21135166

Endogenous Ligands for Nuclear Receptors: Digging Deeper.
Schupp M, Lazar MA.
J Biol Chem. 2010 Dec 24;285(52):40409-15. Epub 2010 Oct 18. PMID: 20956526

Transcriptional repressor E4 binding protein 4 (E4BP4) regulates metabolic hormone fibroblast growth factor 21 (FGF21) during circadian cycles and feeding.
Tong X, Muchnik M, Chen Z, Patel M, Wu N, Joshi S, Rui L, Lazar MA, Yin L.
J Biol Chem. 2010 Nov 19;285(47):36401-9. Epub 2010 Sep 17.PMID: 20851878

GSK4112, a Small Molecule Chemical Probe for the Cell Biology of the Nuclear Heme Receptor Rev-erbalpha.
Grant D, Yin L, Collins JL, Parks DJ, Orband-Miller LA, Wisely GB, Joshi S, Lazar MA, Willson TM, Zuercher WJ.
ACS Chem Biol. 2010 Oct 15;5(10):925-32.

Structure of Rev-erbalpha bound to N-CoR reveals a unique mechanism of nuclear receptor-co-repressor interaction.
Phelan CA, Gampe RT Jr, Lambert MH, Parks DJ, Montana V, Bynum J, Broderick TM, Hu X, Williams SP, Nolte RT, Lazar MA.
Nat Struct Mol Biol. 2010 Jul;17(7):808-14. Epub 2010 Jun 27. PMID: 20581824 [PubMed - indexed for MEDLINE]

E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha.
Yin L, Joshi S, Wu N, Tong X, Lazar MA.
Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11614-9. Epub 2010 Jun 7.PMID: 20534529

Propagation of adipogenic signals through an epigenomic transition state.
Steger DJ, Grant GR, Schupp M, Tomaru T, Lefterova MI, Schug J, Manduchi E, Stoeckert CJ Jr, Lazar MA.
Genes Dev. 2010 May 15;24(10):1035-44.PMID: 20478996

The Interaction between Nuclear Receptor Corepressor and Histone Deacetylase 3 Regulates Both Positive and Negative Thyroid Hormone Action in Vivo.
You SH, Liao X, Weiss RE, Lazar MA.
Mol Endocrinol. 2010 Jul;24(7):1359-67. Epub 2010 Apr 28. PMID: 20427468

Nuclear receptor Rev-erbalpha: a heme receptor that coordinates circadian rhythm and metabolism.
Yin L, Wu N, Lazar MA.
Nucl Recept Signal. 2010 Apr 16;8:e001.

Fingered for a fat fate.
Schupp M, Lazar MA.
Cell Metab. 2010 Apr 7;11(4):244-5.

Cell-Specific Determinants of PPAR{gamma} Function in Adipocytes and Macrophages.
Lefterova MI, Steger DJ, Zhuo D, Qatanani M, Mullican SE, Tuteja G, Manduchi E, Grant GR, Lazar MA.
Mol Cell Biol. 2010 Feb 22. [Epub ahead of print]

Negative feedback maintenance of heme homeostasis by its receptor, Rev-erb{alpha}
Wu N, Yin L, Hanniman EA, Joshi S, Lazar MA.
Genes Dev. 2009 Sep 15;23(18):2201-9. Epub 2009 Aug 26.

Brown Fat in Humans: Turning up the Heat on Obesity.
Seale P, Lazar MA.
Diabetes. 2009 Jul;58(7):1482-4.

Endoplasmic Reticulum Stress Regulates Adipocyte Resistin Expression.
Lefterova MI, Mullican SE, Tomaru T, Qatanani M, Schupp M, Lazar MA.
Diabetes. 2009 Jun 2. [Epub ahead of print]

Differential action on coregulator interaction defines inverse retinoid agonists and neutral antagonists.
Germain P, Gaudon C, Pogenberg V, Sanglier S, Van Dorsselaer A, Royer CA, Lazar MA, Bourguet W, Gronemeyer H.
Chem Biol. 2009 May 29;16(5):479-89.

New developments in adipogenesis.
Lefterova MI, Lazar MA.
Trends Endocrinol Metab. 2009 Apr;20(3):107-14. Epub 2009 Mar 9.

