Neuroscience Graduate Group Bulletin Board



Open positions:

March 28, 2016

From Jorge Alvarez

A post-­‐doctoral position in neuroimmunology is available in the Alvarez lab. Our studies are focused to understand the biology of the CNS barriers during homeostasis and disease. We are currently studying how intrinsic CNS factors secreted at the neurovascular interface can modulate immune cell function in chronic neuroinflammatory disease like Multiple Sclerosis. In our studies we integrate in vitro, in vivo, ex-­‐vivo and in situ assays making use of human and animal systems. These efforts are strengthened by our interaction with local and external clinical centers, which aim to harmonize our scientific endeavors with the current understanding of human diseases.

We are seeking for a highly motivated applicant who have obtained or is in the process of obtaining a PhD or MD/PhD with a strong track record of scientific productivity. Experience in neuroimmunology is preferred but not required. Expertise in immunological techniques including flow cytometry, tissue culture, mouse models and molecular biology are sought. The candidate should also be able to work independently and have strong work ethic as well as good writing, verbal and interpersonal skills.

Review of applications will begin immediately.

Interested applicants should email a CV, cover letter describing career plans and contact information of 3 references to:

Jorge Iván Alvarez Assistant Professor Department of Pathobiology

School of Veterinary Medicine University of Pennsylvania

380 South University Avenue, 412 Hill Philadelphia, PA 19104-­‐4539



February 1, 2016

From Marc Schmidt:

Columbia Undergrad looking to work in Penn Neuroscience lab for the summer:


Sunny Chen is a freshman neuroscience major at Columbia University looking for a possible lab to work in this summer.

I have known Sunny for many years and find her to be a very hard worker, very bright and talented. She is also a delight to have around.

I would have taken her on in my lab but I already have 4 undergrads for the summer.

If you are interested, please contact her directly at:



November 9, 2015

Open Position for Research Assistant

The Lurie Family Foundations MEG Imaging Center at the Children’s Hospital of Philadelphia (Department of Radiology):

The brain imaging center at the Children’s Hospital of Philadelphia is seeking a Research Assistant. The selected research assistant will receive comprehensive training and scholarly experience to prepare the research assistant for competitive graduate or medical school programs.

Emphasis is on understanding the function and structure of the brain in typically developing children and in children with autism spectrum disorder. Techniques used include event-related potentials (ERPs) and event-related fields (ERFs), neuropsychological testing, magnetic resonance imaging (including diffusion tensor imaging), and functional magnetic resonance imaging. Applicants must have completed undergraduate work with a strong psychology and/or neuroscience/biology background. Experience with ERP/ERF or other neuroimaging methodologies is preferable. Experience programming and/or in statistics is also preferred. All applicants will be expected to have a GPA of at least 3.0 and must submit a written application describing their interest and future scientific goals. This position is available immediately.

The Children's Hospital of Philadelphia is an equal opportunity employer committed to creating a diverse, cooperative work environment. For further information contact Dr. Timothy P.L. Roberts:, (215) 426-0384. To apply, please send a CV, statement of research interests, and 3 letters of references to:

Timothy P.L. Roberts, Ph.D.
The Children's Hospital of Philadelphia
Division of Research
34th and Civic Center Blvd
2nd Floor Wood Building
Room 2115
Philadelphia, PA 19104




June 29, 2015

Open position for Postdoctoral Fellowship in Neurodegeneration

The Sattler laboratory is interested in studies of disease pathways for neurodegenerative disorders, including, but not exclusively, Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). Specifically, we aim to understand the role of the synaptic structures and synaptic proteins in disease progression and neurodegeneration, with an emphasis on the regulation and dysregulation of synaptic glutamate homeostasis and glutamate receptors. We approach these questions using several different complementary model systems, including human patient ‐ derived iPS cells, mouse models and human tissue. Our current main projects are aimed at understanding the role of synaptic dysfunction in C9orf72, and in addition to studying aberrant synaptic activity and morphology, we are particularly interested in studying the effects of RNA editing of the glutamate receptor subunit GluA2 due to the sequestration of the RNA editing protein ADAR to the C9orf72 repeat expansion. These mechanisms are being investigated using a multidisciplinary approach covering genetic, molecular, biochemical and sophisticated imaging techniques. Other projects involve the development of biomarker assays, including assays aimed at monitoring therapeutic interventions for C9orf72.

