Perelman School of Medicine at the University of Pennsylvania

McKay Orthopaedic Research Laboratory

Liu Laboratory

Allison Altman, Ph.D.

Allison

Postdoc Research Scientist
University of Pennsylvania

HOMETOWN
Wilmington, DE

EDUCATION
Ph.D. Biomechanics & Movement Science, 2012, University of Delaware, Newark, DE
M.S. Biomechanics & Movement Science, 2009, University of Delaware, Newark, DE
B.S. Biomedical Engineering, 2007, University of Rochester, Rochester, NY

AREA OF EXPERTISE
Biomechanics of Running Injuries
Motion Analysis
Musculoskeletal Modeling
MicroCT Imaging and Analysis
In vivo MicroCT Imaging

HONERS & AWARDS

  1. Travel Fund Award, UPenn Biomedical Postdoctoral Program
  2. New Investigator Recognition Award (NIRA) Finalist, Orthopaedic Research Society
  3. President's Poster Competition Award, American Society of Bone and Mineral Research
  4. Endocrine Fellow, Endocrine Fellows Foundation
  5. Young Investigator Award, AAOS/ORS Bone Quality and Fracture Prevention Research Symposium, 2013
  6. Force & Motion Travel Scholarship, Advanced Mechanical Technology Inc., 2011
  7. ASB Grant-In-Aid, American Society of Biomechanics, 2011
  8. Alumni Enrichment Award, University of Delaware Alumni Office, 2011
  9. ACSM Student Travel Award, Biomechanics Interest Group of the American College of Sports Medicine, 2010
  10. Professional Development Award, University of Delaware Graduate Office, 2008 & 2009

MANUSCRIPTS

  1. Altman, AR, de Bakker, CMJ, Tseng, WJ, Chandra, A, Qin, L, Liu, XSL. Enhanced individual trabecular repair and its mechanical implications in PTH and Alendronate treated rat tibial bone. Journal of Biomechanical Engineering. Sep 2014
  2. Altman AR, Tseng WJ, de Bakker CMJ, Huh BK, Chandra A, Qin L, Liu XS. A closer look at the immediate trabeculae response to combined parathyroid hormone and alendronate treatment. Bone. 2014; 61: 149-157
  3. Lan L, Luo S, Huh BK, Chandra A, Altman AR, Qin L, Liu XS. 3D Image Registration is Critical to Ensure Accurate Detection of Longitudinal Changes in Trabecular Bone Density, Microstructure, and Stiffness Measurements in Rat Tibiae by In Vivo Micro Computed Tomography. Bone. 2013; 56(1):83-90  
  4. Chandra A, Lan S, Zhu J, Siclari V, Altman AR, Cengel K, Liu XS, Qin L. PTH Prevents the Adverse Effects of Focal Radiation on Bone Architecture in Young Rats. Bone. 2013; 55(2):449-457 
  5. Altman AR, Davis IS. Barefoot Running: Biomechanics and Implications for Running Injuries. Current Sports Medicine Reports. 2012; Sept/Oct 11(5):244-250 Invited publication 
  6. Altman AR, Reisman DS, Higginson JS, Davis IS. A kinematic comparison of split-belt and single-belt treadmill walking and the effects of accommodation. Gait & Posture. 2012; 35:287-291
  7. Altman AR, Davis IS. A kinematic method for footstrike pattern detection in barefoot and shod runners. Gait & Posture. 2012; 35:298-300
  8. Miller TL, Zhu Y, Altman AR, Dysart K, Shaffer TH. Sequential alterations in tracheal mechanical properties in the neonatal lamb: Effects of mechanical ventilation. Pediatr Pulmonol. 2007; 42(2):141-14
  9. Miller TL, Altman AR, Tsuda T, & Shaffer TH. A novel ultrasound imaging method and preparation for the in vivo evaluation of tracheal kinetics and mechanics. J Biomech. 2007; 40(7):1615-1621

