Mauck Laboratory

What's New

Congrats to Sylvia, Brendan, and the rest of the Animo team!
July 20, 2018
Congrats to Sylvia, Brendan, and the rest of the Animo team for their publication "A Wearable Magnet-Based System to Assess Activity and Joint Flexion in Humans and Large Animals” accepted for publication in Annals of Biomedical Engineering!

Congrats to Anthony Martin!
June 25, 2018
Congrats to Anthony Martin and co-workers for winning the top poster award at the 2018 Ortho Research Day!

Acellular Hyaluronic Acid Scaffold with Growth Factor Delivery for Cartilage Repair in a Large Animal Model
Martín AR, Patel JM, Eby MR, Sennett ML, Davidson MD, Carey JL, Burdick JA, Mauck RL

Congratulations to Spence Szczesny!
February 12, 2018
Congrats to Spence for his paper entitled “Fatigue Loading of Tendon Results in Collagen Kinking and Denaturation but Does Not Change Local Tissue Mechanics” accepted for publication in the Journal of Biomechanics!

Congrats to Sarah Gullbrand and the DAPS team!
February 05, 2018
Congrats to Sarah Gullbrand and the DAPS team for their paper entitled “Towards the Scale up of Tissue Engineered Intervertebral Discs for Clinical Application” accepted for publication in Acta Biomaterialia!

Congrats to Sylvia Qu
February 01, 2018
Congrats to Sylvia Qu and colleagues for their paper entitled “Maturation State and Matrix Microstructure Regulate Interstitial Cell Migration in Dense Connective Tissues” accepted for publication in Scientific Reports!

Congrats to Sonia Bansal
December 18, 2017
Congrats to Sonia Bansal for completing her thesis proposal!

Congrats to Minwook Kim
November 24, 2017
Congrats to Minwook Kim for his paper entitled "Role of Dexamethasone in the Long-Term Functional Maturation of MSC-Laden Hyaluronic Acid Hydrogels for Cartilage Tissue Engineering” accepted for publication in the Journal of Orthopaedic Research!

Congrats to Eddie Bonnevie
November 16, 2017
Congrats to Eddie Bonnevie for an excellent score on his F32 Application! Way to go Eddie!

Congrats to Minwook Kim
November 16, 2017
Congrats to Minwook Kim for being selected as New Investigator Recognition Award (NIRA) Finalist at the 2018 Orthopaedic Research Society Meeting! Congrats Minwook!

Congrats to Su Chin Heo
November 16, 2017
Congrats to Su Chin Heo for being selected as New Investigator Recognition Award (NIRA) Finalist at the 2018 Orthopaedic Research SocietyMeeting! Congrats Su Chin!

Congrats to Sylvia Qu and Julianne Holloway
November 13, 2017
Congrats to Sylvia Qu and Julianne Holloway for having their manuscript entitled “Programmed Biomolecule Delivery to Enable and Direct Cell Migration for Connective Tissue Repair” accepted for publication in Nature Communications!

Congrats to John Martin and the DAPS team
November 13, 2017
Congrats to John Martin and the DAPS team for having their manuscript entitled “In Vitro Maturation and In Vivo Integration and Function of an Engineered Cell-Seeded Disc-like Angle Ply Structure (DAPS) for Total Disc Arthroplasty"accepted for publication in Scientific Reports!

Congrats to Su Chin, Spence, and Dong Hwa!
October 09, 2017
Congrats to Su Chin, Spence, and Dong Hwa for their manuscript entitled "Expansion of Mesenchymal Stem Cells on Electrospun Scaffolds Maintains Stemness, Mechano-Responsivity, and Differentiation Potential”, accepted for publication in the Journal of Orthopaedic Research!

Congrats to Claire McLeod!
September 13, 2017
Congrats to Claire for her review paper entitled “On the origin and impact of mesenchymal stem cell heterogeneity: New insights and emerging tools for single cell analysis” accepted for publication in the eCM Journal!

Congrats to Eric Dai!
August 23, 2017
Congrats to Eric Dai for passing his qualifying exam!

Congrats to Su Chin, Brian, and Eric!
August 14, 2017
Congrats to Su Chin, Brian, and Eric for having their review paper 'Mechano-Adaptation of the Stem Cell Nucleus’ accepted for publication in the Nucleus! Nice work gents.

