medical scientist training program

md-phd program student publications

Plentz R, Park JS, Rhim AD, Abravanel D, Hezel AF, Sharma SV, Gurumurthy S, Deshpande V, Kenific C, Settleman J, Majumder PK, Stanger BZ, Bardeesy N. Inhibition of γ-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma. Gastroenterology. 2009 May;136(5):1741-9.e6.

Huang M, Liu X, Basu SS, Zhang L, Kushman ME, Harvey RG, Blair IA, Penning TM. Metabolism and Disposition of Benzo[a]pyrene-7,8-dione in Human Lung Cells by Liquid Chromatography Tandem Mass Spectrometry: Detection of an Adenine B[a]P-7,8-dione Adduct. Chem Res Toxicol. 2012 In Press.

Basu SS,
Mesaros,C, Gelhaus,SL, Blair, IA. Stable isotope labeling by essential nutrients in cell culture for the preparation of labeled coenzyme A and its thioesters. Anal Chem. 2011 Feb 15;83(4):1363-9.

Basu SS, Blair IA. Rotenone-Mediated Changes in Intracellular Coenzyme A Thioester Levels: Implications for Mitochondrial Dysfunction. Chem Res Toxicol. 2011. 24, 1630-1632

Li P, McElligott S, Bergquist H, Schwartz JS, Doshi JA. Effect of the Medicare Part D coverage gap on medication use among patients with hypertension and hyperlipidemia. Ann Intern M. 2012, Jun 5;156(11):776-84

Puig A, McElligott S, Bergquist H, Doshi JA. Albuterol and levalbuterol use and spending in Medicare beneficiaries with chronic obstructive pulmonary disease. American Journal of Geriatric Pharmacotherapy. 8(6):571-582; 2010.

Carpenter EL, Haglund EA, Mace EM, Deng D, Martinez D, Wood AC, Chow AK, Weiser DA, Belcastro LT, Winter C, Bresler SC, Asgharzadeh S, Seeger RC, Zhao H, Guo R, Christensen JG, Orange JS, Pawel BR, Lemmon MA, Mosse YP. Antibody targeting of anaplastic lymphoma kinase induces cytotoxicity of human neuroblastoma. Oncogene. 2012 Nov 15;31(46):4888.

Bresler SC, Wood AC, Haglund EA, Courtright J, Belcastro LT, Plegaria, JS, Cole K,Toporocskaya Y, Zhao H, Carpenter EL, Christensen JG, Maris JM, Lemmon MA, Mosse YP. Differential inhibitor sensitivity of anaplastic lymphoma kinase variants found in neuroblastoma. Sci Transl Med. 2011 Nov 9;3(108):108ra114.

Epidemiology: General Principles and Practical Research Guidelines. Edited by Van den Broeck J and Brestoff JR, A forthcoming textbook to be published by Springer. Approx. 600 pages with 100 illustrations.

Brestoff JR, Van den Broeck J, Book Review: Epidemiological Research Terms and Concepts. Int J of Epidemiol, 2012. In press.

Van den Broeck J, Brestoff JR, Book Review: Up from Clinical Epidemiology and EBM (Evidence Based Medicine). Eur J Epidemiol, 2012. In press.

Brestoff JR and Van den Broeck J. Global Health and Nutrition. In: Encyclopedia of Global Studies. Ed. Jeurgensmeyer M and Anheier HK. Thousand Oaks: SAGE Reference, 2012. ISBN 9781412964296

Brestoff JR, Perry IJ, Van den Broeck J. Challenging the role of social norms regarding body weight as an explanation for weight and BMI misreporting bias: Development and application of a new approach to examining misreporting bias in surveys. BMC Public Health 11:331, 2011.

Brown SES, Ratcliffe SJ, Kahn JM, Halpern SD, The Epidemiology of Intensive Care Unit Readmissions in the United States. Am J Respir Crit Care Med. 2012 Jan 26.