Macrophage-derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice.
Qatanani M, Szwergold NR, Greaves DR, Ahima RS, Lazar MA.
J Clin Invest. 2009 Feb 2. pii: 37273. doi: 10.1172/JCI37273. [Epub ahead of print]

Retinol saturase promotes adipogenesis and is downregulated in obesity.
Schupp M, Lefterova MI, Janke J, Leitner K, Cristancho AG, Mullican SE, Qatanani M, Szwergold N, Steger DJ, Curtin JC, Kim RJ, Suh M, Albert MR, Engeli S, Gudas LJ, Lazar MA.
Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1105-10.

Re-expression of GATA2 cooperates With PPARgamma depletion to revert the adipocyte phenotype.
Schupp M, Cristancho AG, Lefterova MI, Hanniman EA, Briggs ER, Steger DJ, Qatanani M, Curtin JC, Schug J, Ochsner SA, McKenna NJ, Lazar MA.
J Biol Chem. 2009 Apr 3;284(14):9458-64.

Adipocyte-specific expression of murine resistin is mediated by synergism between peroxisome proliferator-activated receptor gamma and CCAAT/enhancer binding proteins.
Tomaru T, Steger DJ, Lefterova MI, Schupp M, Lazar MA.
J Biol Chem. 2009 Mar 6;284(10):6116-25.

Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology.
Alenghat T, Meyers K, Mullican SE, Leitner K, Adeniji-Adele A, Avila J, Bucan M, Ahima RS, Kaestner KH, Lazar MA.
Nature. 2008 Dec 18;456(7224):997-1000. Epub 2008 Nov 26.

PPARgamma and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale.
Lefterova MI, Zhang Y, Steger DJ, Schupp M, Schug J, Cristancho A, Feng D, Zhuo D, Stoeckert CJ Jr, Liu XS, Lazar MA.
Genes Dev. 2008 Nov 1;22(21):2941-52.

Selective Partial Agonism of Liver X Receptor {alpha} Is Related to Differential Corepressor Recruitment.
Phelan CA, Weaver JM, Steger DJ, Joshi S, Maslany JT, Collins JL, Zuercher WJ, Willson TM, Walker M, Jaye M, Lazar MA.
Mol Endocrinol. 2008 Oct;22(10):2241-9.

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.
Kajimura S, Seale P, Tomaru T, Erdjument-Bromage H, Cooper MP, Ruas JL, Chin S, Tempst P, Lazar MA, Spiegelman BM.
Genes Dev. 2008 May 15;22(10):1397-409.

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.
Steger DJ, Lefterova MI, Ying L, Stonestrom AJ, Schupp M, Zhuo D, Vakoc AL, Kim JE, Chen J, Lazar MA, Blobel GA, Vakoc CR.
Mol Cell Biol. 2008 Apr;28(8):2825-39.

Bifunctional Role of Rev-erba in Adipocyte Differentiation.
Wang J, Lazar MA.
Mol Cell Biol. 2008 Apr;28(7):2213-20.

Rev-erba, a heme sensor that coordinates metabolic and circadian pathways.
Yin L, Wu N, Curtin JC, Qatanani M, Szwergold NR, Reid RA, Waitt GM, Parks DJ, Pearce KH, Wisely GB, Lazar MA
Science. 2007 Dec 14;318(5857):1786-9.

A widely used retinoic acid receptor antagonist induces peroxisome proliferator-activated receptor-gamma activity.
Schupp M, Curtin JC, Kim RJ, Billin AN, Lazar MA.
Mol Pharmacol. 2007 May;71(5):1251-7.

CXCL16 is a marker of inflammation, atherosclerosis, and acute coronary syndromes in humans.
Lehrke M, Millington SC, Lefterova M, Cumaranatunge RG, Szapary P, Wilensky R, Rader DJ, Lazar MA, Reilly MP
J Am Coll Cardiol. 2007 Jan 30;49(4):442-9.

The orphan nuclear receptor Rev-erb alpha regulates circadian expression of plasminogen activator inhibitor type 1.
Wang J, Yin L, Lazar MA.
J Biol Chem. 2006 Nov 10;281(45):33842-8.

The corepressor silencing mediator for retinoid and thyroid hormone receptor facilitates cellular recovery from DNA double-strand breaks.
Yu J, Palmer C, Alenghat T, Li Y, Kao G, Lazar MA
Cancer Res. 2006 Sep 15;66(18):9316-22.

