Perelman School of Medicine at the University of Pennsylvania

McKay Orthopaedic Research Laboratory

Dodge Laboratory

Alexandra Farran

Alexandra Farran

Post-Doctoral Fellow
University of Pennsylvania

Hometown: Rouen, France

Education:Ph.D. Materials Science and Engineering, 2012, University of Delaware
M.S. Chemistry, 2005, National Graduate Chemistry School of Mulhouse (ENSCMu), France
B.S. Chemistry, 2003, National Graduate Chemistry School of Mulhouse (ENSCMu), France

Areas of Special Interest: During my Ph.D, my research was focused on developing hydrogels and bioreactors for vocal fold tissue engineering. Now my research is focused on studying the effect of growth factors and mechanical stimulations on chondrocytes for cartilage repair purposes. In my spare time I enjoy cooking, traveling, and spending time with my family.

Awards:
2011 Materials Science and Engineering Chairperson's Outstanding Graduate Student Award

Patents:
Jia, X.; Jia, M.; Jha, A. K.; Farran, A. J. E.; Tong, Z. "Dynamic Vibrational Method and Device for Vocal Fold Tissue Growth" Nonprovisional Patent Application, US 20100291045, May 15, 2010

Publications:
Teller, S. S.*; Farran, A. J. E.*; Xiao, L.; Jiao, T.; Duncan, R.L.; Clifton, R. J.; Jia, X. "High Frequency Viscoelastic Shear Properties of Vocal Fold Tissues: Implications for Vocal Fold Tissue Engineering", Tissue Engineering: Part A, 2012, DOI:10.1089/ten.TEA.2012.0023.

Grieshaber, S.E.*; Farran, A. J. E.*; Bai, S.; Kiick, K.L.; Jia, X. "Tuning the Properties of Elastin Mimetic Hybrid Copolymers via a Modular Polymerization Method", Biomacromolecules, 2012, 13(6), 1774-1786

Farran, A. J. E.; Teller, S. S.; Jia, F.; Clifton, R. J.; Duncan, R. L.; Jia, X. "Design and Characterization of a Dynamic Vibrational Culture System: Implications for Vocal Fold Tissue Engineering", Journal of Tissue Engineering and Regenerative Medicine, 2011, DOI: 10.1002/term.514

Farran, A. J. E.; Teller, S. S.; Jha, A. K.; Jiao, T.; Hule, R. A.; Clifton, R. J.; Pochan, D. P.; Duncan, R. L.; Jia, X. "Effects of Matrix Composition, Microstructure and Viscoelasticity on the Behaviors of Vocal Fold Fibroblasts Cultured in Three-Dimensional Hydrogel Networks", Tissue Engineering: Part A, 2010, 16(4), 1247-1261

Grieshaber, S. E.; Farran, A. J. E.; Lin-Gibson, S.; Kiick, K. L.; Jia, X. "Synthesis and Characterization of Elastin Mimetic Hybrid Polymers with Multiblock, Alternating Molecular Architecture and Elastomeric Properties", Macromolecules, 2009, 42(7), 2532-2541

Jiao, T.; Farran, A.; Jia, X.; Clifton, R. J. "High Frequency Measurements of Viscoelastic Properties of Hydrogels for Vocal Fold Regeneration", Experimental Mechanics, 2009, 49(2), 235-246

Korotkov, R. Y.; Ricou, P.; Farran, A. J. E. "Preferred orientation in polycrystalline SnO2 films grown by atmospheric pressure chemical vapor deposition", Thin Solid Films, 2006, 502(1-2), 79-87

Korotkov, R. Y.; Farran, A. J. E.; Culp, T.; Russo, D.; Roger, C. "Transport properties of undoped and NH3-doped polycrystalline SnO2 with low background electron concentrations", J. Appl. Phys., 2004, 96(11), 6445-6453

Conference Proceedings and Preprints:
Grieshaber, S. E.; Farran, A.; Kiick, K. L.; Jia, X. "Elastin Mimetic, Cell Adhesive Multiblock Copolymers", Polym. Prepr. 2010, 51, 88-89

Farran, A. J. E.; Jia, F.; Tong, Z.; Duncan, R. L.; Jia, X. "Towards in vitro Engineering of Vocal Fold Lamina Propria: Dynamic Culture", Polym. Mat. Sci. Eng. Prepr., 2009, 101, 1126-1127

Grieshaber, S. E.; Farran, A. J. E.; Kiick, K. L.; Jia, X. "Synthesis and Characterization of Hybrid Elastin Mimetic Multiblock Copolymers with Varying RGD Density", Polym. Mat. Sci. Eng. Prepr., 2009, 101, 1365-1366

Farran, A. J. E.; Duncan, R. L.; Jia, X. "Vocal Fold Tissue Engineering: 3D Culture of Vocal Fold Fibroblasts using Biomimetic Hydrogel Matrices", Polym. Mat. Sci. Eng. Prepr., 2008, 99, 844-845

Korotkov, R. Y.; Farran, A. J. E.; Culp, T.; Russo, D.; Roger, C. "Control of the preferred orientation in a polycrystalline SnO2 films grown by MOCVD", proceedings ICCG-5, 2004, 221

Book Chapters:
Farran, A. J. E.; Tong, Z.; Witt, R.L.; Jia, X. "Tissue Engineering Strategies for Vocal Fold Repair and Regeneration" In "Engineering Biomaterials for Regenerative Medicine" Bhatia, S. K. Ed., New York, NY, Springer, 253-284, 2012

Grieshaber, S. E.; Jha, A. K.; Farran, A. J. E.; Jia, X. "Hydrogels in Tissue Engineering" in "Biomaterials for Tissue Engineering: A Review of the Past and Future Trends" Burdick, J. A.; Mauck, R. L. Eds., New York, NY, Springer, 9-46, 2011

