Emerging Infectious Diseases Research

Emerging Infectious Diseases

Zoonotic transmission of infectious agents is a major cause of human morbidity and mortality. With increased human population, environmental destruction, ease of international travel and commerce, and break downs in the public health system, emerging infectious diseases are becoming increasingly important. Concerns about bioterrorism have also increased. NIH has greatly increased research support for work on bioterrorism and emerging infectious diseases, and a large number of Penn investigators study viral, parasitic, and bacterial pathogens that are classified as emerging infectious diseases or are possible bioterrorism weopons. A number of Penn investigators study smallpox or viruses that cause hemorrhagic fevers such as Ebola and Dengue. Other topics of research include West Nile virus, Yellow fever virus, anthrax, toxoplasma gondii, and schsitosomiasis.

Emerging Infectious Diseases Researchers at the University of Pennsylvania
Paul Bates Ebola virus; hepatitis C; SARS
Dustin Brisson Disease ecology, molecular evolution, microbial ecology/ evolution, host-pathogen interaction
Frederic Bushman Poxvirus topoisomerases
Sara Cherry Host factors involved in flavivirus pathogenesis
Gary Cohen Smallpox glycoproteins; vaccinia virus
Robert Doms West Nile virus; Dengue virus; Yellow fever; Crimean Congo Hemorragic fever virus; Rift Valley fever virus
Roselyn Eisenberg Smallpox glycoproteins; vaccinia virus
Francisco Gonzalez-Scarano Bunyavirus neuropathogenesis
Doron Greenbaum Protease Function, P.falciparum (malaria),
Chemical biology, Proteomics
Ron Harty Ebola virus
Stuart Isaacs Smallpox vaccine development; vaccinia virus
Irving Nachamkin Campylobacter, food-borne diseases, gastrointestinal infections, Guillain-Barre Syndrome
Robert Ricciardi Smallpox and vaccinia processivity factors
Erle Robertson Karposi's Sarcoma Associated Herpes Virus
David Roos Molecular/cellular parasitology; toxoplasma; plasmodium (malaria); genomics
Dieter Schifferli Yersinia pestis (the plague)
Hao Shen Immune responses and memory; vaccines; Ebola virus; SARS virus; Bacillus anthracis
David Weiner West Nile virus; DNA vaccines; cellular immune responses
Susan Weiss SARS replication, tropism and pathogenesis
James Wilson SARS vaccine development and immune response
Yan Yuan Kaposi's sarcoma-associated herpesvirus
Jun (Jay) Zhu Quorum sensing; bacterial pathogenesis; Vibrio cholerae and virulence gene regulation; biofilms