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McKay Orthopaedic Research Laboratory > Soslowsky Lab > Louis J. Soslowsky

Louis J. Soslowsky, Ph.D.

Fairhill Professor of Orthopaedic Surgery
Professor of Bioengineering
Vice Chair for Research-Orthopaedic Surgery
Director of McKay Orthopaedic Research Laboratory
Graduate Group Member in Bioengineering and Mechanical Engineering in Applied Mechanics

HOMETOWN
East Brunswick, New Jersey

EDUCATION
Ph.D. Engineering Mechanics, 1991, Columbia University
B.S. Engineering Mechanics, 1986, Columbia University

AREAS OF EXPERTISE
Orthopaedic bioengineering and tissue engineering

AREAS OF SPECIAL INTEREST
Structure-function relationships of tendons and ligaments; models for tendon injury, healing, repair and regeneration; biomechanics of the shoulder and elbow

CURRENT POSITIONS HELD
  1. Research Editor, Journal of Shoulder and Elbow Surgery
  2. Editorial Advisory Board, Journal of Orthopaedic Research
  3. Editorial Consultant Panel, Journal of Biomechanics
  4. Ad Hoc Reviewer, National Institute of Health, several other agencies and foundations
  5. Chairman, Bioengineering Division of the American Society of Mechanical Engineers
  6. Member, United States National Committee on Biomechanics

PRESENT AND RECENT FUNDING
  1. National Institute of Health
  2. Orthopaedic Research and Educational Foundation
  3. Whitaker Foundation
  4. National Science Foundation
  5. Wyeth Research
  6. Biomet, Inc.

