Selected Publications
Cohen ED, Tian Y, and Morrisey EE. Wnt signaling: an essental regulator of cardiovascular differentation, morphogenesis and progenitor self-renewal. Development (2008)135(5):789-98... (PDF, 1.40mb)
Cohen, E. D., Wang, Z., Lepore, J. J., Lu, M. M., Epstein, J. A., and Morrisey, E. E. Wnt/β-catenin signaling promotes expansion of Isl-1 positive cardiac progenitor cells through regulation of FGF signaling. Journal of Clinical Investigation (2007) 117: 1794-1804... (PDF, 1.46mb)
Oue J, Okubo T, Goldenring JR, Nam KT, Kurotani R, Morrisey EE, Taranova O, Pevny LH, and Hogan BL. Multiple dose-dependent roles for Sox2 in the patterning and differentation of anterior foregut endoderm. Development (2007) 134(13):2521-31... (PDF, 5.73mb)
Shu, W., Lu, M.M., Zhang, Y., Tucker, P.W., Zhou, D., Morrisey, E.E. Foxp2 and Foxp1 cooperatively regulate lung and esophagus development. Development (2007) 134: 1991-2000... (PDF, 6.41mb)
Zhang, Y., Rath, N., Hannenhalli, S., Wang, Z., Cappola, T. P., Kimura, S., Atochina-Vasserman, E., Lu, M. M., Beers, M. F., and Morrisey, E. E. GATA and Nkx factors synergistically regulate tissue specific gene expression and development in vivo. Development (2007) 134: 189-198... (PDF, 3.26mb)
Hannenhalli S, Putt ME, Gilmore JM, Wang J, Parmacek MS, Epstein JA, Morrisey EE, Margulies KB, and Cappola TP. Transcriptional genomics associates FOX transcription factors with human heart failure. Circulation (2007) 114(12):1269-76... (PDF, 435kb)
Shen Q, Wang Y, Dimos JT, Fasano CA Phoenix TN Lemischka IR, Ivanova NB, Stifani S, Morrisey EE, and Temple S. The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells. Nat Neurosci (2006) 9(6):743-51... (PDF, 573kb)
Lepore J. J., Mericko, P. A., Cheng, L., Lu, M. M., Morrisey, E. E., and Parmacek, M. S. GATA-6 regulates semaphorin 3C and is required in cardiac neural crest for cardiovascular morphogenesis. Journal of Clinical Investigation (2006) 116: 929-939... (PDF, 4.07mb)
Lobov, I.B., Rao, S., Carroll, T.J., Vallance, J.E., Ito, M., Ondr, J.K., Kurup, S., Glass, D.A., Pate., M.S., Shu, W., Morrisey, E.E., McMahon, A.P., Karsenty, G. and Lang, R.A. WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature (2005) 437:417-421... (PDF, 567kb)
Shu, W., Guttentag, S., Wang, Z., Andl, T., Ballard, P.W., Lu, M. M., Piccolo, S., Birchmeier, W., Whitsett, J. A., Millar, S. E., and Morrisey, E. E. Wnt/b-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. Developmental Biology (2005) 283:226-239... (PDF,1.07mb)
Shu, W., Cho, J., Jiang, Y., Zhang, M., Haroutunian, V., Weisz, D., Perl, D., Morrisey, E. E., and Buxbaum, J. D. Altered ultrasonic vocalization in mice with a disruption in the Foxp2 gene. Proceedings of the National Academy of Sciences (2005) 102:9643-9648... (PDF, 656kb)
Wang, Z., Shu, W., Lu, M. M., Millar S. E., and Morrisey, E. E. Wnt7b regulates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5. Molecular and Cellular Biology (2005) 25: 5022-5030... (PDF, .97mb)
Li, S., Zhou, D., Lu, M. M., and Morrisey, E. E. Advanced cardiac morphogenesis does not require heart tube fusion. Science. (2004) 305: 1619-1622... (PDF, 812kb)
Wang, B., Weidenfeld, J., Lu, M. M., Maika, S., Kuziel, W. A., Morrisey, E. E., and Tucker, P. W. Foxp1 regulates cardiac outflow tract and endocardial cushion morphogenesis and myocyte proliferation and maturation. Development. (2004) 131: 4477-4487... (PDF, 1.50mb)
Mucenski M.L., Wert S.E., Nation J.M., Loudy D.E., Huelsken J, Birchmeier W, Morrisey E.E., Whitsett JA. beta -catenin is required for specification of proximal/distal cell fate during lung morphogenesis. Journal of Biological Chemistry. (2003) 278: 40231-40238... (PDF, 1.32mb)
Shu, W., Jiang, Y. Q., Lu, M. M., and Morrisey, E. E. Wnt7b regulates mesenchymal proliferation and vascular development in the lung. Development. (2002) 129: 4831-4842... (PDF, 711kb)