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Recent Papers
Bevers MB, Neumar RW. Mechanistic role of calpains in postischemic neurodegeneration. J Cereb Blood Flow Metab. 2007; Epub ahead of print. [Abstract]
Siman R, Zhang C, Roberts VL, Pitts-Kiefer A, Neumar RW. Novel surrogate markers for acute brain damage: cerebrospinal fluid levels corrrelate with severity of ischemic neurodegeneration in the rat. J Cereb Blood Flow Metab. 2005; 25:1433-44. [Abstract]
Lawrence EJ, Dentcheva E, Curtis KR, Roberts VL, Siman R, Neumar RW. Neuroprotection with delayed initiation of prolonged hypothermia after in vitro transient global brain ischemia. Resuscitation, 2005; 64: 383-388. [Abstract]
Siman R, McIntosh TK, Soltesz KM, Chen Z, Neumar RW, Roberts VL. Proteins released from degenerating neurons are surrogate markers for acute brain damage. Neurobiol Dis. 2004; 16: 311-320. [Abstract]
Simpkins KL, Guttmann RP, Dong Y, Chen Z, Sokol S, Neumar RW, Lynch DR. Selective activation induced cleavage of the NR2B subunit by calpain. J Neurosci. 2003; 23: 11322-11331. [Abstract]
Neumar RW, Xu YA, Gada H, Guttmann RP, Siman R. Cross-talk between Calpain and Caspase Proteolytic Systems During Neuronal Apoptosis. J Biol Chem 2003; 278: 14162-14167. [Abstract]
Zhang C, Siman R, Xu YA, Mills AM, Frederick JR, Neumar RW. Related Articles, Links Comparison of calpain and caspase activities in the adult rat brain after transient forebrain ischemia. Neurobiol Dis 2002; 10: 289-05. [Abstract]
Neumar RW. Rule out TBI? Serum markers for traumatic brain injury. Ann Emerg Med. 2002; 39: 342-3. [Abstract]
Neumar RW, Meng FH, Mills AM, Xu YA, Zhang C, Welsh FA, Siman R. Calpain activity in the rat brain after transient forebrain ischemia. Exp Neurol 2001; 170: 27-35. [Abstract]
Neumar RW. Molecular mechanisms of ischemic neuronal injury. Ann Emerg Med 2000; 36: 483-506. [Abstract]
Siman R, Flood DG, Thinakaran G, Neumar RW. Endoplasmic Reticulum Stress-induced Cysteine Protease Activation in Cortical Neurons. Effect of an Alzheimer's Disease-Linked Presenilin-1 Knock-In-Mutation. J Biol Chem Year: 2001; 276: 44736-44743. [Abstract]
DeGracia DJ, Adamczyk S, Folbe AJ, Konkoly LL, Pittman JE, Neumar RW, Sullivan JM, Scheuner D, Kaufman RJ, White BC, Krause GS. Eukaryotic initiation factor 2alpha kinase and phosphatase activity during postischemic brain reperfusion. Exp Neurol 1999; 155: 221-227. [Abstract]
Neumar RW, DeGracia DJ, Konkoly LL, Khoury JI, White BC, Krause GS. Calpain mediates eukaryotic initiation factor 4G degradation during global brain ischemia J Cereb Blood Flow Metab 1998;18:876-881. [Abstract]