McKay Orthopaedic Research Laboratory >
Soslowsky Lab > Effects of Hypercholesterolemia
Effects of Hypercholesterolemia
Hypercholesterolemia affects an appreciable percentage of adults in the U.S. and represents a significant healthcare problem. The American Heart Association defines hypercholesterolemia as a total serum concentration of 240 mg/dL or higher, with concentrations between 200-239 considered borderline high, and below 200 being optimal. High levels of total cholesterol, triglycerides, and low-density lipoprotein (LDL) have long been associated with a myriad of cardiovascular disorders such as atherosclerosis; however, there are limited data related to their potential effect on the musculoskeletal system. The overall goal of this area of research is to investigate potential relationships between hypercholesterolemia and tendon mechanics by examining:
- Native Tendon Properties
- The Tendon Response to Injury
