The bacteriology program at Penn is growing, with 4 new faculty having been
hired over the past 5 years. Particular areas of interest include type III
secretion
systems, interactions between the pathogen and the host cell, and small animal
models. Listeria monocytogenes is studied by a large number of investigators,
including those who use recombinant listeria vectors for studies on mucosal immunity
and vaccine development. Studies on translation, DNA methylation, and other
basic
processes are also the focus of research programs.
| Andrew
Binns |
Agrobacterum tumefaciens; host-pathogen interaction; type IV secretion |
| Dustin Brisson |
Disease ecology; molecular evolution; microbial ecology/ evolution; host-pathogen interaction |
| Igor Brodsky |
Host-pathogen interactions; bacterial pathogenesis; Yersinia; innate immunity |
| Frederic Bushman |
Metagenomic analysis of bacterial communities |
| Fevzi Daldal |
Photosynthetic and respiratory electron transfer pathways and structure; function and biogenesis of cytochrome complexes |
| Howard Goldfine |
Identification of novel bacterial membrane lipids; response of membrane lipids to solvent stress |
| Mark
Goulian |
Bacterial regulatory networks; two-component signaling; genetic diversity among E. coli |
| Akira Kaji |
Translation; ribosome recycling in bacteria and yeast;
antibacterial agents; antifungal agents |
| Rahul Kohli |
Antibiotic resistance; SOS response; novel antimicrobial approaches |
| Irving
Nachamkin |
GI infections; Campylobacter; antimicrobial resistance; diagnostic microbiology |
| Yvonne Paterson |
Tumor immunology; Listeria monocytogenes; vaccines against infectious and neoplastic disease |
| Mecky
Pohlschroder |
Protein secretion; membrane protein insertion; archaea |
| Dieter
Schifferli |
Escherichia coli and Salmonella pathogenesis; fimbriae;
vaccines |
| Phil Scott |
T helper cell subsets; IL-12; T cell memory; Leishmania |
| Michael Sebert |
Streptococcus; pneumoniae pathogenesis; quorum sensing; two-component signaling |
| Hao Shen |
Bacterial pathogenesis and mechanisms of immune evasion; L. monocytogenes; Flu/bacterial co-infection; secondary pneumonia by S. pneumoniae & H. influenzae |
| Sunny Shin |
Immunity against bacterial pathogens; bacterial pathogenesis; Legionella pneumophila |
| Jeff Weiser |
S. pneumoniae & H. influenzae pathogenesis; mucosal colonization; co-infection; microbial immunology |
| Jun (Jay) Zhu |
Quorum sensing; bacterial pathogenesis; Vibrio cholerae and virulence gene regulation; biofilms |
