McKay Orthopaedic Research Laboratory > Elliott Lab > Lachlan J. Smith, Ph.D.

Lachlan J. Smith, Ph.D.

Post-Doctoral Fellow
University of Pennsylvania

HOMETOWN
Adelaide, South Australia

EDUCATION
Ph.D. Bioengineering, 2008, University of Adelaide
B.E. (Hons) Mechatronic Engineering, 2001, University of Adelaide

AREAS OF SPECIAL INTERESTS
Structure, function and pathology of the intervertebral disc

PUBLICATIONS

1. Smith LJ, Martin JT, Szczesny SE, Ponder KP, Haskins ME, Elliott DM (2009) Structural and biomechanical foundations of lumbar spine deformity in mucopolysaccharidosis type VII. J Orthop Res (in press)
2. Smith LJ, Fazzalari NL (2009) The elastic fibre network of the human lumbar anulus fibrosus: structure, function and potential role in progression of intervertebral disc degeneration. Eur Spine J (in press)
3. Kurmis AP, Slavotinek JP, Barber C, Smith LJ, Fazzalari NL (2008) An unusual MR signal reduction artifact in an incompletely thawed cadaver spine specimen. Radiography (in press)
4. Norman J, Shapter JG, Short L, Smith LJ, Fazzalari NL (2008) Micromechanical properties of human trabecular bone: a hierarchical investigation using nanoindentation. J Biomed Mater Res A, 87:196-202
5. Smith LJ, Byers S, Costi JJ, Fazzalari NL (2008) Elastic fibers enhance the mechanical integrity of the human lumbar anulus fibrosus in the radial direction. Ann Biomed Eng, 36:214-23
6. Smith LJ, Fazzalari NL (2006) Regional variations in the density and arrangement of elastic fibres in the anulus fibrosus of the human lumbar disc. J Anat, 209:359-67

PATENTS
Glasson JH, Smith LJ (2005) Microbial streaking device. United States Patent 20070202564.

CONFERENCE PROCEEDINGS

1. Smith LJ, Martin JT, Szczesny SE, Ponder KP, Haskins ME, Elliott DM (2009) Mucopolysaccharidosis VII and the developing lumbar spine: consequences for annulus fibrosus and vertebral end plate mechanical properties, American Society of Mechanical Engineers Summer Bioengineering Conference, Lake Tahoe, USA
2. Smith LJ, Martin JT, Ponder KP, Haskins ME, Elliott DM (2009) Structural and mechanical consequences of mucopolysaccharidosis VII for the developing lumbar spine, International Society for the Study of the Lumbar Spine Annual Meeting, Miami, USA
3. Smith LJ, Schirer JP, Dickinson ME, Fazzalari NL (2009) The influence of degree of mineralisation on the micromechanical properties of discrete remodelling packets in non-diseased human trabecular bone spicules, 55th Annual Meeting, Orthopaedic Research Society, Las Vegas, USA
4. Smith LJ, Kurmis AP, Slavotinek JP, Fazzalari NL (2009) Evaluation of a manganese chloride phantom-based magnetic resonance imaging technique as a quantitative tool for predicting human lumbar intervertebral disc condition, 55th Annual Meeting, Orthopaedic Research Society, Las Vegas, USA
5. Smith LJ, Schirer JP, Dickinson ME, Fazzalari NL (2008) Relationships between mineralisation and micromechanical properties within the individual remodelling packets of human femoral trabecular bone spicules, Annual Scientific Meeting, Australian Society for Medical Research SA Branch, Adelaide, Australia.
6. Smith LJ, Schirer JP, Dickinson ME, Fazzalari NL (2008) Relationships between mineralisation and micromechanical properties within the individual remodelling packets of human femoral trabecular bone spicules, 5th Clare Valley Bone Meeting, Clare, Australia.
7. Smith LJ, Fazzalari NL (2008) Structural changes to the human lumbar anulus fibrosus elastic fibre network following radial tensile deformation, 54th Annual Meeting, Orthopaedic Research Society, San Francisco, USA.
8. Costi JJ, Stanley RM, Smith LJ, Tettis H, Tsangari H, Hearn TC, Fazzalari NL (2008) The effect of intervertebral disc degeneration on vertebral cortical strains and disc mechanical properties, 54th Annual Meeting, Orthopaedic Research Society, San Francisco, USA.
9. Smith LJ, Byers S, Costi JJ, Fazzalari NL (2007) Elastic fibres enhance the mechanical integrity of the anulus fibrosus transverse to the collagen fibre direction, 13th Annual Scientific Meeting, Australian and New Zealand Orthopaedic Research Society, Auckland, New Zealand.
10. Kurmis AP, Slavotinek JP, Barber C, Smith LJ, Fazzalari NL (2007) An unusual MR core signal reduction artefact in an incompletely thawed cadaveric spine specimen, 13th Annual Scientific Meeting, Australian and New Zealand Orthopaedic Research Society, Auckland, New Zealand.
11. Smith LJ, Byers S, Costi JJ, Fazzalari NL (2007) The roles of elastic fibres and glycosaminoglycans in the radial tensile mechanical properties of the human lumbar anulus fibrosus, ASME Summer Bioengineering Conference, Keystone, USA.
12. Smith LJ, Byers S, Costi JJ, Fazzalari NL (2007) The roles of elastic fibres in the radial tensile mechanical properties of the human lumbar anulus fibrosus, Annual Scientific Meeting, Australian Society for Medical Research SA Branch, Adelaide, Australia.
13. Smith LJ, Fazzalari NL (2007) Variations in the density and arrangement of elastic fibres in the anulus fibrosus of the human lumbar disc suggest functional significance, 53rd Annual Meeting, Orthopaedic Research Society, San Diego, USA.
14. Smith LJ, Fazzalari NL (2006) Variations in elastic fibre density and arrangement in the anulus fibrosus of the human lumbar disc. Annual Scientific Meeting, Australian Orthopaedic Association SA Branch, Adelaide, Australia.
15. Smith LJ, Fazzalari NL (2006) Regional variations in elastic fibre density and arrangement in the anulus fibrosus of the human lumbar disc, 12th Annual Scientific Meeting, Australian and New Zealand Orthopaedic Research Society, Canberra, Australia.
16. Smith LJ, Fazzalari NL (2005) Elastic fibre architecture in the human lumbar anulus fibrosus, 29th Annual Meeting, Matrix Biology Society of Australia and New Zealand, Victor Harbor, Australia.