Perelman School of Medicine at the University of Pennsylvania

McKay Orthopaedic Research Laboratory

Liu Laboratory

Welcome to Liu Laboratory

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Our research program focuses on biological processes in bone and on how they influence bone material, microstructural, and biomechanical properties with aging, disease, and therapies.

We utilize state-of-the-art imaging, image analysis, and mechanical modeling techniques to explore the mechanisms affecting mechanical functions of skeletons at different length scales in both animal models and clinical investigations. The ultimate goal of our lab is to translate the technologies and research findings from bench side to bedside to improve the diagnostic and therapeutic strategies for osteoporosis and other bone diseases.