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McKay Orthopaedic Research Laboratory > Elliott Lab > Nandan Nerurkar

Nandan Nerurkar

Graduate Student in Mechanical Engineering University of Pennsylvania

HOMETOWN
Edmond, OK

EDUCATION
M.S. in Biomedical Engineering 2005, Washington University, St. Louis
B.S. in Biological Engineering 2003, University of Maryland, College Park

AREAS OF SPECIAL INTERESTS
Nandan has been working with Dr. Robert Mauck and Dr. Dawn Elliott in the McKay Orthopaedic Research Lab since the Fall of 2005. His research is focused on the application of stem cells for tissue engineering of the intervertebral disc, with particular emphasis on the annulus fibrosus.

In his spare time, Nandan enjoys cheering on the Phillies while drinking well-hopped ales. Between baseball seasons, Nandan enjoys re-watching Big Trouble in Little China and drinking doppelbocks.

PUBLICATIONS

  1. Nerurkar NL, Elliott DM, Mauck RL. Mechanical design criteria for intervertebral disc tissue engineering. Journal of Biomechanics (submitted).
  2. Nerurkar NL, Baker BM, Sen S, Wible EW, Elliott DM, Mauck RL. Nanofibrous biologic laminates replicate the form and function of the annulus fibrosus. Nature Materials doi:10.1038/nmat2558.
  3. Nerurkar NL, Sen S, Huang AH, Elliott DM, Mauck RL. Engineered disc-like angle-ply structures for intervertebral disc replacement. Spine Special Issue (submitted).
  4. Baker BM, Nerurkar NL, Burdick JA, Elliott DM, and Mauck RL. Fabrication and Modeling of Dynamic Multi-Polymer Nanofibrous Scaffolds. Journal of Biomechanical Engineering (in press).
  5. Mauck RL, Baker BM, Nerurkar NL, Burdick JA, Li WJ, Tuan RS, Elliott DM. Engineering on the straight and narrow: the mechanics of nanofibrous assemblies for fiber-reinforced tissue regeneration. Tissue Engineering Part B Review, 2009.
  6. Nerurkar NL, Mauck RL, Elliott DM. ISSLS prize winner: Integrating theoretical and experimental methods for functional tissue engineering of the annulus fibrosus. Spine, 33(25), 2008.
  7. Ramasubramanian A, Nerurkar NL, Achtien KH, Filas BA, Voronov DA, Taber LA. On the modeling morphogenesis of the looping heart following mechanical perturbation. Journal of Biomechanical Engineering, 130(6), 2008.
  8. Nerurkar NL, Elliott DM, Mauck RL. Mechanics of oriented elecctrospun nanofibrous scaffolds for annulus fibrosus tissue engineering. Journal of Orthopaedic Research, 25(8), 2007.
  9. Nerurkar NL, Ramasubramanian A, Taber LA. Morphogenetic Adaptation of the Looping Embryonic Heart to Altered Mechanical Loads. Developmental Dynamics, 235(7), 2006.
  10. Wagenseil JE, Nerurkar NL, Knutsen RH, Okamoto RJ, Li DY, Mecham RP. Effects of elastin haploinsufficiency on the mechanical behavior of mouse arteries. Am J Physiol Heart Circ Physiol, 289 (3), 2005.
  11. Anderson GP, Nerurkar NL. Improved fluoroimmunoassays using the dye Alexa Fluor 647 with the RAPTOR, a fiber optic biosensor. Journal Of Immuunological Methods, 271 (1-2), 2002.
CONFERENCE PAPERS
  1. Nerurkar NL, Sen S, Baker BM, Zachry TL, Elliott DM, Mauck RL. Dynamic culture enhances stem cell ingress and extracellular matrix deposition on electrospun nanofibrous scaffolds. 56th Annual Meeting of the Orthopaedic Research Society, New Orleans, March 6 – 9, 2010 (submitted).
  2. Nerurkar NL, Sen S, Huang AH, Elliott DM, Mauck RL. Functional maturation of composites that mimic the hierarchical organization of the intervertebral disc. 56th Annual Meeting of the Orthopaedic Research Society, New Orleans, March 6 – 9, 2010 (submitted).
  3. Nerurkar NL, Sen S, Mauck RL, Elliott DM. Selective removal of extracellular matrix components reveals homologous structure-function relationships between engineered and native fibrocartilage. 56th Annual Meeting of the Orthopaedic Research Society, New Orleans, March 6 – 9, 2010 (submitted).
  4. Nathan AS, Baker BM, Nerurkar NL, Mauck RL. Time-dependent and anisotropic nuclear deformations on aligned nanofibrous scaffolds. 56th Annual Meeting of the Orthopaedic Research Society, New Orleans, March 6 – 9, 2010 (submitted).
