What's New in the MD-PhD Program?
Below is a list of recent and upcoming dissertation defenses:
2009-2010 DEFENSES to date:
December
Amy Tsou (CAMB)
December 4, 12:00, 209 Johnson Pavilion
Title: Novel Targets and a Cofactor for the Vibrio Cholerae Quorum Sensing Transcriptional Regulator, HapR
advisor: Dr. Jun (Jay) Zhu
Alex Chavez (CAMB)
December 7, 10:30, 14th floor BRB
Title: Novel Roles for the SMC5/6 Complex and the DNA Helicase MPH1 in Template Switch
advisor: Dr. Brad Johnson
Shetal Patel (CAMB)
December 10, 10:30, BRB Auditorium
Title: Functional Analysis of the Cdk7/cyclin H/Mat1 Complex in Mouse Embryonic Stem Cells and Embryos
advisor: Dr. Celeste Simon
Brett McCray (Neuroscience)
December 14, 3:30, location TBA
Title: Mutations in Rab7 That Cause Axonal Degeneration Result in Unregulated Nucleotide Exchange and Inappropriate Activation
advisor: Dr. J Paul Taylor
Chiu-yu Chen (Bioengineering)
December 15, 12:00, BRB Auditorium
Title: TBA
advisor: Dr. Mark Kahn
November
Uma
Sachdeva (CAMB)
November 5, 1:00pm,
Dunlop Auditorium (Stemmler)
Title: The circadian clock as a sensor of cell metabolic state: Interactions between nutrients, growth factors,
and the mammalian clock machinery
advisor: Dr. Craig Thompson
Defne Amado (Neuroscience)
November 20, 2:00pm, Barchi Library (140 John Morgan Bldg)
Title: Gene therapy in the retina: exploring neurotrophic treatment and readminstration in Retinal Disease
advisor: Dr. Jean Bennett
Ksenia Orlova (Neuroscience)
November 24, 3:00pm, Barchi Library (140 John Morgan Bldg)
Title: The function of STRADa during corticogenenesis: Insights into the neuropathogenesis of ocal Cortical Dysplasias
advisor: Dr. Peter Crino
David Wise (CAMB)
November 30, 2:00pm, CRB Austrian Auditorium
Title: TBD
advisor: Dr. Craig Thompson
October
Anup Sharma (Neuroscience)
October 27, 1:00pm, Barchi Library (140 John Morgan Bldg)
Title: A neurotoxic phosphoform of ELK-1 is implicated in neurodegenerative disease
advisor: Dr. Jim Eberwine
September
Matt Buas (CAMB)
September 16, 3:30pm, 251 BRB
Mechanisms of Notch-Mediated Inhibition of Skeletal Myogenesis
advisor: Dr. Tom Kadesch
Kunal Patel (CAMB)
September 21, 2:30pm Class of 62 Auditorium
Coxsackievirus Entry into Nonpolarized Cells
advisor: Dr. Jeff Bergelson
Alexei Polishchuk (BMB)
Sept 23, 11:00am, 255 Anatomy Chemistry
Structure-based mechanism of proton transport through the influenza A/M2 protein
advisor: Dr. Bill DeGrado
2008-2009 DEFENSES to date:
June
Priya Dedhia (immunology)
June 12, 2:00pm, CRB Austrian Auditorium
The role of Tribbles in myeloid differentiation and transformation
advisor: Dr. Warren Pear
May
Anil Panigrahi (CAMB)
May 1, 2:00pm, BRB Auditorium
RS Rearrangement: Observations and Implications from a Novel Assay of B Cell Tolerance
advisor: Dr. Nina Luning Prak
December
Matthew Bevers (Neuroscience)
December 1, 1:00pm, Barchi Library
Role of calpain isoforms in acute brain injury
advisor: Dr. Robert Neumar
Benjamin Kleaveland (CAMB)
December 1, 2:00pm, Reunion Auditorium
Regulation of Cardiovascular Organ Formation and Integrity by
the Heart of Glass Receptor-Cerebral Cavernous Malformation Pathway
advisor: Dr. Mark Kahn
Jennifer Oliver-Krasinski (Pharm)
December 1, 2:30pm, Class of ‘62
Novel roles for Pdx1 in the endocrine pancreas
advisor: Dr. Doris Stoffers
Marisa Juntilla (Immunology)
December 1, 3:00pm, BRB Auditorium
Akt signaling maintains survival and proliferation in immature T cells and hematopoietic stem cells.
