University of Pennsylvania School of Medicine
Department of Radiology

Center for Biomedical NMR



Contact: Krzysztof P. Wroblewski, Ph.D.
Address: University of Pennsylvania School of Medicine
Room 96 John Morgan Building
Philadelphia, PA 19104-6055
e-mail: krzyszto@mail.med.upenn.edu


MISSION STATEMENT
The Center for Biomedical NMR was established to provide high-field small animal imaging and spectroscopy, multinuclear NMR spectroscopy, and NMR microscopy to the researchers of the University of Pennsylvania and the surrounding Philadelphia area. The Center provides unique non-invasive techniques to enhance the research potential of the scientists allowing to study metabolic processes in-vivo, expression of genes producing NMR detectable complexes, oxygen and ion transport, development of tumors, protein folding, macromolecular interaction and structure.

CAPABILITIES
Design and perform virtually any high resolution NMR experiment in one, two, and three dimensions.
Perform any biological NMR or MRI experiment on small animals (mice, hamsters, rats, rabbits).
Perform any NMR experiment on perfused cells or organs.
Obtain high resolution spectra of any nucleus from 107Ag to 3H including biologically important nuclei like 1H, 13C, 19F, 23Na, 31P.
Process, analyze, and interpret 1D, 2D, and 3D data.
Design and manufacture high resolution NMR probes, surface coils, and gradient coils.
Program any desired pulse sequence for Bruker, Varian, and GE machines.
Process any NMR and MRI data.

EQUIPMENT:
Bruker AMX-500
Bruker AMX-300/SWB
Bruker WM-360