Young M, Brown SES, Truog R, Halpern SD, Rationing ICU Beds: Disclose or Disguise? Crit Care Med. 2011 Sep 15

Knights D, Kuczynski J, Charlson ES, Zaneveld J, Mozer MC, Collman RG, Bushman FD, Knight R, Kelley ST. Bayesian community-wide culture-independent microbial source tracking. Nature Methods. 2011 Jul 17;8(9):761-3.

Charlson ES, Bittinger K, Haas AR, Fitzgerald AS, Frank I, Yadav A, Bushman FD, Collman RG. Topographical Continuity of Bacterial Populations in the Healthy Human Respiratory Tract. Am J Respir Crit Care Med. 2011 Jun 23.

Yilmaz P, Kottmann R, Field D, Knight R, Cole JR, Amaral-Zettler L, Gilbert JA, Karsch-Mizrachi I, Johnston A, Cochrane G, Vaughan R, Hunter C, Park J, Morrison N, Rocca-Serra P, Sterk P, Arumugam M, Bailey M, Baumgartner L, Birren BW, Blaser MJ, Bonazzi V, Booth T, Bork P, Bushman FD, Buttigieg PL, Chain PS, Charlson ES, Costello EK, Huot-Creasy H, Dawyndt P, DeSantis T, Fierer N, Fuhrman JA, Gallery RE, Gevers D, Gibbs RA, San Gil I, Gonzalez A, Gordon JI, Guralnick R, Hankeln W, Highlander S, Hugenholtz P, Jansson J, Kau AL, Kelley ST, Kennedy J, Knights D, Koren O, Kuczynski J, Kyrpides N, Larsen R, Lauber CL, Legg T, Ley RE, Lozupone CA, Ludwig W, Lyons D, Maguire E, Methé BA, Meyer F, Muegge B, Nakielny S, Nelson KE, Nemergut D, Neufeld JD, Newbold LK, Oliver AE, Pace NR, Palanisamy G, Peplies J, Petrosino J, Proctor L, Pruesse E, Quast C, Raes J, Ratnasingham S, Ravel J, Relman DA, Assunta-Sansone S, Schloss PD, Schriml L, Sinha R, Smith MI, Sodergren E, Spo A, Stombaugh J, Tiedje JM, Ward DV, Weinstock GM, Wendel D, White O, Whiteley A, Wilke A, Wortman JR, Yatsunenko T, Glöckner FO. Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications. Nat Biotechnol. 2011 May;29(5):415-20.

Charlson ES, Chen J, Custers-Allen R, Bittinger K, Li H, Sinha R, Hwang J, Bushman FD, Collman RG. Disordered microbial communities in the upper respiratory tract of cigarette smokers. PLoS One. 2010 Dec 20;5(12 ):e15216.

Bortnick A, Chernova I, Quinn WJ 3rd, Mugnier M, Cancro MP, Allman D. Long-lived plasma cells are induced early in response to T-cell independent and T-cell dependent antigens, J Immunol. 2012 Jun 1;188(11):5389-96

Barnett BE, Ciocca ML, Goenka R, Barnett LG, Wu J, Laufer TM, Burkhardt JK, Cancro MP, Reiner SL. Asymmetric B cell division in the germinal center reaction. Science. 2012 Jan 20;335(6066):342-4

Ciocca ML, Barnett BE, Burkhardt JK, Chang JT, Reiner SL. Cutting edge: Asymmetric memory T cell division in response to re-challenge. J Immunol. 2012 May 1;188(9):4145-8

Chang JT, Ciocca ML, Kinjyo I, Palanivel VR, McClurkin CE, Dejong CS, Mooney EC, Kim JS, Steinel NC, Oliaro J, Yin CC, Florea BI, Overkleeft HS, Berg LJ, Russell SM, Koretzky GA, Jordan MS, Reiner SL. Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division. Immunity. 2011 Apr 22;34(4):492-504.

Hara T, Koh K, Combs DJ, Sehgal A. Post-translational regulation and nuclear entry of TIMELESS and PERIOD are affected in new timeless mutant. J Neurosci, 2011 31(27): 9982-90.

