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| January 16, 2012 | Hsiao EC, Millard SM, Louie A, Huang Y, Conklin BR, Nissenson RA. Ligand-Mediated Activation of an Engineered Gs G Protein-Coupled Receptor in Osteoblasts Increases Trabecular Bone Formation. |
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| November 14, 2011 | Li G, Zheng B, Meszaros LB, Vella JB, Usas A, Matsumoto T, Huard J. Identification and characterization of chondrogenic progenitor cells in the fascia of postnatal skeletal muscle. |
| October 10, 2011 | Zaiss MM, Axmann R, Zwerina J, Polzer K, Guckel E, Skapenko A, Schulze-Koops H, Horwood N, Cope A, Schett G. Treg cells suppress osteoclast formation: a new link between the immune system and bone. |
| September 12, 2011 | Liu Y, Wang L, Fatahi R, Kronenberg M, Kalajzic I, Rowe D, Li Y, Maye P. Isolation of murine bone marrow derived mesenchymal stem cells using Twist2 Cre transgenic mice. |
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| January 26, 2006 | David Glaser, Toshiyuki Matsuoka, Per E. Ahlberg, Nicoletta Kessaris, Palma Iannarelli, Ulla Dennehy, William D. Richardson, Andrew P. McMahon and Georgy Koentges. Neural crest origins of the neck and shoulder. Nature 436: 347-355, 2005. |
| December 19, 2005 | Jennifer Fiori, Stephen E. Kendall, Chiara Battelli, Sarah Irwin, Jane G. Mitchell, Carlotta A. Glackin, and Joseph M. Verdi. NRAGE mediates p38 activation and neural progenitor apoptosis via the bone morphogenetic protein signaling cascade. Molecular and Cellular Biology 25(17): 7711-7724, 2005. |
| November 3, 2005 | Paul Billings, Didier Montarras, Jennifer Morgan, Charlotte Collins, Frederic Relaix, Stephane Zaffran, Ana Cumano, Terence Partridge, Margaret Buckingham. Direct isolation of satellite cells for skeletal muscle regeneration. Science 309: 2064-2067, 2005. |
| October 24, 2005 | George Feldman, Laurie A. Boyer, et al (2005). Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122: 1-10. |
| August 11, 2005 | Berangere Saucy, A. Afshan Ali, Robert S. Weinstein, Scott A. Stewart, A. Michael Parfitt, Stavros C. Manolagas, and Robert L. Jilka. Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation. Endocrinology 146(3): 1226-1235, 2005. |
| April 28, 2005 | Paul Billings, Trina K. Jeffery, Paul D. Upton, Richard C. Trembath and Nicholas W. Morrell. BMP4 inhibits proliferation and promotes myocyte differentiation of lung fibroblasts via Smad1 and JNK pathways. Am J Physiol Lung Cell Mol Physiol 288:L370-L378, 2005. |
| February 22, 2005 | Reem Kanaan, Jie Liu, Julie G. Nealon and Lee S. Weinstein (2005). Distinct patterns of abnormal GNAS imprinting in familial and sporadic pseudohypoparathyroidism type 1B. Human Molecular Genetics 14 (1): 95-102. |
| January 25, 2005 | George Feldman, Ritsert C. Jansen and Jan-Peter Nap (2004). Regulating gene expression: surprises still in store. Trends Genet 20(5):223-225. Gael Yvert, et al (2003). Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors. Nature Genetics 35(1): 57-64. |
| December 14, 2004 |
Gisela Melcon, M.D.,
Research Associate: Jan Hellemans et al
(2004). Loss-of-function mutations in LEMD3 result in osteopoikilosis,
Buschke-Ollendorff syndrome and melorheostosis. Nature Genetics
36(11): 1213-1218. |
| November
16, 2004 |
Jennifer Fiori, Graduate
Student:Hui-Kuan Lin, Stephan
Bergmann & Pier Paolo Pandolfi (2004). Cytoplasmic PML function
in TGF-Beta signalling. Nature 431:205-211. Christine LeRoy
and Jeffrey L. Wrana (2004). An unexpected social servant
Nature 431:142. |
| October
26, 2004 |
Paul Billings, Ph.D.,
Research Associate:Lixin Kan, Min Hu,
William A. Gomes, and John A. Kessler Transgenic Mice Overexpressing
BMP4 Develop a Fibrodysplasia Ossificans Progressiva (FOP)-Like
Phenotype. American Journal of Pathology 165: 1107-1115,
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| July
28, 2004 |
Reem Kanaan, PhD, Research
Associate:Piero Crespo, Teresa
G. Cachero, Ningzhi Xu, and J. Silvio Gutkind. Dual Effect
of Adrenergic Receptors on Mitogen-activated Protein Kinase.
