Josh Lipschutz, MD (Pricipal Investigator)
|Assistant Professor of Medicine||2001-present||University of Pennsylvania, Philadelphia, PA|
|Cell and Molecular Biology Graduate Group||2001-present||University of Pennsylvania, Philadelphia, PA|
|Chief, Nephrology Section, Philadelphia VAMC||2008-present||Philadelphia, PA|
|Lieutenant Colonel Pennsylvania Army National Guard, Medical Detachment||2008-present|
|Major, Pennsylvania Army National Guard, Medical Detachment||2003-2008|
|Active Duty Deployment, Community-Based Wounded Warrior Transition Unit||2010||Redstone Arsenal, Huntsville, A.|
|Active Duty Deployment to Battalion Aid Station||2007-2008||Mehtar Lam, Afghanistan|
|Active Duty Deployment to Forward Support Hospital||2005||Baghdad, Iraq|
|Assistant Clinical Professor of Medicine, Assistan Research Anatomist||1997-2001||University of California, San Francisco|
|Visiting Postdoctoral Fellow||1996-1997||Weizmann Institute of Science, Rehovot, Israel|
|Clinical Instructor||1995-1997||University of California, San Francisco|
|Nephrology Fellowship||1992-1995||University of California, San Francisco|
|National Emergency Services, Medical Director||1991-1992||Putnam County Hospital Emergency Room, Greencastle, IN|
|Internal Medicine Residency||1989-1991||Indiana University, Indianapolis, IN|
|Internal Medicine Internship||1988-1989||Michael Reese Hospital, Chicago, IL|
|MD - Indiana University, Indianapolis, IN||1988|
|BA - Chemistry, Indiana University, Indianapolis, IN||1984|
Dr. Lipschutz's research involves kidney development, how this process goes awry in polycystic kidney disease and how it contributes to the recovery that follows acute kidney injury. In his basic science lab, these questions are examined at a cellular and molecular as well as a translational level.
Dr. Lipschutz has a military background as a physician in the Pennsylvania Army National Guard with active duty deployments to both Iraq and Afghanistan. He treats men and women who seek medical care at the Philadelphia VAMC where he is also the Chief of Nephrology.
Xiaofeng Zuo, PhD (Research Specialist)
|Research Specialist||2007-present||University of Pennsylvania, Department of Medicine|
|Research Associate||2006-2007||University of Pennsylvania, Department of Medicine|
|Postdoctoral Fellow||2001-2006||University of Pennsylvania, Department of Biology|
|PhD - Biochemistry and Molecular Biology||2001||Peking University, Department of Biochemistry and Molecular Biology|
Liwei Huang, MD, PhD (Research Specialist)
Soo Young Choi, PhD
|Postdoctoral Fellow||2011-present||University of Pennsylvania, Department of Medicine, Philadelphia, PA|
|PhD - Biology, Human Genetics||2011||Kyungpook National University, South Korea
Advisor: Dr. Un-Kyung Kim, PhD
|MS - Biology||2008||Kyungpook National University, South Korea|
|BS - Biology||2006||Kyungpook National University, South Korea|
- PKD and mechanisms of ciliopathy
My goal is to better understand the pathogenesis of human PKD, and lay the groundwork for the discovery of novel therapies. I'm currently studying the roles of the small GTPase Cdc42 in Renal ciliogenesis and cystogenesis using zebrafish and mouse models.
Maria F. Chacon-Heszele, PhD
|Postdoctoral Fellow||August 201 - present||University of Pennsylvania, Philadelphia PA|
|Postdoctoral Fellow||May 2011 - July 2012||Emory University, Atlanta, GA|
|PhD - Biochemistry, Cell and Developmental Biology||May 2011||Emory University, Atlanta, GA
Dissertation Advisor: Ping Chen
|BS - Biochemistry, BA - Chemistry||2004||Advisor: Phil Pekala|
- Role of ciliary signaling during organogenesis.
During my graduate studies, I focused on the role of Planar Cell Polarity (PCP)/ciliary signaling during the morphogenesis of the mouse inner ear.
Now I focus on the role of the exocyst complex in the regulation of the novel urocrine signaling pathway. Additionally, I am testing the use of adeno-associated viruses (AAV) as therapeutic agents for autosomal dominant polycystic kidney disease (ADPKD) and acute kidney injury.
Sarah McKenna (Undergraduate)
|BA - Biology||Spring 2013||University of Pennsylvania, College of Arts and Sciences|