What's New

Seminars, Special Events, Research Grants:

Some Research Publications of Note:

Listeria. monocytogenes: Pathogenesis and host response. H. Goldfine and H. Shen, Eds., 2007 Springer, New York, NY. Book
(2007)
Development in motion: helper T cells at work Cell
(2007)
Asymmetric T lymphocyte division in the initiation of adaptive immune responses Science
(2007)
Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection J. Exp. Med. (2007)
Requirement for T-beta in the aberrant differentiation of unhelped memory CD8+ T cells J. Exp. Med. (2007)
Heterogeneity and cell-fate decisions in effector and memory CD8 (+) T cell differentiation during viral infection Immunity (2007)
Molecular signature of CD(+) T cell exhaustion during chronic viral infection Immunity (2007)
Protection againt simian/human immunodeficiency virus (SHIV) 89.6P in macaques after coimmunization with SHIV antigen and IL-15 plasmid PNAS
(2007)
Understanding the benign nature of SIV infection in natural hosts J. Clin. Invest. (2007)
TGF-beta signaling controls embryo development in the parasitic flatworm Schistosoma mansoni PLoS Pathogens (2007)
Worms tame mast cells Nature Med. (2007)
Stimulus-dependent differential regulation in the Escherichia coli PhoQ PhoP system PNAS
(2007)
Poliovirus entry into human brain microvascular cells requires receptor-induced activation of SHP-2 EMBO J.
(2007)
Coxsackievirus entry across epithelial tight junctions requires occluding and the small GTPases Rab34 and Rab5 Cell Host Microbe (2007)
Kaposi's sarcoma herpesvirus-encoded latency-associated nuclear antigen stabilizes intracellular activated Notch by targeting the Sell0 protein PNAS
(2007)
Retroviral integration and human gene therapy J. Clin. Invest. (2007)
Interleukins 27 and 6 induce T cell production of interleukin 10 mediated by transcription factor STAT3 Nature Immunol. (2007)
An autonomous replicating element within the KSHV genome Cell Host & Microbe (2007)
"Viral Pathogenesis and Immunity" 2nd Edition
co-authored by faculty member Neal Nathanson
Book
(2007)
Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing PLoS Pathogens (2007)
V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies. PLoS Pathogens (2007)
Urocanic acid is major chemoattractant for Strongyloides stercoralis PNAS
(2007)
Memory CD8+ T cells are gatekeepers of the lymph node draining the site of viral infection PNAS
(2007)
Epithelial cell-intrinsic IKKß expression regulates intestinal immune homeostasis Nature
(2007)
IL-31-IL-31R interactions negatively regulate type 2 inflammation in the lung J. Exp. Med. (2007)
APOBEC3 inhibits mouse mammary tumour virus replication in vivo Nature
(2007)
Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals J. Exp. Med. (2007)
Ec5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and P53 tumor suppressors PLoS Pathogens (2006)
COPI activity coupled with fatty acid biosynthesis is required for viral replication PLoS Pathogens (2006)
Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid Nature Med. (2006)
Retroviral DNA integration: viral and cellular determinants of target-site selection PLoS Pathogens (2006)
Adeno-associated virus serotype 9 vectors transduce murine alveolar and nasal epithelia and can be readministered. PNAS
(2006)
Vibrio cholerae virulence regulator-coordinated evasion of host immunity PNAS
(2006)
Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract J. Exp. Med. (2006)
Abstract Na+/H+ exchanger type 1 is a receptor for pathogenic subgroup J avian leukosis virus PNAS
(2006)
Host-pathogen interactions in drosophila: new tricks from an old friend Nature Immunol. (2006)
Crystal structure of glycoprotein B from herpes simplex virus 1 Science
(2006)
Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes PNAS
(2006)
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system Nature Immunol. (2006)
Structural basis for specificity in the poxvirus topoisomerase Mol. Cell
(2006)
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1 Cell
(2006)
Virus-induced Abl and Fyn kinase signals permit coxsackievirus entry through epithelial tight junctions Cell
(2006)
"Epstein-Barr Virus" edited by faculty member Erle Robertson Book
(2005)