advisor: Dr. Gary Koretzky
Larry Bish (CAMB)
December 2, 3:00pm, CRB Austrian Auditorium
Myostatin regulation and function in the heart Location and Time
advisor: Dr. H. Lee Sweeney
Matt Culyba (CAMB)
December 2, 12:00pm, Hill 131
Catalysis by the poxvirus Holliday junction resolving enzyme
advisor: Dr. Frederic D. Bushman
Jason Watts (CAMB)
December 15, 3:00pm, Location - TBD
FoxA Pioneer Factor: Genetic Competence and Epigenetic Restriction
advisor: Dr. Ken Zaret
November
Josh Gruber (CAMB)
November 3, 3:00pm, Class of '62
Ars2 links the RNA interference pathway to cellular proliferation
advisor: Dr. Craig Thompson
Andy McClelland (Neuroscience)
November 10, 11:30am, Barchi Library (140 John Morgan)
The ephrin-B family of receptor tyrosine kinase ligands in CNS synapse development
advisor: Dr. Matthew Dalva
Amol Navathe (Health Care Systems)
November 14, 9:00am, Chesnut Room, Colonial Penn Center (3641 Locust Walk)
The formation of surgeon peer reputation and its effect on technology adoption
advisor: Dr. Mark Pauly
Mira Sachdeva (CAMB)
November 17, 3:00pm, Reunion Auditorium
Title - TBD
advisor: Dr. Doris Stoffers
Ali Harrist (Neuroscience)
November 20, 3:00pm, Wood Room (John Morgan Building)
Annexin 2 interacts with HIV-1 Gag at phosphatidylinositol (4,5) bisphosphate-containing lipid rafts and increases viral production
advisor: Dr. Francisco Gonzalez-Scarano
Stephanie Eucker (Bioengineering)
November 25, 9:00am, 337 Towne Building
Title - TBD
advisor: Dr. Susan Margulies
October
Marie Guerraty (Bioengineering)
October 9, 1:00pm, Vagelos 2000
Aortic Valve Endothelial Phenotypes during Hypercholesterolemia
advisor: Dr. Peter F. Davies
Martina Lefterova (CAMB)
October 15, 1:00pm, BRB Auditorium
Genome-wide Orchestration of Adipocyte Biology by PPARg and C/EBP
advisor: Dr. Mitchell A. Lazar
Eric Mellon (BMB)
October 23, 3:30pm, Johnson Foundation Library (248 Anatomy-Chemistry)
The regional cerebral metabolic rate of oxygen consumption with proton
detected
17O MRI during precision 17O2 inhalation in swine
advisor: Dr. Ravinder Reddy
Meredith Miller (Pharmacology)
October 29, 2:00pm, Johnson Foundation Library (248 Anatomy-Chemistry)
Small molecule inhibitors of integrin α2β1(alpha2beta1) that prevent pathological thrombus formation via an allosteric mechanism
advisor: Dr. William F DeGrado
September
Le-Ben Wan (CAMB)
September 4, 2:00pm, 251 BRB
Maternal Depletion of CTCF Reveals Multiple Functions In Transcription and Development
advisor: Dr. Marisa Bartolomei
Simone Stalling (Bioengineering)
September 10, 2:00pm, 337 Towne Building
Biological Approaches to Connective Tissue Repair
advisor:
Dr. Steven B. Nicoll
Michael Avissar (Neuroscience)
September 12, 10:00am, Barchi Library (140 JMB)
The Reliability and Precision of Auditory Nerve Reponses
advisors: Dr. Thomas Parsons and Dr. Jim Saunders
Eric Allenspach (Immunology)
September 12, 1:00pm, TBD
Dendritic Cell Subsets in the Regulation of CD4+ T Cell Immune Responses
advisor: Dr. Terri Laufer
Elise Carpenter
(History and Sociology of Science)
September 12, 2:00pm, Cohen/Logan 392
The Social Practice of HIV Drug Therapy in Botswana, 2002-2004:
Experts, Bureaucrats, and Health Care Providers
advisor: Dr. Steven Feierman
AUGUST
Sarah Choi (CAMB)
August 12, 1:00pm, Class of '62 in JMB
Insulin Regulates Adipocyte Lipolysis via a Compartmentalized AKT-Independent Signaling Pathway
advisor: Dr. Morrie Birnbaum
JULY
Vikram Palanivel (Immunology)
July 22, 2:00pm, Class of '62 in JMB
The One and The Many: Generating Diversity during Adaptive Immunity
advisor: Dr. Steve Reiner
2007-2008 DEFENSES
JANUARY
Matt Scharf (Neuroscience)
January 3, 2:00pm, Barchi Library (140 John Morgan Bldg.)
