University of Pennsylvania School of Medicine
Department of Radiology
Center for Biomedical NMR
Contact:
Krzysztof P. Wroblewski, Ph.D.
Address: University of Pennsylvania School of Medicine
Room 96 John Morgan Building
Philadelphia, PA 19104-6055
e-mail: krzyszto@mail.med.upenn.edu
MISSION STATEMENT
The Center for Biomedical NMR was established to provide high-field small animal imaging and spectroscopy, multinuclear NMR spectroscopy, and NMR microscopy to the researchers of the University of Pennsylvania and the surrounding Philadelphia area. The Center provides unique non-invasive techniques to enhance the research potential of the scientists allowing to study metabolic processes in-vivo, expression of genes producing NMR detectable complexes, oxygen and ion transport, development of tumors, protein folding, macromolecular interaction and structure.
CAPABILITIES
· Design and perform virtually any high resolution NMR experiment in one, two, and three dimensions.
· Perform any biological NMR or MRI experiment on small animals (mice, hamsters, rats, rabbits).
· Perform any NMR experiment on perfused cells or organs.
· Obtain high resolution spectra of any nucleus from 107Ag to 3H including biologically important nuclei like 1H, 13C, 19F, 23Na, 31P.
· Process, analyze, and interpret 1D, 2D, and 3D data.
· Design and manufacture high resolution NMR probes, surface coils, and gradient coils.
· Program any desired pulse sequence for Bruker, Varian, and GE machines.
· Process any NMR and MRI data.
EQUIPMENT:
Bruker AMX-500
Bruker AMX-300/SWB
Bruker WM-360