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| June
23, 2004 |
George Feldman, D.M.D.,
Ph.D., Research Associate: Peter Bialek, et al.
A Twist Code Determines the Onset of Osteoblast Differentiation.
Developmental Cell 6: 423-435, 2004. |
| May
27, 2004 |
Brett Gibson, M.D.,
Orthopaedic Resident:Joanna L. Ford, Derek
E. Robinson, Brigitte E. Scammell. (2004) Endochondral ossification
in fracture callus during long bone repair: the localisation
of 'cavity-lining cells' within the cartilage. Journal of
Orthopaedic Research 22, 368-375. |
| April
28, 2004 |
XiangYang Jaio, M.D.,
Research Associate: William F. Pendergraft,
Gloria A. Preston, Ruchir R. Shah, Alexander Tropsha, Charles
W. Carter, J. Charles Jennette, Ronald J. Falk. Autoimmunity
is triggered by cPR-3 (105-201), a protein complementary
to human autoantigen proteinase-3. Nature Medicine 10(1):72-79,
2004. |
| March
24, 2004 |
Paul Billings, Ph.D.,
Research Associate:Seto, H., Kamekura,
S., Miura, T., Yamamoto, A. Chikuda, H., Ogata, T., Hiraoka,
H., Oda, H., Nakamura, K., Kurosawa, H., Chug, U.I., Kawaguchi,
H. and Tanaka, S. Distinct roles of Smad pathways and p38
pathways in cartilage-specific gene expression in synovial
fibroblasts. Journal of Clinical Investigation 113: 718-726,
2004 Byfield, S.D. and Roberts,
A.B. Lateral signaling enhances TGF-b response complexity.
Trends in Cell Biology 14: 107-111, 2004 |
| February
18, 2004 |
Reem Kanaan, Ph.D.,
Research Associate: Spinella-Jaegle, S.
Roman-Roman, C. Faucheu, F.-W. Dunn, S. Kawai, S. Gallea,
V. Stiot, A.M. Blanchet, B. Courtois, R. Baron, and G. Rawadi.
Opposite effects of bone morphogenetic protein-2 and transforming
growth factor-1 on osteoblast differentiation. Bone 29(4):323-330,
2001. |
| January
28, 2004 |
Paul Billings, Ph.D.,
Research Associate:Rajiv D. Machado, Nung
Rudarakanchana, Carl Atkinson, Julia A. Flanagan, Rachel
Harrison, Nicholas W. Morrell and Richard C. Trembath. Functional
interaction between BMPR-II and Tctex-1, a light chain of
Dynein, is isoform-specific and disrupted by mutations underlying
primary pulmonary hypertension. Human Molecular Genetics,
Vol. 12(24): 3277-3286, 2003.Marcos Gonzalez-Gaitan
and Harald Stenmark. Endocytosis and Signaling: A Relationship
under Development. Cell, 115:513-521, November 26, 2003.
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December 23, 2003 |
George Feldman, D.M.D.,
Ph.D. Research Associate:Frank B. Dean, Seiyu
Hosono, Linhua Fang, Xiaohong Wu, A. Fawad Faruqi, Patricia
Bray-Ward, Zhenyu Sun, Qiuling Zong, Yuefen Du, Jing Du,
Mark Driscoll, Wanmin Song, Stephen F. Kingsmore, Michael
Egholm, and Roger S. Lasken. Comprehensive human genome
amplification using multiple displacement amplification.