Role of AMPH in Sleep-Wake
advisor: Dr. Allan Pack
DECEMBER
Jing Wang (CAMB)
December 3, 1:30pm, CRB Austrian Auditorium
"Regulation of circadian rhythm and adipogenesis by the nuclear receptor Rev-erb alpha"
advisor: Dr. Mitch Lazar
Prin Amorapanth (Neuroscience)
Dec 3 - 1:30pm, Barchi Library (140 John Morgan Bldg.)
Where Are They? The Neural Systems Underlying the Language of Space
mentor: Dr. Anjan Chatterjee
Tamar Gur (Neuroscience)
December 4, 10am, Barchi Library (140 John Morgan)
"The Role of CREB Family Transcription Factors in Depression, Anxiety, and Antidepressant Response"
advisor: Dr. Julie Blendy
NOVEMBER
Neel Singhal (Neuroscience)
November 2, 2:30, 140 John Morgan (Barchi Library)
"The role of resistin in the CNS regulation of glucose and energy homeostasis"
advisor: Dr. Rex Ahima
John Gordan (CAMB)
November 20, 2 pm, JMB Class of '62
" HIF-1alpha and HIF-2alpha have antagonistic effects on c-Myc: implications for
normal and transformed cell proliferation"
advisor: Dr. Celeste Simon
Andy Intlekofer (Immunology)
November 26, 3:00, BRB auditorium
Transcriptional control of CD8+ T cell differentiation: a tale of two T-box factors
advisor: Dr. Steve Reiner
OCTOBER
Frances High (CAMB)
Oct. 4, 1:15pm., CRB Austrian Aud
"Notch Signaling in Cardiac Development"
advisor: Dr. Jon Epstein
Dexter Hadley (GCB)
Oct. 8, 2:00pm, CRB auditorium
Genome-scale annotation of genetic factors underlying neurotransmission & neuropsychiatric disease
advisors: Dr. Junhyong Kim and Dr. Maja Bucan
Doug Lin (CAMB)
Oct. 26 at 2:00pm in BRB auditorium
"Interplay between SCF and CDK complexes in the control of cellular proliferation"
advisor: Dr. J. Alan Diehl
SEPTEMBER
Andrew Trister (Bioengineering)
Sept. 18, 10:30am, in Wu and Chen Auditorium in Levine Hall
"Nanoscale particle binding in silico: Hiv docking and multivalent recruitment under flow"
advisor: Dr. Dan Hammer
Matt Kayser (Neuroscience)
Sept.. 20, 10:00am, 140 John Morgan Bldg.