Crayton SH, Elias DR, Al Zaki A, Cheng Z, Tsourkas A. ICP-MS analysis of lanthanide-doped nanoparticles as a non-radiative, multiplex approach to quantify biodistribution and blood clearance. Biomaterials. 2012 Feb;33(5):1509-19

Crayton SH, Tsourkas A. pH-titratable superparamagnetic iron oxide for improved nanoparticle accumulation in acidic tumor microenvironments. ACS Nano. 2011 Dec 27;5(12):9592-601

Cristancho AG, Lazar MA. Forming functional fat: a growing understanding of adipocyte differentiation.Nature Reviews Molecular Cell Biology. 2011 Sep 28;12(11):722-34.

Cristancho AG, Schupp M, Lefterova MI, Cao S, Cohen DM, Chen CS, Steger DJ, Lazar MA. Repressor transcription factor 7-like 1 promotes adipogenic competency in precursor cells. Proceedings of the National Academy of Sciences. 2011 Sep 27;108(39):16271-6.

Schupp M, Cristancho AG, Lefterova MI, Hanniman EA, Briggs ER, Steger DJ, Qatanani M, Curtin JC, Schug J, Ochsner SA, McKenna NJ, Lazar MA. Re-expression of GATA2 cooperates with peroxisome proliferator-activated receptor-gamma depletion to revert the adipocyte phenotype. Journal of Biological Chemistry. 2009 Apr 3;284(14):9458-64.

Schupp M, Lefterova M, Janke J, Leitner K, Cristancho AG, Mullican SE, Szwergold N, Steger DJ, Curtin JC, Kim RJ, Suh M, Albert MR, Engeli S, Gudas LJ, and Lazar MA. Retinol Saturase Promotes Adipogenesis and Is Down-Regulated in Obesity. Proceedings of the National Academy of Sciences. 2009 Jan 27;106(4):1105-10.

Lefterova MI, Zhang Y, Steger DJ, Schupp M, Schug J, Cristancho A, Feng D, Zhuo D, Stoeckert, Jr CJ, Liu XS, and Lazar MA. PPAR and C/EBP Factors Orchestrate Adipocyte Biology Via Adjacent Binding on a Genome-Wide Scale. Genes and Development. 2008 Nov 1;22(21):2941-52.

Moise AR, Domínguez M, Alvarez S, Alvarez R, Schupp M, Cristancho AG, Kiser PD, de Lera AR, Lazar MA, Palczewski K. Stereospecificity of retinol saturase: absolute configuration, synthesis, and biological evaluation of dihydroretinoids. Journal of the American Chemical Society. 2008 Jan 30;130(4):1154-5.

Cross SA, Cook DR, Chi AWS, Vance PJ, Kolson LL, Wong BJ, Jordan-Sciutto KL, Kolson DL. Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophage-mediated neurotoxicity: a novel candidate for HIV neuroprotection. J Immunol. 2011 Nov 15;187(10):5015-25.

Cook DR, Gleichman AJ, Cross SA, Doshi S, Ho W, Jordan-Sciutto KL, Lynch DR, Kolson DL. NMDA receptor modulation by the neuropeptide apelin: implications for excitotoxic injury. J Neurochem. 2011 Sep;118(6):1113-23.

Cook DR*, Cross SA*, Soldan SS, Kolson DL. (2011). NeuroAIDS as an inflammatory disorder. In: The Neurology of AIDS, 3rd Ed. Oxford University Press, Oxford, England. (* these authors contributed equally to the work)

Daye D, Wellen KE. Metabolic Metabolic reprogramming in cancer: unraveling the role of glutamine in tumorigenesis. Semin Cell Dev Biol. 2012 Jun;23(4):362-9

Ashraf AB, Gavenonis S, Daye D, Mies C, Feldman M, Rosen M, Kontos D. A multichannel Markov random field approach for automated segmentation of breast cancer tumor in DCE-MRI data using kinetic observation model. Med Image Comput Comput Assist Interv. 2011;14(Pt 3):546-53.

