Perelman School of Medicine at the University of Pennsylvania

McKay Orthopaedic Research Laboratory

Dyment Laboratory

Welcome to Dyment Laboratory

The primary goals of our research program are directed towards understanding the genetic, cellular, and mechanical mechanisms that regulate normal development, disease, and repair of tissues in the joint. Our lab focuses on 1) identifying the resident progenitor populations that contribute to normal growth, healing, and repair, 2) characterizing the mechanisms that control the expansion and differentiation of these cells, and 3) ascertaining the phenotypical markers that define the stages of differentiation from early stem/progenitors to mature cell types. These goals in combination will guide future therapeutic strategies and provide success criteria to assess efficacy moving forward. For more information, please see our Ongoing Research Projects page.