Perelman School of Medicine at the University of Pennsylvania

McKay Orthopaedic Research Laboratory

Mauck Laboratory

Christian Pfeifer

Christian Pfeifer

Post-Doctoral Fellow
University of Pennsylvania

Hometown: Regensburg, Germany

Education: German Board Certification in emergency medicine, 2012
Doctoral Thesis, Institute of Pathology, Ludwig-Maximilians-University Munich, 2008
Medical Degree Ludwigs-Maximilians-University Munich, 2007

Areas of Special Interest: Christian joined the Mauck lab in April 2013. His research is focused on cartilage and meniscal regeneration and prevention of cartilage hypertrophy. In addition to working with the Mauck lab, Christian has been a member of the research group of Prof. Angele (University of Regensburg) since January 2008 with focus on regeneration of cartilage and meniscus under mechanobiological influence. Research focus: terminal differentiation and biomechanical influence on terminal differentiation of chondrogenic differentiated MSCs and articular chondrocytes; translational research of in vitro cartilage repair.

Publications:
Karl A, Olbrich W, Pfeifer C, Zellner J, Berner A, Gehmert S, Prantl L, Angele P, Nerlich M, Mueller MB: Thyroid hormone-induced hypertrophy in mesenchymal stem cell (MSC) chondrogenesis is mediated by bone borphogenetic protein-4 (BMP-4), submitted

Zellner J, Hierl K, Mueller M, Pfeifer C, Berner A, Dienstknecht T, Krutsch W, Geis S, Gehmert S, Kujat R, Dendorfer S, Prantl L, Nerlich M, Angele P: Stem cell-based tissue-engineering for treatment of meniscal tears in the avascular zone. J Biomed Mater Res Part B 2013, Apr:00B:000-000.

Geis S, Gehmert S, Lamby P, Zellner J, Pfeifer C, Prantl L, Jung EM. Contrast enhanced ultrasound (CEUS) and time intensity curve (TIC) analysis in compartment syndrome: First results. Clin Hemorheol Microcirc. 2012 Jan 1;50(1):1-11.

Pfeifer C, Berner A, Mueller MB, Prantl L, Dendorfer S, Englert C: Cartilage labeling for mechanical testing in t-peel configuration; Int Orthop. 2012 Jul;36(7):1493-9

Prantl L, Pfeifer C, Geis S, Gosau M, Jung EM: Osteocutaneous free flaps: a critical analysis of quantitative evaluation of bone microcirculation with contrast-enhanced high resolution ultrasound (hrCEUS) and TIC analysis. Clin Hemorheol Microcirc. 2011; 49(1-4):251-9.

Berner A, Reichert JC, Müller MB, Zellner J, Pfeifer C, Dienstknecht T, Nerlich M, Sommerville S, Dickinson IC, Schütz MA, Füchtmeier B: Treatment of long bone defects and non-unions: from research to clinical practice; Cell Tissue Res. 2011 May 17. [Epub ahead of print]

Mueller F, Pfeifer C, Kinner B, Englert C, Nerlich M, Neumann C: Post-traumatic fulminant paradoxical fat embolism syndrome in conjunction with asymptomatic atrial septal defect: a case report and review of the literature; Journal of Medical Case Reports 2011, 5:142

Pfeifer C, Diebold J: Gene Expression Analysis of Serous Ovarian Carcinoma Using an In-house Customized cDNA-Microarray"; Pathol. Res. Pract. 202(2006)4; p. 227 (Abstract)

Invited Talks and Conference Talks:
Evaluation of microcirculation of osteocutaneous free flaps using high resolution linear contrast enhanced ultrasound (CEUS) and PET-CT: first results; Pfeifer C. (Regensburg), Geis S., Krutsch W., Strobel D., Prantl L., Jung E.M.; Deutscher Kongress für Orthopädie und Unfallchirurgie, Berlin (10/2012)

New visualization methods for evaluation of bone microcirculation; 31st Annual meeting Deutsche Gesellschaft für Mikrozirkulation und Hämorheologie; Halle, Juni 2012

Return to sports after shoulder luxation; 9th Sportmedizinisches Winterseminar (3/12), Obertauern, Austria

Injuries to the AC-joint - diagnostics, therapeutic options and ability for sports; 9th Sportmedizinisches Winterseminar (3/12), Obertauern, Austria

Table instructor: F.A.M.E. (Forum for advanced medical education); Arthroskopische und offene Sprunggelenkschirurgie - Operationskurs an Humanpräparaten; Salzburg, Austria, (11/11)

Osteoporosis – matter of time?; 8th Sportmedizinisches Winterseminar Bad Hofgastein, Austria (3/11) Fluid uptake during competition: new trends in sports nutrition; 8th Sportmedizinisches Winterseminar Bad Hofgastein, Austria (3/11)

Digestion, metabolism and hormones during sport exercise; 7th Sportmedizinisches Winterseminar Bad Hofgastein, Austria (3/10)

Typical sport injuries in adolescent: around the ankle; 7th Sportmedizinisches Winterseminar Bad Hofgastein, Austria (3/10)

Gene Expression Analysis of Serous Ovarian Carcinoma Using an In-house Customized cDNA-Microarray; 90. Jahrestagung der deutschen Gesellschaft für Pathologie in Berlin (4/2006)

Posters:
Evaluation of osseous microvascularization after ostecutaneous free flaps using contrast enhanced ultrasound and PET-CT, Pfeifer, C.; Geis, S.; Krutsch W.; Strobel, D.; Nerlich, M.; Jung, E.M.; Prantl, L., 89th Jahrestagung der bayerischen Chirurgen, Regensburg (7/2012)

Transplantation of a free osteocutaneous parascapular flap for stabilisation oft he thorax after complete loss oft he sternum (5-year follow up) Pfeifer C., Gehmert S., Prantl L., Nerlich M., Deutscher Kongress für Orthopädie und Unfallchirurgie, Berlin (10/2010)