Tilton JC, Wilen CB, Didigu CA, Sinha R, Harrison JE, Agrawal-Gamse C, Henning EA, Bushman FD, Martin JN, Deeks SG, Doms RW. A maraviroc-resistant HIV-1 with narrow cross-resistance to other CCR5 antagonists depends on both N-terminal and extracellular loop domains of drug-bound CCR5. J Virol. 2010 Oct;84(20):10863-76

He J, Li H, Edmondson AC, Rader DJ, Li M.. A Gaussian copula approach for the analysis of secondary phenotypes in case-control genetic association studies. Biostatistics. 2012 Jul;13(3):497-508

Wang K, Edmondson AC, Li M, Wilensky R, Matthai W, Qasim A, Daveney J, Burnett MS, Pichard AD, Kent KM, Satler L, Lindsay JM, Waksman R, Knouff CW, Waterworth DM, Walker MC, Mooser V, Epstein SE, Grant SF, Reilly MP, Hakonarson H, Rader DJ. Pathway-wide association studies implicate multiple sterol transport and metabolism genes in regulating HDL cholesterol levels. Front Genet. 2011;2:41

Khetarpal SA*, Edmondson AC*, Raghavan A, Neeli H, Jin W, Badellino KO, Cupples LA, Demissie S, Manning A, DerOhannessian S, Wolfe ML, Kathiresan S, Rader DJ. Mining the LIPG Allelic Spectrum Reveals the Contribution of Rare and Common Regulatory Variants to HDL Cholesterol. PLoS Genet. 2011. 7:e1002393.

Edmondson AC, Braund PS, Stylianou IM, Khera AV, Nelson CP, Wolfe ML, DerOhannessian SL, Keating BJ, Qu L, He J, Tobin MD,Tomaszewski M, Baumert J, Klopp N, Doring A, Thorand B, Li M, Reilly MP, Koenig W, Samani NJ, Rader DJ. Dense genotyping of candidate gene loci identifies variants associated with high-density lipoprotein cholesterol. Circ Cardiovasc Genet. 2011. 4:145-155.

He J, Wang K, Edmondson AC, Rader DJ, Li C, Li M. Gene-based Interaction Analysis by Incorporating External Linkage Disequilibrium Information. Eur J Hum Genet. 2011.19:164-172.

Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S, Chasman DI, Willer CJ, Johansen CT, Fouchier SW, Isaacs A, Peloso GM, Barbalic M, Ricketts SL, Bis JC, Aulchenko YS, Thorleifsson G, Feitosa MF, Chambers J, Orho-Melander M, Melander O, Johnson T, Li X, Guo X, Li M, Shin Cho Y, Jin Go M, Jin Kim Y, Lee JY, Park T, Kim K, Sim X, Twee-Hee Ong R, Croteau-Chonka DC, Lange LA, Smith JD, Song K, Hua Zhao J, Yuan X, Luan J, Lamina C, Ziegler A, Zhang W, Zee RY, Wright AF, Witteman JC, Wilson JF, Willemsen G, Wichmann HE, Whitfield JB, Waterworth DM, Wareham NJ, Waeber G, Vollenweider P, Voight BF, Vitart V, Uitterlinden AG, Uda M, Tuomilehto J, Thompson JR, Tanaka T, Surakka I, Stringham HM, Spector TD, Soranzo N, Smit JH, Sinisalo J, Silander K, Sijbrands EJ, Scuteri A, Scott J, Schlessinger D, Sanna S, Salomaa V, Saharinen J, Sabatti C, Ruokonen A, Rudan I, Rose LM, Roberts R, Rieder M, Psaty BM, Pramstaller PP, Pichler I, Perola M, Penninx BW, Pedersen NL, Pattaro C, Parker AN, Pare G, Oostra BA, O'Donnell CJ, Nieminen MS, Nickerson DA, Montgomery GW, Meitinger T, McPherson R, McCarthy MI, McArdle W, Masson D, Martin NG, Marroni F, Mangino M, Magnusson PK, Lucas G, Luben R, Loos RJ, Lokki ML, Lettre G, Langenberg C, Launer LJ, Lakatta EG, Laaksonen R, Kyvik KO, Kronenberg F, Konig IR, Khaw KT, Kaprio J, Kaplan LM, Johansson A, Jarvelin MR, Cecile J W Janssens A, Ingelsson E, Igl W, Kees Hovingh G, Hottenga JJ, Hofman A, Hicks AA, Hengstenberg C, Heid IM, Hayward C, Havulinna AS, Hastie ND, Harris TB, Haritunians T, Hall AS, Gyllensten U, Guiducci C, Groop LC, Gonzalez E, Gieger C, Freimer NB, Ferrucci L, Erdmann J, Elliott P, Ejebe KG, Doring A, Dominiczak AF, Demissie S, Deloukas P, de Geus EJ, de Faire U, Crawford G, Collins FS, Chen YD, Caulfield MJ, Campbell H, Burtt NP, Bonnycastle LL, Boomsma DI, Boekholdt SM, Bergman RN, Barroso I, Bandinelli S, Ballantyne CM, Assimes TL, Quertermous T, Altshuler D, Seielstad M, Wong TY, Tai ES, Feranil AB, Kuzawa CW, Adair LS, Taylor HA Jr, Borecki IB, Gabriel SB, Wilson JG, Holm H, Thorsteinsdottir U, Gudnason V, Krauss RM, Mohlke KL, Ordovas JM, Munroe PB, Kooner JS, Tall AR, Hegele RA, Kastelein JJ, Schadt EE, Rotter JI, Boerwinkle E, Strachan DP, Mooser V, Stefansson K, Reilly MP, Samani NJ, Schunkert H, Cupples LA, Sandhu MS, Ridker PM, Rader DJ, van Duijn CM, Peltonen L, Abecasis GR, Boehnke M, Kathiresan S. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010. 466:707-713.