We welcome anybody who is talented, creative and highly motivated. A background in tissue culture, particularly iPS cell culture would be preferred, but is not required.The lab is well supported through a generous start up fund, NINDS grants as well as numerous disease foundation awards. Arizona is found in the southwestern region of the United States. It borders with New Mexico, Utah, Nevada, California, Mexico and even Colorado and offers a wide diversity of climates, including its desert as well as its mountain ranges and of course, large deep canyons, such as the Grand Canyon. No matter which outdoors activity you seek –you will find it here!

Please contact us by email ( or by phone (410 905 3812).


April 14, 2015

Dear Colleagues,

I seek your assistance in identifying outstanding candidates for twopost-doctoral positions in my laboratory at the US National Institutes of Health (NIH) that will become available on October 1, 2015. Candidates must have a Ph.D., M.D. orequivalent degree, and no more than five years of research experience since receipt of their doctoral degree. I am particularly interested in candidates with expertise in neurobiology, including experience working with neurons in primary culture or transgenic mouse models. Candidates with other types of expertise, including molecular biology, biochemistry, and fluorescence microscopy and imaging are also welcome to apply as long as they are exceptionally talented, motivated and willing to learn. My lab works on the molecular mechanisms of protein trafficking, with a more recent focus on the mechanisms of polarized sorting in neurons and the mechanisms of organelle positioning and motility. Below are references to some of our latest work. Information about post-doctoral training at the NIH can be found at this link:

Candidates should submit a message with an attached CV to

With best wishes,

JuanS. Bonifacino, Ph.D.
Head,Cell Biology and Metabolism Program (CBMP)
EuniceKennedy Shriver National Institute
ofChild Health and Human Development (NICHD)
NationalInstitutes of Health (NIH)
Building35, Room 2F-226
35AConvent Drive
Bethesda,MD 20892-3758

Recent publications

BORC, a MultisubunitComplex that Regulates Lysosome Positioning.
PuJ, Schindler C, Jia R, Jarnik M, Backlund P, Bonifacino JS
Dev Cell. 2015, in press

EARP is a multisubunit tetheringcomplex involved in endocytic recycling.
SchindlerC, Chen Y, Pu J, Guo X,Bonifacino JS.
Nat Cell Biol. 2015 Mar 23. doi:10.1038/ncb3129. [Epub ahead of print]

Adaptor proteins involved inpolarized sorting.
Bonifacino JS.
J Cell Biol. 2014 Jan 6;204(1):7-17.doi: 10.1083/jcb.201310021. Review.

The adaptor protein-1 μ1B subunitexpands the repertoire of basolateral sorting signal recognition in epithelialcells.
GuoX, Mattera R, Ren X, Chen Y, Retamal C, González A,Bonifacino JS.
Dev Cell. 2013 Nov 11;27(3):353-66.doi: 10.1016/j.devcel.2013.10.006.

Structural basis for recruitment andactivation of the AP-1 clathrin adaptor complex by Arf1.
RenX, Farías GG, Canagarajah BJ,BonifacinoJS, Hurley JH.
Cell. 2013 Feb 14;152(4):755-67.doi: 10.1016/j.cell.2012.12.042.

Signal-mediated,AP-1/clathrin-dependent sorting of transmembrane receptors to thesomatodendritic domain of hippocampal neurons.
FaríasGG, Cuitino L, Guo X, Ren X, Jarnik M, Mattera R,Bonifacino JS.
Neuron. 2012 Sep 6;75(5):810-23.doi: 10.1016/j.neuron.2012.07.007.