A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity.
Li Y, Kao GD, Garcia BA, Shabanowitz J, Hunt DF, Qin J, Phelan C, Lazar MA.
Genes Dev. 2006 Sep 15;20(18):2566-79.

The N-CoR complex enables chromatin remodeler SNF2H to enhance repression by thyroid hormone receptor.
Alenghat T, Yu J, Lazar MA.
EMBO J. 2006 Sep 6;25(17):3966-74.

HIV protease inhibitor-specific alterations in human adipocyte differentiation and metabolism.
Kim RJ, Wilson CG, Wabitsch M, Lazar MA, Steppan CM.
Obesity (Silver Spring). 2006 Jun;14(6):994-1002.

Nutritional supplementation with trans-10, cis-12-conjugated linoleic acid induces inflammation of white adipose tissue.
Poirier H, Shapiro JS, Kim RJ, Lazar MA.
Diabetes. 2006 Jun;55(6):1634-41.

Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock.
Yin L, Wang J, Klein PS, Lazar MA.
Science. 2006 Feb 17;311(5763):1002-5.

PPARgamma regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1.
Chui PC, Guan HP, Lehrke M, Lazar MA.
J Clin Invest. 2005 Aug;115(8):2244-56.

The orphan nuclear receptor Rev-erba recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene.
Yin L, Lazar MA.
Mol Endocrinol. 2005 Jun;19(6):1452-9.

The histone-binding code of nuclear receptor co-repressors matches the substrate specificity of histone deacetylase 3.
Hartman HB, Yu J, Alenghat T, Ishizuka T, Lazar MA.
EMBO Rep. 2005 May;6(5):445-51.

Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRalpha.
Lehrke M, Lebherz C, Millington SC, Guan HP, Millar J, Rader DJ, Wilson JM, Lazar MA.
Cell Metab. 2005 May;1(5):297-308.

The Nuclear Receptor Corepressor Deacetylase Activating Domain is Essential for Repression by Thyroid Hormone Receptor.
Ishizuka T, Lazar MA.
Mol Endocrinol. 2005 Feb 3.

Activation of SOCS-3 by resistin.
Steppan CM, Wang J, Whiteman EL, Birnbaum MJ, Lazar MA.
Mol Cell Biol. 2005 Feb;25(4):1569-75.

Corepressors selectively control the transcriptional activity of PPAR{gamma} in adipocytes.
Guan HP, Ishizuka T, Chui PC, Lehrke M, Lazar MA.
Genes Dev. 2005 Feb 15;19(4):453-61.

An Inflammatory Cascade Leading to Hyperresistinemia in Humans.
Lehrke M, Reilly MP, Millington SC, Iqbal N, Rader DJ, Lazar MA.
PLoS Med. 2004 Nov;1(2):e45.

Abnormal glucose homeostasis due to chronic hyperresistinemia.
Rangwala SM, Rich AS, Rhoades B, Shapiro JS, Obici S, Rossetti L, Lazar MA.
Diabetes 2004 Aug;53(8):1937-41..

A chromatin immunoprecipitation screen reveals protein kinase Cbeta as a direct RUNX1 target gene.
Hug BA, Ahmed N, Robbins JA, Lazar MA.
J Biol Chem. 2004 Jan 9;279(2):825-30.

Genetic modulation of PPARgamma phosphorylation regulates insulin sensitivity.
Rangwala SM, Rhoades B, Shapiro JS, Rich AS, Kim JK, Shulman GI, Kaestner KH, Lazar MA.
Dev Cell. 2003 Oct;5(4):657-63.

The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor.
Ishizuka T, Lazar MA.
Mol Cell Biol. 2003 Aug;23(15):5122-31.

A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation.
Yu J, Li Y, Ishizuka T, Guenther MG, Lazar MA.
EMBO J. 2003 Jul 1;22(13):3403-10.

Assembly of the SMRT-histone deacetylase 3 repression complex requires the TCP-1 ring complex.
Guenther MG, Yu J, Kao GD, Yen TJ, Lazar MA.
Genes Dev. 2002 Dec 15;16(24):3130-5.

