The bacteriology program at Penn is growing, with 4 new faculty having been
hired over the past 5 years. Particular areas of interest include type III
secretion
systems, interactions between the pathogen and the host cell, and small animal
models. Listeria monocytogenes is studied by a large number of investigators,
including those who use recombinant listeria vectors for studies on mucosal immunity
and vaccine development. Studies on translation, DNA methylation, and other
basic
processes are also the focus of research programs.
| Andrew
Binns |
Agrobacterum tumefaciens; host-pathogen
interaction; type IV secretion |
| Dustin Brisson |
Disease ecology, molecular evolution, microbial ecology/
evolution, host-pathogen interaction |
| Igor Brodsky |
Host-pathogen interactions; bacterial pathogenesis;
Yersinia; innate immunity |
| Frederic Bushman |
Metagenomic analysis of bacterial communities |
| Fevzi Daldal |
Photosynthetic and respiratory electron transfer pathways
and structure, function and biogenesis of cytochrome
complexes |
| Howard Goldfine |
Listeria monocytogenes, Phospholipase C, phagocytosis,
intracellular growth of bacteria, phospholipids, plasmalogens |
| Mark
Goulian |
Bacterial regulatory networks; two-component signaling;
antimicrobial peptides |
| Akira Kaji |
Translation; ribosome recycling factor; antibacterial
agents; antifungal agents |
| Rahul Kohli |
Antimicrobial resistance; SOS pathway |
| Irving
Nachamkin |
Campylobacter pathogenesis; molecular mimicry; diagnostic
microbiology |
| Yvonne Paterson |
Tumor immunology; Listeria monocytogenes; vaccines
against infectious and neoplastic disease |
| Mecky
Pohlschroder |
Protein secretion; membrane protein insertion; archaea |
| Dieter
Schifferli |
Escherichia coli and Salmonella pathogenesis; fimbriae;
vaccines |
| Phil Scott |
T helper cell subsets; IL-12; T cell memory; Leishmania |
| Michael Sebert |
Streptococcus, pneumoniae pathogenesis, quorum sensing,
two-component signaling |
| Hao Shen |
Bacterial pathogenesis and mechanisms of immune evasion;
Listeria monocytogenes; Bacillus anthracis |
| Sunny Shin |
Immunnity against bacterial pathogens; bacterial pathogenesis; Legionella
pneumophila |
| Jeff Weiser |
S. pneumoniae & H influenzae pathogenesis; airway
colonization; phase variation |
| Jun (Jay) Zhu |
Quorum sensing; bacterial pathogenesis; Vibrio cholerae
and virulence gene regulation; biofilms |