Our lab is located here:


April 7, 2015

Dear Colleagues,

A postdoctoral position is available in the lab of Dr. Michael Higley in the Department of Neurobiology
at the Yale School of Medicine in New Haven, CT. The lab uses a combination of 2-photon imaging,
optogenetics, and electrophysiology to understand how synaptic function contributes to circuit operations in the mouse neocortex. These experiments are conducted both in acute brain slices and in vivo. See recent publications (Chiu et al., Science 340:759; Higley, Nat. Rev. Neurosci. 15:567). Ongoing projects in the lab focus on elaborating the organization, function, and plasticity of GABAergic synapses. We are also investigating the roles of neuromodulators in regulating synaptic dynamics underlying visually-guided behavior. The goal of this new position is to explore how learning alters dendritic signaling and synaptic connectivity in the awake behaving mouse. Candidates must have completed a PhD prior to starting and should have at least one first-author paper accepted in a peer-reviewed journal. Experience with electrophysiology or microscopy is preferred. Start dates are flexible. Interested applicants should provide a cover letter with a brief statement of research experience, curriculum vitae, and names of three references to Dr. Michael Higley via email:

Warm regards,

Michael J. Higley, MD, PhD

Assistant Professor
Program in Cellular Neuroscience,
Neurodegeneration and Repair
PO Box 208001
New Haven, CT 06520-8001
T 203 785-4301
F 203 785-5263


March 31, 2015

University of California, San Diego
Postdoctoral Research Fellowship Opportunity

T32 in Geriatric Mental Health
(PI: Dilip V. Jeste, MD; co-Director: Cristian L. Achim, MD, PhD)

This research fellowship, funded by the National Institute of Mental Health, focuses on basic and applied research on older adults with mental disorders. The fellowship setting is a multidisciplinary research environment (e.g., psychology, psychiatry, neuroscience, pharmaceutical science) that is part of a larger research training program within UCSD’s Division of Geriatric Psychiatry. The T32 Fellowship is also affiliated with the Sam and Rose Stein Institute for Research on Aging, the John A. Hartford Center of Excellence in Geriatric Psychiatry, and the Clinical and Translational Science Award (CTSA) at UCSD.

Our fellowship prioritizes training for academic research careers.  Fellowships are for two years, with the possibility of a third year, and carry 12-month stipends in accordance with NIH rates. Applicants must be US citizens or permanent residents and have completed a doctoral degree in any relevant discipline. PhDs, MD/PhDs, and PharmDs with research experience are encouraged to apply.

We are looking for candidates with a solid background in basic neuroscience, including cellular and molecular mechanisms of brain aging, and preferably in vivo experimental models of aging, neuroinflammatory pathology and/or chronic neurodegenerative diseases; the focus will be on developing experimental paradigms leading to potential interventions promoting successful neurocognitive aging.

To apply, please submit a statement of research interests and CV to: Cristian L. Achim, MD, PhD

For more information, visit and


February 12, 2015

Army Research Laboratory – Postdoctoral Research Associate

Applications are invited to fill an open post-doctoral research position in the Structure-Function Cell of the Translational Neuroscience Branch of the Army Research Laboratory (Aberdeen Proving Ground, MD).

The ideal appointee will (1) have, or be in the final stages of obtaining, a PhD in psychology, cognitive science, neurology, neuroscience, bioengineering, or similar, and (2) have experience in human neuroimaging (particularly MRI). An interest in and general knowledge of structural and diffusion imaging data would be advantageous. Excellent computer programming skills and familiarity with neuroimaging software are essential. Candidates should be able to communicate effectively and flourish as the center of a diverse interdisciplinary research team.

Applications in the form of a covering letter, a CV with full publication list, and names of 3 references should be sent to Jean Vettel (

Location: Army Research Laboratory with flexibility to work collaboratively with the Complex Systems Group (Bassett) at Penn.

Starting Salary: Usually 72-75K per year, and commensurate with experience.

Start Date: Negotiable. Position open now.


January 22, 2015

Magali Saint-Geniez lab, Schepens Eye Research Institute- Postdoctoral Research Position

Research involves work in retinal degeneration. Applicants with cell culture and mouse experience are preferred.

Contact Jared Iacovelli at, for more information about the lab.