Brown RJ, Edmondson AC, Griffon N, Hill TB, Fuki IV, Badellino KO, Li M, Wolfe ML, Reilly MP, Rader DJ. A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis. J Lipid Res. 2009 Sep;50(9):1910-6.

Jensen MK, Rimm EB, Mukamal KJ, Edmondson AC, Rader DJ, Vogel U, Tjonneland A, Sorensen TI, Schmidt EB, Overvad K. The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations. Eur Heart J. 2009. 30:1584-1589.

Edmondson AC, Brown RJ, Kathiresan S, Cupples LA, Demissie S, Manning AK, Jensen MK, Rimm EB, Wang J, Rodrigues A, Bamba V, Khetarpal SA, Wolfe ML, DerOhannessian S, Li M, Reilly MP, Aberle J, Evans D, Hegele RA, Rader DJ. Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. J Clin Invest. 2009.119:1042-50.

Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC, Grant SF, Farlow DN, Chandrupatla HR, Hansen M, Ajmal S, Papanicolaou GJ, Guo Y, Li M, Derohannessian S, de Bakker PI, Bailey SD, Montpetit A, Edmondson AC, Taylor K, Gai X, Wang SS, Fornage M, Shaikh T, Groop L, Boehnke M, Hall AS, Hattersley AT, Frackelton E, Patterson N, Chiang CW, Kim CE, Fabsitz RR, Ouwehand W, Price AL, Munroe P, Caulfield M, Drake T, Boerwinkle E, Reich D, Whitehead AS, Cappola TP, Samani NJ, Lusis AJ, Schadt E, Wilson JG, Koenig W, McCarthy MI, Kathiresan S, Gabriel SB, Hakonarson H, Anand SS, Reilly M, Engert JC, Nickerson DA, Rader DJ, Hirschhorn JN, Fitzgerald GA. Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS ONE 2008. 3:e3583.

Edmondson AC and Rader DJ. Genome-Wide Approaches to Finding Novel Genes for Lipid Traits: the Start of a Long Road. Circ Cardiovasc Genet. 2008.1:3-6.

Finkelman BS, Rubinstein WS, Friedman S, Friebel TM, Rebbeck TR, et al, for the PROSE Consortium. Breast and Ovarian Cancer Risk and Risk Reduction in Jewish BRCA1/2 Mutation Carriers. J Clin Oncol. 2012 Apr; 30(12): 1321-28.