ABSTRACTS

  1. Altman AR, Lott, C, Tseng, WJ, de Bakker, CMJ, Liou, SD, Lin, T, Qin L, Liu XS. Intermittent PTH after prolonged bisphosphonate treatment improves bone structure by inducing substantial new bone formation with decoupled, inhibited bone resorption in ovariectomized rats. Orthopaedic Research Society, Las Vegas, 2015
  2. de Bakker, CMJ, Altman AR, Li, C, Tseng, WJ, Liu XS. A novel image transformation scheme minimizes interpolation artifacts and allows reproducible measurement of trabecular bone remodeling through ╬╝CT-based in vivo dynamic histomorphometry. Orthopaedic Research Society, Las Vegas, 2015
  3. Altman AR, Lott C, Tseng WJ, de Bakker, CMJ, Liou SD, Lin T, Qin L, Liu XS. Intermittent PTH after prolonged bisphosphonate treatment improves trabecular bone microarchitecture and alleviates bone tissue hypermineralization by inducing substantial new bone formation. American Society of Bone and Mineral Research, Houston, TX, 2014
  4. Altman AR, Tseng WJ, Chandra A, Qin L, Liu XS. Intermittent parathyroid hormone treatment enhances both trabecular and cortical bone modeling in growing rats. American Society of Bone and Mineral Research, Houston, TX, 2014
  5. de Bakker, CMJ, Altman AR, Li C, Tseng WJ, Liu XS. Pregnancy and lactation bone loss cause long-lasting structural deterioration of the maternal skeleton that accumulates over multiple reproductive cycles. American Society of Bone and Mineral Research, Houston, TX, 2014
  6. Altman AR, Jeong Y, Chandra A, Kosel E, Qin L, Kim DG, Liu XS. Intermittent parathyroid hormone treatment alleviates abnormalities in bone tissue mineralization and material properties associated with bisphosphonate treatments. Poster Presentation. Orthopaedic Research Society Annual Meeting, New Orleans, LA, March 15-18, 2014.
  7. Altman AR, de Bakker CMJ, Chandra A, Huh BK, Qin L, Liu XS. Enhanced individual trabecular repair and its mechanical implications in PTH and alendronate treated rat tibial bone. NIRA Finalist, Poster & Podium Presentation. Orthopaedic Research Society Annual Meeting, New Orleans, LA, March 15-18, 2014.
  8. Li C, Lott C, Altman AR, de Bakker CMJ, Liu XS. Comparison between ovariectomy and lactation induced bone loss: a dynamic imaging study. Poster Presentation. Orthopaedic Research Society Annual Meeting, New Orleans, LA, March 15-18, 2014.
  9. de Bakker CMJ, Altman AR, Li C, Tseng W-J, Tribble MB, Huh BK, Chandra A, Qin L, Liu XS. Alendronate and PTH combination therapy stimulates bone formation while inhibiting bone resorption activities in the rat tibia: a longitudinal, in vivo, dynamic bone histomorphometry study. Poster Presentation. Orthopaedic Research Society Annual Meeting, New Orleans, LA, March 15-18, 2014.
  10. de Bakker CMJ, Altman AR, Li C, Liu XS. Pregnancy, lactation and weaning induce substantial changes in bone microarchitecture and remodeling in rat tibiae. Poster Presentation. Orthopaedic Research Society Annual Meeting, New Orleans, LA, March 15-18, 2014.
  11. Altman AR, Breitton K, Zhao G, Parajuli A, Tseng W-J, Wang L, Wang JHC, Liu XS. Intensive treadmill running induces bone microstructural deterioration in mouse femoral bone. Poster Presentation. Orthopaedic Research Society Annual Meeting, New Orleans, LA, March 15-18, 2014.
  12. Altman AR, Huh BK, Tseng W-J, Chandra A, Qin L, Liu XS. A Closer Look at the Immediate Trabeculae Response to Combined Parathyroid Hormone (PTH) and Alendronate (ALN) Treatment. Poster Presentation. American Society for Bone and Mineral Research Annual Meeting, Baltimore, MD, 2013.
  13. Altman AR, Breitton K, Zhao G, Huh BK, Tseng W-J, Wang JHC, Liu XS. Intensive treadmill running induces microstructural deterioration in mouse femoral trabecular bone. Poster Presentation. American Society for Bone and Mineral Research Annual Meeting, Baltimore, MD, 2013.
