Keeping viruses in Chk: DNA damage signaling
puts the brakes on transformation
Lilley CE, Weitzman MD. (2011) Cell Host Microbe 8:464-466
Oncogenic viruses infect many cells but rarely lead to tumorigenesis.
In this issue of Cell Host & Microbe, Nikitin et al. describe
how a protective DNA damage response acts to suppress transformation
in the majority of cells latently infected with Epstein-Barr