Finkelman BS
, Gage BF, Johnson JA, Brensinger CM, Kimmel SE. Genetic Warfarin Dosing: Tables vs. Algorithms. J Am Coll Cardiol. 2011 Feb 1;57(5):612-8.

Zhang Z, Kofonow JM, Finkelman BS, Doghramji L, Chiu AG, Kennedy DW, Cohen NA, Palmer JN. Clinical factors associated with bacterial biofilm formation in chronic rhinosinusitis. Otolaryngol Head Neck Surg. 2011 Mar;144(3):457-62.

Zhang Z, Linkin DR, Finkelman BS, O'Malley BW Jr, Thaler ER, Doghramji L, Kennedy DW, Cohen NA, Palmer JN. Asthma and biofilm-forming bacteria are independently associated with revision sinus surgeries for chronic rhinosinusitis. J Allergy Clin Immunol. 2011 Jul;128(1):221-223.e1.

Schelleman H, Brensinger CM, Chen J, Finkelman BS, Rieder MJ, Kimmel SE. (2010) New genetic variant that might improve warfarin dose prediction in African Americans. Br J Clin Pharmacol. 2010 Sep;70(3):393-9.

Friedman AB, Becker N. Understanding the Individual Mandate's SCOTUS Pivot Points. LDI Health Economist. April 2012.

Ezzati M, Horwitz ME, Thomas DS, Friedman AB, Roach R, Clark T, Murray CJ, Honigman B. Altitude, life expectancy and mortality from ischaemic heart disease, stroke, COPD and cancers: national population-based analysis of US counties. J Epidemiol Community Health. 2012 Jul;66(7):e17. doi: 10.1136/jech.2010.112938

Dionisio KL, Rooney MS, Arku RE, Friedman AB, Hughes AF, Vallarino J, Agyei-Mensah S, Spengler JD, Ezzati M. Within-neighborhood patterns and sources of particle pollution: mobile monitoring and geographic information system analysis in four communities in Accra, Ghana. Environmental Health Perspectives 2010. 118(5):607-13.

Gandal MJ, Edgar JC, Klook K, Siegel SJ. Gamma synchrony: towards a translational biomarker for the treatment-resistant symptoms of schizophrenia. Neuropharmacology. 2012 Mar;62(3):1504-18. doi: 10.1016/j.neuropharm.2011.02.007

Gandal MJ
, Sisti J, Klook K, Leitman V, Liang Y, Thieu T, Ortinski P, Pierce CR, Saunders J, Anderson R, Ambler L, Jonak G, Gur R, Carlson GC, Siegel SJ. GABAB-mediated rescue of altered excitatory-inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction. Transl Psychiatry. 2012 Jul 17;2:e142.

Gandal MJ, Anderson R, Billingslea E, Roberts TP, Carlson GC, Siegel SJ Mice with reduced NMDA receptor expression: more consistent with autism than schizophrenia? Genes Brain Behav. 2012 Aug;11(6):740-50

Saunders J, Gandal MJ, Siegel SJ NMDA antagonists recreate signal-to-noise ratio and timing perturbations present in schizophrenia. Neurobiol Dis. 2012 Apr;46(1):93-100

Liao W,Gandal MJ, Ehrlichman RS, Siegel SJ, Carlson GC. MeCP2+/- mouse model of RTT reproduces auditory phenotypes associated with Rett syndrome and replicate select EEG endophenotypes of autism spectrum disorder. Neurobiol Dis. 2012 Apr;46(1):88-92

Gandal MJ,Edgar JC, Klook K, Siegel SJ. Gamma synchrony: towards a translational biomarker for the treatment-resistant symptoms of schizophrenia. Neuropharmacology. 2012 Mar;62(3):1504-18.

Carlson GC, Talbot K, Halene TB,Gandal MJ, Kazi HA, Schlosser L, Gur RE, Arnold SE, Siegel SJ Dysbindin-1 mutant mice implicate reduced parvalbumin-cell mediated inhibition as a final common disease mechanism in schizophrenia. 2011 PNAS. 108(43):E962-70.