PNAS 99(8): 5261-5266, April 16, 2002. |
| Novermber
19, 2003 |
Brett Gibson, M.D.,
Orthopaedic Resident:TBA |
| October
29, 2003 |
Jennifer Fiori, Graduate
Student:Shepherd T. and Nachtigal,
M. Identification of a Putative Autocrine Bone Morphogenetic
Protein Signaling Pathway in Human Ovarian Surface Epithelium
and Ovarian Cancer Cells. Endocrinology 2003; 144(8):3306-3314.
Fu, Y., O'Connor, L.,
Shepherd, T., Nachtigal, M. The p38 Inhibitor, PD169316,
Inhibits Transforming Growth Factor Beta Induced Smad Signaling
in Human Ovarian Cancer Cells. Biochemical and Biophysical
Research Communications 2003; 310:391-397. |
| August
27, 2003 |
Chuanzhao Li, Ph.D.,
Research Associate: Haleem J. Issaq, Timothy
D. Veenstra, Thomas P. Conrads, and Donna Felschow. The
SELDI-TOF MS Approach to Proteomics: Protein Profiling and
Biomarker Identification. Biochemical and Biophysical Research
Communications 2002; 292: 587-592. Lisa H. Cazares, Bao-Ling
Adam, Michael D. Ward, Suhail Nasim, Paul F. Schellhammer,
O. John Semmes and George L. Wright, Jr. Normal, Benign,
Preneoplastic, and Malignant Prostate Cells Have Distinct
Protein Expression Profiles Resolved by Surface Enhanced
Laser Desorption/Ionization Mass Spectrometry. Clinical
Cancer Research 2002; 8: 2541-2552. |
| July
30, 2003 |
XiangYang Jaio, M.D.,
Research Associate: Warren, S.M., Burnet,
L.J., Harland, R.M., Economides, A.N., Longaker, M.T. The
BMP antagonist noggin regulates cranial suture fusion. Nature
2003; 422:625-629. |
| May
28, 2003 |
George Feldman, D.M.D.,
Ph.D., Research Associate: Y.Kanzaki, F. Onoue,
H. Sakurai, and T. Ide (2003). Telomerase upregulates expression
levels of interleukin (IL)-1 alpha, IL-1 beta, IL-6, IL-8
and granulocyte-macrophage colony-stimulating factor in
normal human fibroblasts. BBRC 305: 150-154.C. Lindvall, M. Hou,
T. Komurasaki, C. Zheng, M. Henriksson, J. Sedivy, M. Bjorkholm,
B.T. Teh, M. Nordenskjold, and D. Xu (2003). Molecular Characterization
of Human Telomerase Reverse Transcriptase-immortalized Human
Fibroblasts by Gene Expression Profiling: Activation of
the Epiregulin Gene1,2. Cancer Research 63, 1743-1747.D.Aisner, W. Wright,
and J. Shay (2002). Telomerase regulation: not just flipping
the switch. Oncogenes and cell proliferation, 80-85. |
| February
11 , 2003 |
Jen Fiori, Graduate
Student: G. Praveen Raju, Neviana
Dimova, Peter S. Klein, and Hui-Chuan Huang (2003). SANE,
a Novel LEM Domain Protein, Regulates Bone Morphogenetic
Protein Signaling through Interaction with Smad1. Journal
of Biological Chemistry 278(1): 428-437. |
| January
28, 2003 |
Paul Billings, Ph.D.
