Bacteriology Research

The bacteriology program at Penn is growing, with 4 new faculty having been hired over the past 5 years. Particular areas of interest include type III secretion systems, interactions between the pathogen and the host cell, and small animal models. Listeria monocytogenes is studied by a large number of investigators, including those who use recombinant listeria vectors for studies on mucosal immunity and vaccine development. Studies on translation, DNA methylation, and other basic processes are also the focus of research programs.

Bacteriology Researchers at the University of Pennsylvania
Andrew Binns Agrobacterum tumefaciens; host-pathogen interaction; type IV secretion
Dustin Brisson Disease ecology; molecular evolution; microbial ecology/ evolution; host-pathogen interaction
Igor Brodsky Host-pathogen interactions; bacterial pathogenesis; Yersinia; innate immunity
Frederic Bushman Metagenomic analysis of bacterial communities
Fevzi Daldal Photosynthetic and respiratory electron transfer pathways and structure; function and biogenesis of cytochrome complexes
Howard Goldfine Identification of novel bacterial membrane lipids; response of membrane lipids to solvent stress
Mark Goulian Bacterial regulatory networks; two-component signaling; genetic diversity among E. coli
Akira Kaji Translation; ribosome recycling in bacteria and yeast;
antibacterial agents; antifungal agents
Rahul Kohli Antibiotic resistance; SOS response; novel antimicrobial approaches
Irving Nachamkin GI infections; Campylobacter; antimicrobial resistance; diagnostic microbiology
Yvonne Paterson Tumor immunology; Listeria monocytogenes; vaccines against infectious and neoplastic disease
Mecky Pohlschroder Protein secretion; membrane protein insertion; archaea
Dieter Schifferli Escherichia coli and Salmonella pathogenesis; fimbriae; vaccines
Phil Scott T helper cell subsets; IL-12; T cell memory; Leishmania
Michael Sebert Streptococcus; pneumoniae pathogenesis; quorum sensing; two-component signaling
Hao Shen Bacterial pathogenesis and mechanisms of immune evasion; L. monocytogenes; Flu/bacterial co-infection; secondary pneumonia by S. pneumoniae & H. influenzae
Sunny Shin Immunity against bacterial pathogens; bacterial pathogenesis; Legionella pneumophila
Jeff Weiser S. pneumoniae & H. influenzae pathogenesis; mucosal colonization; co-infection; microbial immunology
Jun (Jay) Zhu Quorum sensing; bacterial pathogenesis; Vibrio cholerae and virulence gene regulation; biofilms

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