The Kazanietz Laboratory
Department of Pharmacology and Institute for Translational Medicine and Therapeutics (ITMAT)

Kazanietz Lab > Movies

Movies

All movies are in AVI format and playable in Apple's Quicktime Player or Microsoft Window's Media Player. Videos are not in streaming format.

Video 1: Translocation of beta-2-chimaerin by PMA

2.5 MB

Translocation of GFP-beta-2-chimaerin to the perinuclear region by PMA in COS-1 cells. The video was recorded during 20 minutes since the of addition of PMA.

Video 2: A C1 domain mutated form of beta-2-chimaerin is unresponsive to PMA

3.7 MB

Lack of translocation of a GFP-beta-2-chimaerin mutant in which essential Cys246 in the C1 domain has been mutated to Ala (C246A mutant). This mutant is phorbol ester/DAG unresponsive. The video was recorded during 20 minutes since the of addition of PMA.