Mehta MM*, Gandal MJ*, Siegel SJ. mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism. PLoS One. 2011;6(10):e26077. *Equal contribution.

Lazarewicz MT, Ehrlichamn RS, Maxwell CR,Gandal MJ, Siegel SJ, Finkel LH. Ketamine modulates theta and gamma oscillations. J Cogn Neurosci.2010 22(7): 1452-64.

Amann LC, Gandal MJ, Lin R, Liang Y, Siegel SJ. In vitro in vivo correlations of scalable PLGA / risperidone implants for the treatment of schizophrenia.Pharm Res.2010 27(8):1730-7

Amann LC, Gandal MJ, Halene TB, Ehrlichman RS, White SL, McCarren HS, Siegel SJ. Mouse behavioral endophenotypes for schizophrenia. Brain Res Bull. 2010 83(3-4):147-61

Roberts TPL, Khan S, Rey M, Monroe J, Cannon K, Blaskey L, Woldoff S, Qasmieh S, Gandal M, Schmidt G, Zarnow DM, Levy SE, Edgar JC. MEG Detection of Delayed Auditory Evoked Responses in Autism Spectrum Disorders: Towards an Imaging Biomarker for Autism. Autism Res2010 3(1):8-18.

Gandal MJ, Edgar JC, Ehrlichman RS, Mehta M, Roberts TP, Siegel SJ. Validating gamma oscillations and delayed auditory responses as translational biomarkers of autism. Biol Psychiatry 2010 68(12):1100-6

Gandal MJ, Ehrlichman RS, Siegel SJ. A novel electrophysiological model of chemotherapy induced cognitive impairment in mice. Neuroscience. 2008157(1): 95-104

Ehrlichman RS,Gandal MJ, Maxwell CR, Lazarewicz M, Finkel LH, Contreras D, Turetsky BI, Siegel SJ N-methyl-D-aspartate receptor antagonist induced frequency oscillations in mice recreates the pattern of electrophysiological deficits in schizophrenia.Neuroscience2008 158(2): 705-12.

Gordon SM, Chaix J, Rupp LJ, Wu J, Madera S, Sun JC, Lindsten T, Reiner SL. The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation. Immunity 2012 36, 55­67.

Qui HZ, Hagymasi AT, Bandyopadhyay S, St Rose MC, Ramanarasimhaiah R, Ménoret A, Mittler RS, Gordon SM, Reiner SL, Vella AT, Adler AJ. CD134 plus CD137 dual costimulation induces Eomesodermin in CD4 T cells to program cytotoxic Th1 differentiation. J Immunol 2011 187, 3555-3564.

Gordon SM, Carty SA, Kim JS, Zou T, Smith-Garvin J, Alonzo ES, Haimm E, Sant'Angelo DB, Koretzky GA, Reiner SL, Jordan MS. Requirements for eomesodermin and promyelocytic leukemia zinc finger in the development of innate-like CD8+ T cells. J Immunol 2011 186, 4573-4578.

Kinjyo I, Gordon SM, Intlekofer AM, Dowdell K, Mooney EC, Caricchio R, Grupp SA, Teachey DT, Rao VK, Lindsten T, Reiner SL. Cutting edge: Lymphoproliferation caused by Fas deficiency is dependent on the transcription factor eomesodermin. J Immunol. 2010 Dec 15;185(12):7151-5.

Banerjee A, Gordon SM, Intlekofer AM, Paley MA, Mooney EC, Lindsten T, Wherry EJ, Reiner SL. Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche. J Immunol 2010 185, 4988-4992.

Intlekofer AM, Banerjee A, Takemoto N, Gordon SM, Dejong CS, Shin H, Hunter CA, Wherry EJ, Lindsten T, Reiner SL. Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin. Science 2008 321, 408-411.

Jamiolkowski RM, Guo LY, Li YR, Shaffer SM, Naji A. Islet transplantation in type I diabetes mellitus. Yale J Biol Med. 2012 Mar; 85(1):37-43.