Congrats to Sarah Gullbrand!
August 14, 2017
Congrats to Sarah Gullbrand for being awarded a Career Development Award (CDA-1) from the Department of Veterans’ Affairs! Way to go Sarah!

Congratulations to Tonia Tsinman!
June 29, 2017
Congratulations to Tonia Tsinman for winning first place in the MS student paper competition at the 2017 SB3C meeting!!! Way to go!

Congrats to Dr. Brian Cosgrove!
June 12, 2017
Congrats to Dr. Brian Cosgrove for successfully defending his thesis entitled “Engineering Complex Microenvironments to Manipulate and Study Cellular Mechanobiology"on June 5th. Way to go Brian!

Congrats to Dr. Bhavana Mohanraj!
June 12, 2017
Congrats to Dr. Bhavana Mohanraj for successfully defending her thesis entitled “High Throughput and Mechano-Active Platforms to Promote Cartilage Regeneration and Repair” on May 22nd. Way to go Bhav!

Congrats to Sonia, Niobra, Alex, Olivia, Sylvia, Bre, Sai, Rob, and Milt
May 12, 2017
Congrats to Sonia, Niobra, Alex, Olivia, Sylvia, Bre, Sai, Rob, and Milt for their paper “Large Animal Models of Meniscus Repair and Regeneration: A Systematic Review of the State of the Field” accepted for publication in Tissue Engineering, Part C. Great work team!

Congratulations to Claire McLeod
May 12, 2017
Congrats to Dr. Claire McLeod for successfully defending her thesis entitled: Single Cell Molecular Heterogeneity inn Musculoskeletal Differentiation. Way to go Dr. McLeod! Best of luck at Google!

Congratulations to Sarah Gullbrand!
May 01, 2017
Congratulations to Sarah Gullbrand for being awarded a Career Development Award entitled “The Role of the Endplate in Intervertebral Disc Degeneration and Regeneration” from the Rehabilitation Research and Development Service (RR&D) of the Department of Veteran’s Affairs!

Congrats to Eddie, Sarah, Sonia, and Brian
March 29, 2017
Congrats to Eddie, Sarah, Sonia, and Brian for having their abstracts selected for podium presentation at the 2017 SB3C meeting! And to Tonia for being selected as a finalist in the MS Level Poster competition!

Congrats to everyone for the fabulous showing at the 2017 ORS meeting!
March 29, 2017
Congrats to everyone for the fabulous showing at the 2017 ORS meeting! Special shoutout to Sarah Gullbrand and Eddie Bonnevie for winning the New Investigator Recognition Award!

Congratulations to Minwook Kim
February 21, 2017
Congratulations to Dr. Minwook Kim for successfully defending his thesis! A truly Minwookian effort!

Congratulations to Claudia Loebel
February 02, 2017
Congrats to visiting graduate student Claudia Loebel for her paper entitled "Crosslinking Chemistry of Tyramine-Modified Hyaluronan Hydrogels Alters Mesenchymal Stem Cell Early Attachment and Behavior" accepted to BIomacromolecules! Nice work!

Congratulations to Sonia Bansal
January 31, 2017
Congrats to Sonia Bansal for publishing her first manuscript entitled “Mechanical function near defects in an aligned nanofiber composite is preserved by inclusion of disorganized layers: Insight into meniscus structure and function” in Acta Biomaterialia!

Congratulations to Greg Meloni and colleagues
January 31, 2017
Congrats to Greg and colleagues for their paper entitled "Biphasic Finite Element Modeling Reconciles Mechanical Properties of Tissue Engineered Cartilage Constructs Across Testing Platforms," accepted for publication in Tissue Engineering, Part A.

Congratulations to Su Chin Heo
November 30, 2016
Congratulations to Su Chin Heo and coauthors for their paper entitled “Differentiation Alters Stem Cell Nuclear Architecture, Mechanics, and Mechano-Sensitivity” accepted for publication in eLife!

Congratulations to Claire McLeod
November 17, 2016
Congrats to Claire McLeod for her paper "High fidelity visualization of cell-to-cell variation and temporal dynamics in nascent extracellular matrix formation” accepted for publication in Natures Scientific Reports!

