Frederic D. Bushman, Ph.D.

Professor, Department of Microbiology

Office Address:
University of Pennsylvania School of Medicine
402C Johnson Pavilion
3610 Hamilton Walk
Philadelphia, PA 19104

TEL 215-573-8732
LAB 215-573-8733
FAX 215-573-4856
bushman@mail.med.upenn.edu

Go to the Bushman Lab Site

RESEARCH SUMMARY

Research in my laboratory focuses on understanding host-virus interactions, with the dual goal of understanding mechanisms and developing inhibitors. We use a combination of methods in our work--where possible, we try to combine high throughput methods such as deep sequencing, high throughput screening, and RNAi, with more traditional methods such as biochemistry and structural biology. Several of our projects focus on the function of viral DNA modifying enzymes, such as the integrase of HIV and the resolvase and topoisomerase of variola (smallpox) virus.

For full description, illustrations and references, see the Bushman Lab Site.