Shen CJ, Raghavan S, Xu Z, Baranski JD, Yu X, Wozniak MA, Miller JS, Gupta M, Buckbinder L, Chen CS. Decreased cell adhesion promotes angiogenesis in a Pyk2-dependent manner. Exp Cell Res. 2011 Aug 1;317(13):1860-71.

Anokye-Danso F, Trivedi CM, Juhr D, Gupta M, Cui Z, Tian Y, Zhang Y, Yang W, Gruber PJ, Epstein JA, Morrisey EE. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell. 2011 Apr 8;8(4):376-88.

Zlotoff DA, Zhang SL, De Obaldia ME, Hess PR, Todd SP, Logan TD, Bhandoola A. Delivery of progenitors to the thymus limits T-lineage reconstitution after bone marrow transplantation. Blood. 2011 Aug 18;118(7):1962-70.

Bertozzi CC, Schmaier AA, Mericko P, Hess PR, Zou Z, Chen M, Chen C, Xu B, Lu M, Zhou D, Sebzda E, Santore MT, Merianos DJ, Stadtfeld M, Flake AW, Graf T, Skoda R, Maltzman JS, Koretzky GA, Kahn ML. Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling. Blood. 2010 Jul 29;116(4):661-70.

Signarvic RS, Cierniewska A, Stalker TJ, Fong KP, Chatterjee MS, Hess PR, Ma P, Diamond SL, Neubig RR, Brass LF. RGS/Gi2alpha interactions modulate platelet accumulation and thrombus formation at sites of vascular injury. Blood. 2010 Dec 23;116(26):6092-100.

Bertozzi CC, Hess PR, Kahn ML. Platelets: covert regulators of lymphatic development. Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2368-71.

Hill DA, Siracusa MC, Abt MC, Kim BS, Kobuley D, Kubo M, Kambayashi T, Larosa DF, Renner ED, Orange JS, Bushman FD, Artis D. Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation. Nat Med. 2012 Mar 25;18(4):538-46.

Carvalho LP, Petritus PM, Trochtenberg AL, Zaph C, Hill DA, Artis D, Scott P Lymph node hypertrophy following Leishmania major infection is dependent on TLR9. J Immunol. 2012 Feb 1;188(3):1394-401.

Siracusa MC, Saenz SA, Hill DA, Kim BS, Headley MB, Doering TA, Wherry EJ, Jessup HK, Siegel LA, Kambayashi T, Dudek EC, Kubo M, Cianferoni A, Spergel JM, Ziegler SF, Comeau MR, Artis D TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation. Nature. 2011 Aug 14;477(7363):229-33

Hill DA, Artis D. Intestinal bacteria and the regulation of immune cell homeostasis. Annual Reviews of Immunology. 2010 Apr;28:623-67. PMID: 20192812.

Hill DA, Hoffmann C, Abt MC, Du Y, Kobuley D, Kirn TJ, Bushman FD, Artis D Metagenomic analyses reveal antibiotic-induced temporal and spatial changes in intestinal microbiota with associated alterations in immune cell homeostasis. Mucosal Immunol. 2010 Mar;3(2):148-58

Hill DA, Artis D. Maintaining diplomatic relations between mammals and beneficial microbial communities. Science Signaling. 2009 Nov;2(98):77-79.

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Strong A, Rader DJ. Clinical Implications of Lipid Genetics for Cardiovascular Disease. Curr Cardiovasc Risk Rep. 2010 Oct;4(6):461-468.

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Kambayashi T, Allenspach E, Chang J, Zou T, Shoag J, Reiner S, Caton A, Koretzky G. Inducible MHC class II expression by mast cells supports effector and regulatory T cell activation. J Immunol. 2009 Apr 15;182(8):4686-95.

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Kambayashi T, Baranski J, Baker R, Zou T, Allenspach E, Shoag J, Jones P, Koretzky G. Indirect involvement of allergen-captured mast cells in antigen presentation. Blood. 2008 Feb 1;111(3):1489-96.