Methods and Applications in the Next Generation Sequencing Age
The Center for Genetics and Complex Traits (CGACT) of the University of Pennsylvania hosted a one-day conference on Genetic Epidemiology and Statistics: Methods and Applications in the NGS Age, on May 17, 2013 at the Sheraton Philadelphia University City Hotel near the campus of the University of Pennsylvania in Philadelphia, PA.
The conference intended to bring together an interdisciplinary group of scientists working in the fields of statistical genetics and genetic epidemiology. The forum provided an opportunity for faculty, postdoctoral fellows, and graduate students working in these fields to convene and review new developments in these areas of research. The program featured three sessions with three invited speakers each and allowed for formal as well as informal discussion. The conference aimed to facilitate exchange of ideas and promote interactions and collaborations among participants.
The 2013 MAGES Conference was sponsored by the Center for Clinical Epidemiology and Biostatistics (CCEB) of the University of Pennsylvania.
10:15-10:30 Timothy Rebbeck & Harold Feldman (Penn): Welcome and opening remarks
Session 1: GWAS developments and applications (Moderator: Danish Saleheen, Penn)
10:30-11:00 Tara Matise (Rutgers): The Next PAGE: Examples from the Population Architecture using Genomics and Epidemiology Study
11:00-11:30 Hongyu Zhao (Yale): Incorporating prior information in GWAS: how far can we go?
11:30-12:00 Nilanjan Chatterjee (NCI): Risk prediction based on hidden heritability in genome-wide association studies
Session 2: New methods in statistical genetics (Moderator: Jinbo Chen, Penn)
1:30-2:00 Ingo Ruczinski (Johns Hopkins): Methods for genetic studies with case-parent trios
2:00-2:30 Jaya Satagopan (MSKCC): Evaluation of statistical interactions for binary traits
2:30-3:00 Kathryn Roeder (Carnegie Mellon): Estimating genetically inferred relationships using Treelets
3:00-3:30 Coffee break
Session 3: Analysis of NGS data (Moderator: Mingyao Li, Penn)
3:30-4:00 Iuliana Ionita-Laza (Columbia): Sequence-based association tests and applications
4:00-4:30 Joan Bailey-Wilson (NHGRI): Family-based strategies for analyses of next generation sequence data
4:30-5:00 Adam Naj (Penn): Filter Feeding: Principled exploratory filtering approaches for sequence data to identify variants, genes, and regions for genetic follow-up studies
5:00-5:30 Hongzhe Li (Penn): Conclusions