"EphB Receptors Direct Formation of a Subset of CNS Excitatory Synapses"
advisor: Dr. Matthew Dalva
2006-2007 DEFENSES
AUGUST
Jennifer Orthmann Murphy (Neuroscience)
August 29, 1:30pm Barchi Library (140 JMB)
"The role of Cx47 in gap junction coupling between astrocytes and oligodendrocytes"
advisor: Dr. Steve Scherer
MAY
Pallavi Gopal (Neuroscience)
May 21, 10am, Barchi Library (140 John Morgan)
"Guiding non-radial cell migration"
advisor: Dr. Jeff Golden
FEBRUARY
Tina Franklin-Dumont (CAMB)
Wednesday, Feb 7th, 10am, Class of '62, John Morgan Bldg.
"Counting up off schedule: Investigating the timing of developmental transitions in the Drosophila testis"
advisor: Dr. Steve DiNardo
NOVEMBER
John Northrop (CAMB)
November 2, 2:00pm, in 209 Johnson Pav
"CD4 T help dependent epigenetic remodeling in memory CD8 T cells"
advisor: Dr. Hao Shen
OCTOBER
Daria (Dasha) Babushok (CAMB)
Oct 31, 2006, 2pm, Class of 62 Auditorium, John Morgan Bldg.
"Role of Line-1 retrotransposon in genome evolution: mechanisms of L1 integration and L1-mediated creation of new genes"
advisor: Dr. Haig Kazazian
SEPTEMBER
Melissa Middleton (Immunology)
Sept 8, 2pm, Austrian Auditorium, CRB
"12/15-lipoxygenase and the myeloid cell: A chronicle of oxidation, inflammation, and leukemogenesis"
advisor: Dr. Ellen Pure
P. Peter Ghoroghchian (Bioengineering)
Sept 8, 3:00pm, Wu and Chen Auditorium, Levine Hall (3330 Walnut)
"Emissive Polymer Vesicles: Soft Nanoscale Probes for in vivo Optical Imaging"
advisor: Dr. Dan Hammer and Dr. Michael Therin
Ben Schwarz (Immunology)
Sept 11, 11:00, 251 BRB II/III
"Trafficking from the bone marrow to the thymus: a prerequisite for T lymphopoiesis"
advisor: Dr. Avinash Bhandoola
2005-2006 DEFENSES
JUNE
Michael Buckstein (CAMB)
Thursday, June 15, 1:00 pm, 252 BRB 11/111
"A Novel HPLC Based Approach to Characterizing and Quantitating Nucleotide Pools in Bacteria"
advisor: Dr. Harvey Rubin
Darren Hess (Neuroscience)
June 2, 9am, Barchi Library (140 John Morgan Bldg).
"The role of neurotrophin signaling in development and maintenance of neuromuscular synapses"
advisor: Dr. Rita Balice Gordon
Tessa Sundaram (Bioengineering)
June 5, 2:00pm, 1412 BRB 11/111
"Quantitative Regional Assessment of Pulmonary Parenchymal Dynamics Using Image Registration and Analysis Techniques"
advisor: Dr. Jim Gee
MAY
Evan Ray (CAMB)
May 5, 3:00pm, B-400 Richards
"Intracellular Cations Modulate Kv Channel Recovery From Slow Inactivation"
advisor: Dr. Carol Deutsch
APRIL
Ben Olenchock (Immunology)
Tuesday, April 25, 2006 1:00-3:00 PM JMB Class of '62 Auditorium
"Regulated Diacylglycerol Metabolism During Antigen Receptor Stimulation of T Cells and Mast Cells"
advisor: Dr. Gary Koretzky
MARCH
Gina Clemens (Immunology)
March 20, 2pm, Austrian Auditorium, CRB
"Tyrosine Kinase-Associated Receptor Signaling in Neutrophils: Regulation by Adaptor Molecules In Vitro and In Vivo"
advisor: Dr. Gary Koretzky
Aaron Nelson (CAMB)
March 21, 1pm, Class of '62, John Morgan Building
" Local Mucosal Responses to Bacterial Colonization"
advisor: Dr. Jeff Weiser
FEBRUARY
Laila Dadvand (Neuroscience)
Feb 6, 1:00, 140 John Morgan Bldg, JMB