A futile metabolic cycle activated in adipocytes by antidiabetic agents.
Guan HP, Li Y, Jensen MV, Newgard CB, Steppan CM, Lazar MA.
Nat Med. 2002 Oct;8(10):1122-8.

Mechanisms regulating adipocyte expression of resistin.
Hartman HB, Hu X, Tyler KX, Dalal CK, Lazar MA.
J Biol Chem. 2002 May 31;277(22):19754-61.

Differential gene regulation by PPARgamma agonist and constitutively active PPARgamma2.
Li Y, Lazar MA.
Mol Endocrinol. 2002 May;16(5):1040-8.

The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3.
Guenther MG, Barak O, Lazar MA.
Mol Cell Biol. 2001 Sep;21(18):6091-101.

Dimerization of resistin and resistin-like molecules is determined by a single cysteine.
Banerjee RR, Lazar MA.
J Biol Chem. 2001 Jul 13;276(28):25970-3.


Determinants of CoRNR-dependent repression complex assembly on nuclear hormone receptors.
Hu X, Li Y, Lazar MA.
Mol Cell Biol. 2001 Mar;21(5):1747-58.

The hormone resistin links obesity to diabetes.
Steppan CM, Bailey ST, Bhat S, Brown EJ, Banerjee RR, Wright CM, Patel HR, Ahima RS, Lazar MA.
Nature. 2001 Jan 18;409(6818):307-12.

A family of tissue-specific resistin-like molecules.
Steppan CM, Brown EJ, Wright CM, Bhat S, Banerjee RR, Dai CY, Enders GH, Silberg DG, Wen X, Wu GD, Lazar MA.
Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):502-6.

Oligomerization of ETO is obligatory for corepressor interaction.
Zhang J, Hug BA, Huang EY, Chen CW, Gelmetti V, Maccarana M, Minucci S, Pelicci PG, Lazar MA.
Mol Cell Biol. 2001 Jan;21(1):156-63.

 

Review Articles:

Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas.
McKenna NJ, Cooney AJ, Demayo FJ, Downes M, Glass CK, Lanz RB, Lazar MA, Mangelsdorf DJ, Moore DD, Qin J, Steffen DL, Tsai MJ, Tsai SY, Yu R, Margolis RN, Evans RM, O'Malley BW.
Mol Endocrinol. 2009 Jun;23(6):740-6. Epub 2009 May 7.

Developmental biology. How now, brown fat?
Lazar MA.
Science. 2008 Aug 22;321(5892):1048-9.

Adipokines and the Peripheral and Neural Control of Energy Balance.
Ahima RS, Lazar MA.
Mol Endocrinol. 2008 May;22(5):1023-31.

Resistin- and Obesity-associated metabolic diseases.
Lazar MA.
Horm Metab Res. 2007 Oct;39(10):710-6.

Mechanisms of obesity-associated insulin resistance: many choices on the menu.
Qatanani M, Lazar MA.
Genes Dev. 2007 Jun 15;21(12):1443-55.

The humoral side of insulin resistance.
Lazar MA.
Nat Med. 2006 Jan;12(1):43-4.

The many faces of PPARgamma.
Lehrke M, Lazar MA.
Cell. 2005 Dec 16;123(6):993-9.

How obesity causes diabetes: not a tall tale.
Lazar MA.
Science. 2005 Jan 21;307(5708):373-5.

Peroxisome proliferator-activated receptor gamma in diabetes and metabolism.
Rangwala SM, Lazar MA.
Trends Pharmacol Sci. 2004 Jun;25(6):331-6.

Inflamed about obesity.
Lehrke M, Lazar MA.
Nat Med. 2004 Feb;10(2):126-127.

East meets West: an herbal tea finds a receptor.
Lazar MA.
J Clin Invest. 2004 Jan;113(1):23-5.

Thyroid hormone action: a binding contract.
Lazar MA
J Clin Invest. 2003 Aug;112(4):497-9. .

Resistin: molecular history and prognosis.
Banerjee RR, Lazar MA.
J Mol Med. 2003 Apr;81(4):218-26.

Becoming fat.
Lazar MA.
Genes Dev. 2002 Jan 1;16(1):1-5.

Progress in cardiovascular biology: PPAR for the course.
Lazar MA.
Nat Med. 2001 Jan;7(1):23-4.

 

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