Congratulations to Spencer Szczesny
October 28, 2016
Congrats to Spence on his review paper accepted for publication in the Journal of Biomechanical Engineering!

Congrats to Robert Mauck, Jason Burdick, and Brian Cosgrove
September 06, 2016
Congratulations to Robert Mauck, Jason Burdick, and Brian Cosgrove for the development of a biomaterial that enables the study of how stem cells sense stiffness.

Congratulations to Sarah Gullbrand and co-authors!
August 17, 2016
Congratulations to Sarah Gullbrand and co-authors for their paper entitled “A Large Animal Model that Recapitulates the Spectrum of Human Intervertebral Disc Degeneration’ accepted for publication in Osteoarthritis and Cartilage!

Congratulations to Brian Cosgrove and co-authors!
August 15, 2016
Congrats to Brian Cosgrove and co-authors for their paper titled "N-cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells" accepted for publication in Nature Materials.

Congratulations to Tonia Tsinman
July 11, 2016
Congrats to Tonia Tsinman for passing her qual exam!

Congratulations to Su Chin Heo and co-authors
July 11, 2016
Congrats to Su Chin Heo and co-authors for their paper entitled “Mechanically Induced Chromatin Condensation Requires Cellular Contractility in Mesenchymal Stem Cells” now accepted for publication in the Biophysical Journal!

Congratulations to Sonia Bansal
July 05, 2016
Congrats to Sonia Bansal for taking 3rd place in the MS level student paper competition (cell and tissue mechanics) at the SB3C meeting!

Congratulations to Bhavana Mohanraj
July 05, 2016
Congrats to Bhavana Mohanraj for taking 1st place in the PhD level student paper competition (microfluidics and sensing) at the SB3C meeting!

Congratulations to Brian Cosgrove
July 05, 2016
Congrats to Brian Cosgrove for taking 1st place in the PhD level student paper competition (mechanosensing and mechanics) at the SB3C meeting!

Congratulations to John Martin and co-authors!
May 18, 2016
Congrats to John Martin and co-authors for their paper “In vivo performance of an acellular disc-like angle ply structure (DAPS) for total disc replacement in a small animal model", now in press at the Journal of Orthopedic Research.

Congratulations to Sarah Gullbrand and co-authors!
May 18, 2016
Congrats to Sarah Gullbrand and co-authors for their paper "Correlations Between Quantitative T2 and T1ρ MRI, Mechanical Properties and Biochemical Composition in a Rabbit Intervertebral Disc Degeneration Model" now in press at the Journal of Orthopedic Research.

Congratulations to Beth Ashinsky
April 18, 2016
Congrats to Beth Ashinsky for being awarded the 2016 Alpha Omega Alpha Carolyn L. Kuckein Student Research Fellowship. Welcome back to the lab — we missed you!

Congrats to Claire McLeod and Ally Cote
March 28, 2016
Congrats to Claire and Ally for their paper entitled "Single cell differences in matrix gene expression do not predict matrix deposition” published in Nature Communications!

Congratulations to Su Chin Heo and Woojin Han
January 15, 2016
Congrats to Su Chin Heo and Woojin Han for having their recent paper highlighted in the Penn News Today!

Congrats to Woojin Han and Su Chin Heo
January 05, 2016
Congratulations to Woojin Han and Su Chin Heo for their paper 'Microstructural heterogeneity directs micromechanics and mechanobiology in native and engineered fibrocartilage’ now published in Nature Materials. Nice work!

Congratulations to Vishal Saxena and the Cartilage Tissue Engineering Group
January 05, 2016
Congrats to Vishal Saxena and the Cartilage Tissue Engineering Group for their manuscript accepted to Tissue Engineering Part A entitled "Anatomic Mesenchymal Stem Cell-Based Engineered Cartilage Constructs for Biologic Total Joint Replacement".

Congratulations to Brian Cosgrove and Su Chin Heo
December 01, 2015
Congratulations to Brian Cosgrove and Su Chin Heo for having their submissions selected for the Fellow/Student Award at the 2016 Cell and Molecular Bioengineering Meeting! Nice work guys!

Congrats to Su Chin Heo, Sylvia Qu, and John Martin
November 16, 2015
Congrats to Su Chin Heo, Sylvia Qu, and John Martin for successfully completing their PhD Thesis Dissertation Defenses!

