Kazanietz Lab > Movies
Video 1: Translocation of beta-2-chimaerin by PMA
Translocation of GFP-beta-2-chimaerin to the perinuclear region by PMA in COS-1 cells. The video was recorded during 20 minutes since the of addition of PMA.
Video 2: A C1 domain mutated form of beta-2-chimaerin is unresponsive to PMA
Lack of translocation of a GFP-beta-2-chimaerin mutant in which essential Cys246 in the C1 domain has been mutated to Ala (C246A mutant). This mutant is phorbol ester/DAG unresponsive. The video was recorded during 20 minutes since the of addition of PMA.