McKay Orthopaedic Research Laboratory > Elliott Lab > John Boxberger

John Boxberger

Graduate Student in Bioengineering
University of Pennsylvania

HOMETOWN
Watertown, New York

EDUCATION
B.S. Biomedical Engineering 2003, Rensselaer Polytechnic Institute

AREAS OF SPECIAL INTERESTS
John has been working towards his Ph.D. in the McKay lab since September of 2003. He joined the lab with a background in orthopaedics, as he studied relationships between aging and bone mechanics during his undergraduate education at Rensselaer Polytechnic Institute. He is currently working to model human intervertebral disc degeneration in rodents. Once established, his model will allow for study of the degenerative pathway as well as potential therapeutic options. Additionally John is working on characterizing structure-function relationships within the intervertebral disc, allowing for a better understanding of the biochemical and biomechanical changes which occur during degeneration.

PUBLICATIONS

1. Boxberger JI, Auerbach JD, Sen S, Elliott DM. An in vivo model of reduced nucleus pulposus glycosaminoglycan content in the rat lumbar intervertebral disc. Spine. 2007. IN PRESS.
2. Boxberger JI, Sen S, Yerramalli CS, Elliott DM. Nucleus Pulposus Glycosaminoglycan Content is Correlated with Axial Mechanics in Rat Lumbar Motion Segments. Journal of Orthopaedic Research. 2006 Sept; 24(9): 1906-15

CONFERENCE PAPERS

1. Boxberger JI , Auerbach JD, Sen S, Dodge GR, Elliott DM. Intervertebral Disc Function is Restored in an In Vivo Model of Chronic Nucleus Pulposus Glycosaminoglycan Reduction in Transactions of the American Society of Mechanical Engineers, 2008 (submitted).
2. Sen S, Boxberger JI , Schroeder Y, Espinoza Orías AA, Elliott DM. Effect of Degeneration on the Dynamic Viscoelastic Properties of Human Annulus Fibrosus in Tension in Transactions of the American Society of Mechanical Engineers, 2008 (submitted).
3. Boxberger JI, Auerbach JD, Sen S, Elliott DM. An In Vivo Model of Reduced Nucleus Glycosaminoglycan in the Rat Lumbar Disc. Transactions of the Orthopaedic Research Society. 32: 1118, 2007.
4. Beckstein JC, Espinoza Orias AA, Cloyd JM, Boxberger JI, Vresilovic EJ, Elliott DM. Axial and Torsion Disc Mechanics for Several Animals Compared to the Human Disc. Transactions of the Orthopaedic Research Society. 32: 1141, 2007.
5. Boxberger JI, Auerbach JD, Sen S, Elliott DM. A New In Vivo Model of Disc Degeneration in the Rat Lumbar Spine. Proceedings of the ASME Summer Bioengineering Conference. 157648, 2006.
6. Boxberger JI, Sen S, Yerramalli CS, Elliott DM. Nucleus Pulposus Glycosaminoglycan Content is Correlated with Axial Mechanical Behavior in Rat Lumbar Intervertebral Disc Motion Segments. Transactions of the Orthopaedic Research Society. 31: 1229, 2006.
7. Boxberger JI, Sen S, Auerbach JD, Yerramalli CS, Elliott DM. Glycosaminoglycan content Affects Intervertebral Disc Neutral Zone Mechanics in Axial Loading. Proceedings of the Biomedical Engineering Society. 142192, 2005.
8. Favata M, Beredjiklian PK, Beason DP, Pedowitz DI, Andarawis NA, Boxberger JI, Soslowsky LJ: The Effect of Environment on Adult and Fetal Tendon Healing. Proceedings of the Biomedical Engineering Society. 2004.
9. Boxberger JI, Vashishth D. Nonenzymatic Glycation Affects Bone Fracture by Modifying Creep and Inelastic Properties of Collagen. Transactions of the Orthopaedic Research Society. 29: 0491, 2004.