Parasitology Research

Parasitology

The Parasitology program involves faculty members from different departments within the Schools of Medicine, Veterinary Medicine, and Arts and Sciences whose research interests range from the genetic basis of drug resistance in protozoan parasites to the mathematical modeling of helminth transmission within host populations. Particular areas of emphasis include immunoparasitology in which a large group of faculty focus on understanding immune regulation in hosts infected with Leishmania, Toxoplasma, and Schistosoma, cell and molecular parasitology in which investigators study a range of topics including drug resistance in toxoplasmosis, gene regulation in malaria, and the molecular biology and neurobiology of infective nematode larvae, and population/evolutionary biology with projects which focus on the interaction trematodes with their snail hosts and the population dynamics of parasites of farmed animals.

Parasitology Researchers at the University of Pennsylvania
David Artis Immunology and cell biology of parasitic helminth infections; regulation of innate and adaptive immunity in the gut
Duston Brisson Disease ecology, molecular evolution, microbial ecology/ evolution, host-pathogen interaction
Larry Buxbaum Immunology, immunoparasitology, Leishmania, parasite, IL-10, Fcgamma R, cysteine proteinase
Jay Farrell Cellular immunology and immunopathology of cutaneous and visceral leishmaniasis
Michael Goldschmidt Experimental leishmaniasis
Doron Greenbaum Protease Function, P.falciparum (malaria),
Chemical biology, Proteomics
Robert Greenberg Schistosoma, schistosomiasis, Platyhelminthes, ion channels, calcium channels, multidrug resistance proteins, molecular neurobiology, praziquantel
Christopher Hunter Immunity to Toxoplasma gondii; innate immunity; immunopathology
James Lok Vector-associated parasitisms; experimental filariasis and onchocerciasis
John Murray Molecular motors and mechanochemical transduction
Thomas Nolan Control of Strongyloides stercoralis autoinfection; biology and immunology of helminth infections
Ed Pearce Schistosomiasis; parasitic helminth; Th1/Th2 responses; dendritic cells
Steven Reiner Lymphocyte differentiation and the host response to parasitic disease
David Roos Molecular/cellular parasitology; toxoplasma; plasmodium (malaria); genomics
Gerhard Schad Regulation of nematode growth and development; nematode chemosensory and mechanosensory neurons
Phillip Scott Immune regulation and vaccine development in cutaneous leishmaniasis
Hao Shen Cellular immune responses to intracellular parasites
Gary Smith Mathematical modeling of parasite disease; helminth parasites