Abstracts:
Farran, A. J. E.*; Jha, A. K.; Duncan, R. L.; Jia, X. "Engineering Biomimetic Microenvironments for the Functional Regeneration of Vocal Fold Lamina Propria", Podium presentation, Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX, USA, November 2010

Farran, A. J. E.*; Duncan, R. L.; Jia, X. "Engineering Biomimetic Microenvironments for the Functional Regeneration of Vocal Fold Lamina Propria", Podium presentation, 3rd Annual Materials Research Society (MRS) Symposium, Newark, DE, USA, October 2010

Grieshaber, S. E.; Farran, A. J. E.*; Kiick, K. L.; Jia, X. "Elastin Mimetic Hybrid Polymers as Conducive Scaffolds for Tissue Engineering", Poster Presentation, Biomedical Engineering Society (BMES) Annual Fall Meeting, Austin, TX, October 2010

Grieshaber, S. E.*; Farran, A. J. E.; Kiick, K. L.; Jia, X. "Elastin mimetic, cell adhesive multiblock hybrid copolymers", Podium presentation, POLY, 240th American Chemical Society (ACS) National Fall Meeting, Boston, MA, USA, August 2010

Grieshaber, S. E.; Farran, A. J. E.; Kiick, K. L.; Jia, X.* "Elastin Mimetic Hybrid Polymers for Vocal Fold Tissue Engineering", Poster Presentation, Society for Biomaterials (SFB) Annual Meeting, Seattle, WA, April 2010

Farran, A. J. E.*; Tong, Z.; Jia, F.; Duncan, R. L.; Jia, X. "Tissue Engineering of Vocal Fold Lamina Propria", Podium presentation, 2nd Annual Materials Research Society (MRS) Symposium, Newark, DE, USA, October 2009

Farran, A. J. E.*; Jia, F.; Tong, Z.; Duncan, R. L.; Jia, X. "Towards in vitro Engineering of Vocal Fold Lamina Propria: Dynamic Culture", Podium presentation, Biomedical Engineering Society (BMES) Annual Meeting, Pittsburg, PA, USA, October 2009

Farran, A. J. E.*; Jia, F.; Tong, Z.; Duncan, R. L.; Jia, X. "Towards in vitro Engineering of Vocal Fold Lamina Propria: Dynamic Culture", Podium presentation, PMSE, 238th American Chemical Society (ACS) National Fall Meeting, Washington D.C., USA, August 2009

Grieshaber, S. E.*; Farran, A. J. E.; Kiick, K. L.; Jia, X. "Synthesis and Characterization of hybrid elastin mimetic multiblock copolymers with varying RGD density", Podium presentation, PMSE, 238th American Chemical Society (ACS) National Fall Meeting, Washington D.C., USA, August 2009

Farran, A. J. E.*; Jia, F.; Tong, Z.; Duncan, R. L.; Jia, X. "Tissue Engineering of Vocal Fold Lamina Propria", Poster presentation, 2nd annual Mid-Atlantic Frontiers at the Chemistry and Biology Interface (CBI) symposium, Baltimore, MD, USA, May 2009

Farran, A. J. E.*; Jia, F.; Tong, Z.; Duncan, R. L.; Jia, X. "Tissue Engineering of Vocal Fold Lamina Propria", Poster presentation, Center for Biomedical Engineering Research: Biomechanics Research Symposium, Newark, DE, USA, May 2009

Grieshaber, S. E.; Farran, A. J. E.; Lin-Gibson, S.; Kiick, K. L.; Jia, X.* "Synthesis and Characterization of Elastin Mimetic Hybrid Polymers with Alternating Molecular Architecture and Elastomeric Properties", Poster Presentation, Gordon Research Conferences (GRC): Macromolecular Materials, Ventura, CA, January, 2009

Farran, A. J. E.*; Jia, F.; Jha, A. K.; Duncan, R. L.; Jia, X. "Biomimetic Approaches for Vocal Fold Tissue Engineering", Podium presentation, Materials Research Society (MRS) Annual Fall Meeting, Boston, MA,USA, December 2008

Farran, A. J. E.*; Jia, F.; Jha, A. K.; Duncan, R. L.; Jia, X. "Biomimetic Approaches for Vocal Fold Tissue Engineering", Podium presentation, Biomedical Engineering Society (BMES) Annual Meeting, Saint-Louis, MO, USA, October 2008

Jia, F.; Farran, A. J. E.*; Duncan, R. L.; Jia, X. "High Frequency Vibrational Stimulation of Vocal Fold Fibroblasts", Poster presentation, Biomedical Engineering Society (BMES) Annual Meeting, Saint-Louis, MO, USA, October 2008

Jha, A. J.; Grieshaber, S. E.; Farran, A. J. E.; Jia, F.; Woods, M.; Jia, X.* "Synthetic Extracellular Matrices with Controlled Architectures and Improved Mechanical Properties for Tissue Engineering", Poster Presentation, Biomedical Engineering Society (BMES) Annual Meeting, St. Louis, MO, USA, October, 2008

Farran, A. J. E.*; Duncan, R. L.; Jia, X. "Vocal Fold Tissue Engineering: 3-D Culture of Vocal Fold Fibroblasts using Biomimetic Hydrogel Matrices", Podium presentation, PMSE, 236th American Chemical Society (ACS) National Fall Meeting, Philadelphia, PA, USA, August 2008

Jha, A. J.; Grieshaber, S. E.; Farran, A. J. E.; Jia, F.; Woods, M.; Jia, X.* "Tissue Engineering of Vocal Fold Lamina Propria", Poster Presentation, GRC: Signal Transduction By Engineered Extracellular Matrices, Lewiston, MI, July 11-16, 2008