  5. Nerurkar NL, Mauck RL, Elliott DM. Alternating Fiber Orientation Enhances the Functional Growth of Nanofibrous Laminates for Annulus Fibrosus Tissue Engineering. BMES 2009 Annual Fall Scientific Meeting. Pittsburgh PA, October 7-10, 2009.
  6. Nerurkar NL, Sen S, Wible EW, Stambough JB, Elliott DM, Mauck RL. Mesenchymal Stem Cell Seeded Nanofibrous Laminates Mimic the Multi-scale Form and Function of the Annulus Fibrosus. ASME Summer Bioengineering Conference. Lake Tahoe, CA. June 17-21, 2009.
  7. Nerurkar NL, Sen S, Mauck RL, Elliott DM. Bilamellar Engineered Constructs Mimic Form and Function of the Native Annulus Fibrosus. Annual Meeting of the International Society for the Study of Lumbar Spine. Miami FL. May 4-9, 2009.
  8. Nerurkar NL, Sen S, Wible EE, Stambough JB, Elliott DM, Mauck RL. MSC-Seeded Nanofibrous Laminates Mimic Multi-Scale Form and Function of the Annulus Fibrosus. 55th Annual Meeting of the Orthopaedic Research Society, Las Vegas, NV, February 22-25, 2009.
  9. Baker BM, Nerurkar NL, Burdick JA, Elliott DM, Mauck RL . Instilling Time-Dependent Behavior in Electrospun, Multi-Polymer Nanofibrous Composites. 55th Annual Meeting of the Orthopaedic Research Society, Las Vegas, NV, February 22-25, 2009.
  10. Baker BM, Nerurkar NL, Burdick JA, Mauck RL. The Temporal Behavior of Electrospun, Multi-Polymer Nanofibrous Composites. Proceedings of TERMIS-NA 2008 Conference, San Diego, CA, December 7-11, 2008.
  11. Baker BM, Nerurkar NL, Burdick JA, Elliott DM, Mauck RL. "Fabrication and Modeling of an Electrospun Tri-Polymer Composite for the Engineering of Fibrous Tissues," Proceedings of ASME 2008 Summer Bioengineering Conference, Marco Island, FL, June 25-29, 2008.
  12. Nerurkar NL, Mauck RL, Elliott DM. Integrating theoretical and experimental methods for functional tissue engineering of the annulus fibrosus. 35th Annual Meeting of the International Society for the Study of Lumbar Spine, Geneva, Switzerland, May 28-31, 2008.
  13. Nerurkar NL, Nguyen AM, Mauck RL, Elliott DM. Functional evolution of engineered annulus fibrosus using constitutive modeling. 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, March 2-5, 2008.
  14. Nerurkar NL, Orlansky AS, Sen S, Elliott DM, Mauck RL. Multiscale tissue engineering of the intervertebral disc. 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, March 2-5, 2008.
  15. Lake SP, Nerurkar NL, Mauck RL, Kaldowec JA, Elliott DM, Soslowsky LJ. Development of a Nonlinear Anisotropic Fiber Dispersion Model to Quantify and Predict Mechanics of Normal and Injured Tendon. 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, March 2-5, 2008.
  16. Nerurkar NL, Elliott DM, Mauck RL. Architecture of nanofibrous scaffolds influences fibrocatilagenous gene expression of annulus fibrosus and mesenchymal stem cells. 6th Combined meeting of the Orthopaedic Research Society, Honolulu, Hawaii, Oct. 20-24, 2007
  17. Nerurkar NL, Nguyen AM, Tsing P, Mauck RL, Elliott DM. A hyperelastic fiber-reinforced continuum model to assay functional evolution of tissue engineered annulus fibrosus. 6th Combined meeting of the Orthopaedic Research Society, Honolulu, Hawaii, Oct. 20-24, 2007
  18. Taber LA, Nerurkar NL, Ramasubramanian A. Finite element modeling of the looping embryonic heart including mechanical feedback. 9th US National Congress on Computational Mechanics, San Francisco, CA, July 22-26, 2007.
  19. Ramasubramanian A, Nerurkar NL, Taber LA. Role of mechanical feedback in restoration of normal cardiac c-looping following perturbed loading. 2007 Summer Bioengineering Conference, Keystone, CO, June 20-24
  20. Nerurkar NL, Nguyen AM, Elliott DM, Mauck RL. Annulus Fibrosus tissue engineering with aligned electrospun nanofibrous scaffolds. 53rd Annual Meeting of the Orthopaedic Research Society, San Diego, CA, February 11-14, 2007
  21. Nerurkar NL, Baker BM, Elliott DM, Mauck RL. Engineering of fiber- reinforced tissues with anisotropic biodegradable nanofibrous scaffolds. 2006 IEEE-EMBS Meeting, New York, NY, Aug 30-Sept 3
  22. Nerurkar NL, Ramasubramanian A, Taber LA. Morphogenetic adaptation of the embryonic heart to perturbed loading. 2006 ASME Summer Bioengineering Conference, Amelia Island, FL, June 21-25

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