"Divergent Effect of Sleep on the Loss and Recovery of Deprived Eye Responses in the Developing Visual Cortex"
advisor: Dr. Michael Stryker (secondary advisor, Dr. Marcos Frank)
Joanne Jang (CAMB)
Feb 16, 2:00, Reunion Auditorium, JMB
"The Contribution of Ras to MYC and Wnt-induced Tumor Progression"
advisor: Dr. Lewis Chodosh
JANUARY
Lara Wine Lee (Neuroscience)
Jan 19th, 1:30, Abramson Bldg., 7th Floor Center Conference Room
"The Role of Signaling through BMP Type I Receptors in Central Nervous System Development"
advisor: Dr. E. Bryan Crenshaw
DECEMBER
Evan Farkash (Immunology)
Dec 2, 10:00, Reunion Hall, JMB
"Keeping L1s in Line: Genomic Defenses Against Retrotransposition"
advisor: Dr. Nina Luning Prak
Chris Vakoc (CAMB)
Dec 7, 1:30, Austrian Auditorium, CRB
"Chromatin Loops and Methylated Histones Associated with Gene Activation"
advisor: Dr. Gerd Blobel
Collin Blakely (CAMB)
Dec 8, 3:00, Reunion Hall, John Morgan Building
"Developmental Events Influence Breast Cancer Risk: Insights from MYC, Stat5 and Pregnancy
advisor: Dr. Lewis Chodosh
Deepak Sampathu (Neuroscience)
Dec 15, 2:00, Reunion Hall, John Morgan Building
"Biochemical Studies of Pathological Inclusions in Alpha-Synucleinopathies and Frontotemporal Lobar Degeneration with Ubiquitin-Positive Inclusions"
advisor: Dr. Virginia M.Y. Lee
Chelsea Pinnix (CAMB)
Dec 16, 11:00, BRB auditorium
"Notch1 Activation Confers Transforming Properties to Primary Human Melanocytes and Promotes Human Melanoma Progression
advisor: Dr. Meenard Herlyn
Marcin Imielinski (GCB)
Dec 19, 10:00, 1311 Blockley Hall
"In silico analysis of microbial biosynthetic capabilities at the genome-scale"
advisor: Dr. Harvey Rubin
Carl Davis (CAMB)
Dec. 20, 3:00, 209 Johnson
"Interactions between West Nile virus and the C-type lectins DC-SIGN and DC-SIGNR"
advisor: Dr. Bob Doms
NOVEMBER
Marc Meulener (CAMB)
November 23, 2pm, 253 BRB
”Functional and Biochemical Characterization of Parkinsons Disease Gene DJ-1 in Drosophila”
advisor: Dr. Nancy Bonini
Jessica Dworet (CAMB)
November 2, 10am, 251 BRB
”The role of CREB in thyroid cell survival”
advisor: Dr. Judy Meinkoth
Michael Higley (Neuroscience)
Friday, October 28, 3:00pm, 140 John Morgan Building (Barchi library)
Neural Mechanisms of spatiotemporal sensory integration in the rat barrel system
advisor: Dr. Diego Contreras
Michael Silverman (Immunology)
Wednesday, October 26th, 1:00pm, Austrian Auditorium, CRB
”SLP-76: Complex regulation of FceRI signaling in mast cells”
advisor: Dr. Gary Koretzky
Farhad Abtahian (CAMB)
September 23, 3:30, class of '62 auditorium, John Morgan Bldg
"Regulation of blood and lymphatic vascular separation by Syk and SLP-76"
advisor: Dr. Gary Koretzky
Maria Chen (CAMB)
September 20, 10:00, 253 BRB II/III
"Compartmentalization and variation of envelope gp160 from various brain regions of SIVmac239-infected macaques"
advisor: Dr. Francisco Gonazalez Scarano
Ellen Krasik (Bioengineering)
September 16, 8:00am, Vagelos 5000
"Simulation of neutrophil adhesion under flow and the transition from rolling to firm adhesion"
advisor: Dr. Daniel Hammer
Bhaskar Srivastava (Immunology)
September 8, 2:00, BRB 252
"The development and maintenance of marginal zone B cells"
advisor: Dr. Dave Allman