  14. de Bakker CMJ, Altman AR, Tseng W-J, Tribble MB, Huh BK, Chandra A, Qin L, Liu XS. In Vivo Bone Dynamic Imaging Reveals Increased Bone Formation and Inhibited Bone Resorption in Rat Tibia in Response to Combined Alendronate (ALN) and PTH Treatment. American Society for Bone and Mineral Research Annual Meeting, Baltimore, MD, 2013.
  15. Altman AR, Huh BK, Chandra A, Tseng W-J, Qin L, Liu XS. 3D in vivo dynamic imaging of PTH's anabolic action. Podium Presentation. American Society of Mechanical Engineers Summer Bioengineering Conference, Sunriver, OR, 2013
  16. Altman AR, Huh BK, Luo S, Chandra A, Qin L, Liu XS. A closer look at the immediate trabecular response to combined parathyroid hormone and alendronate treatment. Podium Presentation. Orthopaedic Research Society, San Antonio, TX, 2013
  17. Huh BK, Luo S, Altman AR, Chandra A, Lan S, Qin L, Liu XS. Age-dependent responses in 3D architectural developmental patterns in the rat tibia to daily parathyroid hormone administration. Poster Presentation. Orthopaedic Research Society, San Antonio, TX, 2013
  18. Luo S, Lan S, Chandra A, Huh BK, Altman AR, Qin L, Liu XS. 3D image registration is critical to ensure accurate detection of longitudinal changes in bone microstructure and mineral density measurements in rats by in vivo micro computed tomography. Poster Presentation. Orthopaedic Research Society, San Antonio, TX, 2013
  19. Altman AR, Davis IS. Comparison of tibial strains and strain rates in barefoot and shod running. Podium Presentation. American Society of Biomechanics, Gainsville, FL, 2012
  20. Altman AR, Davis IS. Running-related injuries during the transition from shod to barefoot running. Thematic Poster Presentation. American College of Sports Medicine, San Francisco, CA, 2011
  21. Altman AR, Davis IS. Do barefoot runners display more variability in footstrike mechanics than shod runners? American Society of Biomechanics, Long Beach, CA, 2011
  22. Altman AR, Davis IS. Comparing barefoot running to an altered strike pattern in shoes. Thematic Poster Presentation. American College of Sports Medicine, Denver, CO, 2011
  23. Altman AR, Davis IS. A kinematic method for footstrike pattern detection. Poster Presentation. American Society of Biomechanics, Providence, RI, 2010
  24. Altman AR, Davis IS. Impact loading can be reduced with a midfoot strike pattern. Poster Presentation. American College of Sports Medicine, Baltimore, MD, 2010
  25. Altman AR, Davis IS. Is midfoot striking during running advantageous over rearfoot or forefoot striking? Poster Presentation. American Society of Biomechanics, State College, PA, 2009
  26. Altman AR, Davis IS. Muscle onset timing in subjects trained to reduce tibial shock. Poster Presentation. American College of Sports Medicine, Seattle, WA, 2009
  27. Altman AR, Barrios J, Pohl MB, Davis IS. A 3D kinematic comparison between single-belt and split-belt treadmill walking. Poster Presentation. North American Congress on Biomechanics, Ann Arbor, MI, 2008
  28. Altman AR, Pohl MB, Davis IS. A Comparison of Split-Belt and Single Belt Treadmill Walking Over Time. Podium Presentation. American College of Sports Medicine, Indianapolis, IN, 2008
  29. Miller TL, Zhu Y, Altman AR, Dysart K, Wolfson MR, Shaffer TH. Mechanical ventilation of the neonatal airway: Sequential changes in mechanical properties and concomitant marker of tissue modeling. PAS 2006: 59: 467
  30. Miller TL, Altman AR, Tsuda T, Shaffer TH. A novel ultrasound imaging method for the in vivo evaluation of kinetics and mechanics in the ventilated neonatal trachea. Proceedings of the American Thoracic Society 3:A679, 2006