Research Associate:TBA |
| December
17, 2002 |
Shelby Blythe, Graduate
Student:Shu Takeda, Florent
Elefteriou, Regis Levasseur, Xiuyun Liu, Liping Zhao, Keith
L. Parker, Dawna Armstrong, Patricia Ducy and Gerard Karsenty
(2002). Leptin regulates bone formation via the sympathetic
nervous system. Cell 111, 305-317. |
| November
26, 2002 |
Bob Pignolo, M.D.,
Ph.D. Research Fellow:Transdifferentiation
Into Osteoblasts: Jeremy Skillington, Lisa Choy and Rik
Derynck (2002). Bone morphogenetic protein and retinoic
acid signaling cooperate to induce osteoblast differentiation
of preadipocytes. The Journal of Cell Biology 159 (1):135-146. |
| October
15 , 2002 |
George Feldman, D.M.D.,
Ph.D. Research Associate: Gerald R. Crabtree
and Eric N. Olson (2002). NFAT Signaling: Choreographing
the Social Lives of Cells. Cell 109:S67-S79.Ann M. Ranger, Louis
C. Gerstenfeld, Jinxi Wang, Tamiyo Kon, Hyunsu Bae, Ellen
M. Gravallese, Melvin J. Glimcher, and Laurie H. Glimcher
(2000). The Nuclear Factor of Activated T Cells (NFAT) Transcription
Factor NFATp (NFATc2) Is a Repressor of Chondrogenesis.
J. Exp. Med 191:9-21.Masuhiro Tomita, Martina
I. Reinhold, Jeffery D. Molkentin, Michael C. Naski (2002).
Calcineurin and NFAT4 Induce Chondrogenesis. JBC Papers
in Press. Published on September 17, 2002. |
| July
30, 2002 |
Deyu Zhang, Research
Associate:X. Han and S. Amar
(2002). Identification of Genes Differentially Expressed
in Cultured Human Periodontal Ligament Fibroblasts vs. Human
Gingival Fibroblasts by DNA Microarray Analysis. J Dent
Res 81(6):399-405. |
| July
2, 2002 |
Chuanzhao Li, Ph.D.,
Research Associate:Nakashima K., Zhou
X., Kunkel G., Zhang Z., Deng JM., Behringer RR., and de
Crombrugghe B (2002). The novel zinc finger-containing transcription
factor osterix is required for osteoblast differentiation
and bone formation. Cell. 108(1):17-29, 2002 Jan 11. |
| June
4, 2002 |
Yangguan Wu, M.D.,
Research Associate:Kenneth W. Liechty,
Tippi C. MacKenzie, Aimen F. Shaaban, Antoneta Radu, AnneMarie
B. Moseley, Robert Deans, Daniel R. Marshak and Alan W.
Flake (2000). Human mesenchymal stem cells engraft and demonstrate
site-specific differentiation after in utero transplantation
in sheep. Nature Medicine 6(11):1282-1286.William M. Rideout
III, Konrad Hochedlinger, Michael Kyba, George Q Daley,
and Rudolf Jaenisch (2002). Correction of a genetic defect
by nuclear transplantation and combined cell and gene therapy.
Cell 109: 17-27. |
| April
23, 2002 |
Lourdes Serrano de
la Pena, Ph.D. Post Doc:Anja Nohe, Sylke Hassel,
Marcelo Ehrlich, Florian Neubauer, Walter Sebald, Yoav I.
Henis, and Petra Knaus (2002). The Mode of Bone Morphogenetic
Protein (BMP) Receptor Oligomerization Determines Different
BMP-2 Signaling Pathways. Journal of Biological Chemistry,
277(7): 5330-5338. |
| March
26, 2002 |
George Feldman, D.M.D.,
Ph.D., Research Associate:Trey Ideker, Vesteinn
Thorsson, Jeffrey A. Ranish, Rowan Christman, Jeremy Buhler,
Jimmy K. Eng, Roger Bumgarner, David R. Goodlett, Ruedi
Aebersold, Leroy Hood (2001). Integrated Genomic and Proteomic
Analyses of a Systematically Perturbed Metabolic Network.
Science, Vol. 292:929-933. |
| March
5, 2002 |
Paul Billings, Ph.D.,
Research Associate:Askew GR, Doetschman
T and Lingrel JB (1993). Site-directed point mutations in
embryonic stem cells: a gene-targeting tag-and-exchange
strategy Mol Cell Biol 13, 4115-4124. Stem cells: A primer.
National Institutes of Health May 2000. |