Congratulations to Su Chin Heo
November 16, 2015
Congrats to Su Chin Heo for receiving the Best Oral Presentation Award for his presentation titled "Cell contractility established by RhoA/Rock and TGFB/BMP signaling mediates load induced chromatin condensation in MSCs" at the International Biomedical Engineering Conference 2015!

Congrats to Su Chin Heo, Stephen Thorpe, and Tristan Driscoll
October 28, 2015
Congrats to Su Chin Heo, Stephen Thorpe, and Tristan Driscoll for their paper entitled “Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells" accepted for publication in Scientific Reports!

Congrats to Christian Pfeifer, Matt Fisher, Jim Carey, and Rob Mauck
October 23, 2015
Congrats to Christian Pfeifer, Matt Fisher, Jim Carey, and Rob Mauck for their publication in Science Translational Medicine entitled "The Impact of Guidance Documents on Translational Large Animal Studies of Cartilage Repair”. Nice work guys!

Congrats to Xuan Cao and Tristan Driscoll
August 31, 2015
Congrats to Xuan Cao from the Shenoy lab and Tristan Driscoll for their publication entitled "A chemo-mechanical model for extracellular matrix and nuclear rigidity regulated size of focal adhesion plaques" accepted for publication in the Biophysical Journal!

Congratulations to Claire McLeod
August 26, 2015
Congrats to Claire McLeod for successfully completing her thesis proposal! Way to go Claire!

Congrats to Iris Kim, Christian Pfeifer, Matt Fisher, Vishal Saxena, Greg Meloni, Michelle Kwon, and Minwook Kim
August 05, 2015
Congrats to Iris Kim, Christian Pfeifer, Matt Fisher, Vishal Saxena, Greg Meloni, Michelle Kwon, and Minwook Kim for their paper entitled “Fibrous Scaffolds with Varied Fiber Chemistry and Growth Factor Delivery Promote Repair in a Porcine Cartilage Defect Model,” accepted for publication in Tissue Engineering, Part A!

Congratulations to John Martin
August 05, 2015
Congrats to John Martin and co-authors for their paper "A Radiopaque Electrospun Scaffold for Engineering Fibrous Musculoskeletal Tissues: Scaffold Characterization and In Vivo Applications" accepted for publication in Acta Biomaterialia!

Congratulations to Sylvia Qu and John Martin
June 22, 2015
Congrats to Sylvia Qu and John Martin for winning 1st and 2nd place in the Cell and Tissue Engineering PhD Student Paper Competition at the SB3C Meeting!

Congratulations to Harvey Smith
May 15, 2015
Congratulations to Harvey Smith for being awarded a PCMD Pilot Grant for 2015-2016. Way to go Spine Team!

Congratulations to Tristan Driscoll, Brian Cosgrove, Su Chin Heo, and Zach Shurden
May 13, 2015
Congrats to Tristan Driscoll, Brian Cosgrove, Su Chin Heo, and Zach Shurden for the acceptance of their paper "Cytoskeletal to Nuclear Strain Transfer Regulates YAP Signaling in Mesenchymal Stem Cells with Dynamic Loading" to the Biophysical Journal!

Congratulations to John Martin
May 06, 2015
Congratulations to John Martin for being selected as a winner of the 2015 "Art in Science" competition!

Congratulations to Robert L. Mauck
May 06, 2015
Congratulations to Robert L. Mauck, PhD for his appointment as Director of McKay Orthopaedic Research Laboratory!

Congratulations to Claire McLeod
April 05, 2015
Congratulations to Claire McLeod for winning a scholarship and travel award to attend the Summer Institute for Statistics in Big Data, held at the University of Washington!

Welcome to Breanna Seiber
March 26, 2015
Welcome to new Research Engineer Breanna Seiber!

Congratulations to Matt Fisher
February 10, 2015
Congrats to Matt Fisher for his paper entitled "Engineering Meniscus Structure and Function via Multi-layered Mesenchymal Stem Cell-seeded Nanofibrous Scaffolds" accepted for publication in a Special Issue on the topic of the Meniscus in the Journal of Biomechanics!

Congratulations to Dr. Milt Zgonis
February 03, 2015
Congrats to Dr. Milt Zgonis for his OREF New Investigator Grant on strain transfer in native and engineered meniscus being funded!

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