RECENT PUBLICATIONS
  1. Skalak, R., Soslowsky, L., Schmalzer, E., Impelluso, T., and Chien, S.: Theory of filtration of mixed blood suspensions. Biorheology, 24:35-52, 1987 (PMID 3651582).
  2. Froimson, M.I., Ateshian, G.A., Soslowsky, L.J., and Mow, V.C.: Quantification of the surfaces and contact areas at the patellofemoral articulation. Proc Instit of Mech Engineers 5:73-78, 1989.
  3. Bigliani, L.U., Ticker, J.B., Flatow, E.L., Soslowsky, L.J., and Mow, V.C.: Die Beziehung von Akromialarchitektur zu Erkrankungen der Rotatorenmanschette. Orthopade 20:302-309, 1991 (PMID 1745540).
  4. Ateshian, G.A., Soslowsky, L.J., and Mow, V.C.: Quantitation of articular surface topography and cartilage thickness in knee joints using stereophotogrammetry. J Biomechanics 24:761-776, 1991 (PMID 1918099).
  5. Bigliani, L.U., Ticker, J.B., Flatow, E.L., Soslowsky, L.J., and Mow, V.C.: The relationship of acromial architecture to rotator cuff disease. Clin Sports Med 10:823-838, 1991 (PMID 1934099).
  6. Bigliani, L.U., Pollock, R.G., Soslowsky, L.J., Flatow, E.L., Pawluk, R.J., and Mow, V.C.: Tensile properties of the inferior glenohumeral ligament. J Orthop Res 10:187-197, 1992 (PMID 1740736).
  7. Soslowsky, L.J., Flatow, E.L., Bigliani, L.U., Pawluk, R.J., and Mow, V.C.: Quantitation of in situ contact areas in the glenohumeral joint: A biomechanical study. J Orthop Res 10: 524-534, 1992 (PMID 1613626).
  8. Soslowsky, L.J., Flatow, E.L., Bigliani, L.U., and Mow, V.C.: Articular geometry of the glenohumeral joint. Clin Orthop Rel Res 185:181-190, 1992 (PMID 1446435).
  9. Ateshian, G.A., Kwak, S.D., Soslowsky, L.J., and Mow, V.C.: A stereophotogrammetric method for determining in situ contact areas in diarthrodial joints, and a comparison with other methods. J Biomechanics 27:111-124, 1994 (PMID 7508940).
  10. Soslowsky, L.J., An, C.H., Johnston, S.P., and Carpenter J.E.: Geometric and mechanical properties of the coracoacromial ligament and their relationship to rotator cuff disease. Clin Orthop Rel Res 304:10-17, 1994 (PMID 8020201).
  11. Derwin, K.A., Soslowsky, L.J., Green, W.D.K., and Elder, S.H.: A new optical system for the determination of deformations and strains: Calibration characteristics and experimental results. J Biomechanics 27:1277-1285, 1994 (PMID 7962015).
  12. Flatow, E.L., Ateshian, G.A., Soslowsky, L.J., Pawluk, R.J., Grelsamer, R.P., Mow, V.C., and Bigliani, L.U.: Computer simulation of glenohumeral and patellofemoral subluxation: Estimating pathological articular contact. Clin Orthop Rel Res 306:28-33, 1994 (PMID 8070206).
  13. Flatow, E.L., Soslowsky, L.J., Ticker, J.B., Hepler, M.D., Ark, J.W., Pawluk, R.J., Bigliani, L.U., and Mow, V.C.: Excursion of the rotator cuff under the acromion: Patterns of subacromial contact. Am J Sports Med 22:779-788, 1994 (PMID 7856802).
  14. Ateshian, G.A., Ark, J.W., Rosenwasser, M.P., Pawluk, R.J., Soslowsky, L.J., and Mow, V.C.: Contact areas in the thumb carpometacarpal joint. J Orthop Res 13:450-458, 1995 (PMID 7602407).
  15. Malicky, D.M, Soslowsky, L.J., and Blasier, R.B.: Anterior glenohumeral stabilization factors: Progressive effects in a biomechanical model. J Orthop Res 14:282-288, 1996 (PMID 8648507).
  16. Ticker, J.B., Bigliani, L.U., Soslowsky, L.J., Pawluk, R.J., Flatow, E.L., and Mow, V.C.: Inferior glenohumeral ligament: Geometric and strain-rate dependent properties. J Shoulder Elbow Surg 5:269-279, 1996 (PMID 8872924).
  17. Soslowsky, L.J., An, C.H., DeBano, C.M., and Carpenter, J.E.: Coracoacromial ligament: In situ load and viscoelastic properties in rotator cuff disease. Clin Orthop Rel Res 330:40-44, 1996 (PMID 8804273).
  18. Soslowsky, L.J., Carpenter, J.E., DeBano, C.M., Banerji, I., and Moalli, M.R.: Development and use of an animal model for investigations on rotator cuff disease. J Shoulder Elbow Surg 5:383-392, 1996 (PMID 8933461).
  19. Blasier, R.B., Soslowsky, L.J., Malicky, D.M., and Palmer, M.L.: Posterior glenohumeral subluxation: Active and passive stabilization in a biomechanical model. J Bone Joint Surg 79-A:433-440, 1997 (PMID 9070535).
  20. Soslowsky, L.J., Carpenter, J.E., Bucchieri, J., and Flatow, E.L.: Biomechanics of the rotator cuff. Orthop Clin North America 28:17-30, 1997 (PMID 9024428).
  21. Soslowsky, L.J., Malicky, D.M., and Blasier R.B.: Active and passive factors in inferior glenohumeral stabilization: A biomechanical model. J Shoulder Elbow Surg 6:371-379, 1997 (PMID 9285877).
  22. Bey, M.J. Elders, G.J., Huston, L.J., Kuhn, J.E., Blasier, R.B., and Soslowsky, L.J.: The mechanism of creation of superior labrum, anterior, and posterior lesions in a dynamic, biomechanical model of the shoulder: The role of inferior subluxation. J Shoulder Elbow Surg, 7:397-401, 1998 (PMID 9752651).
  23. Carpenter, J.E., Flanagan, C.L., Thomopoulos, S., and Yian, E.H., Soslowsky, L.J.: The effects of overuse combined with intrinsic or extrinsic alterations in an animal model of rotator cuff tendinosis. Am J Sports Med, 26:801-807, 1998 (Hughston Award Winner) (PMID 9850782).
  24. Carpenter, J.E., Thomopoulos, S., Flanagan, C.L., DeBano, C.M., Moalli, M.R., and Soslowsky, L.J.: Rotator cuff defect healing: A biomechanical and histologic analysis in an animal model. J Shoulder Elbow Surg, 7:599-605, 1998 (PMID 9883420).
  25. Derwin, K.A. and Soslowsky L.J.: A quantitative investigation of structure-function relationships in a tendon fascicle model. J Biomech Eng, 121:598-604, 1999 (PMID 10633259).
  26. Carpenter, L.J., Thompoulos, S., and Soslowsky, L.J.: Animal models of tendon and ligament injuries for tissue engineering applications. Clin Orthop Rel Res, 367:S296-311, 1999 (PMID 10546654).
  27. Elder, S.H. Kimura, J.H., Soslowsky L.J., and Goldstein S.A.: Effect of compressive loading on chondrocyte differentiation in agarose cultures of chick limb-bud cells. J Orthop Res, 18:79-86, 2000 (PMID 10716282).
  28. Kuhn, J.E., Bey, M.J., Huston, L.J., Blasier, R.B., and Soslowsky, L.J.: Ligamentous Restraints to External Rotation of the Humerus in the late-cocking phase of throwing: A cadaveric biomechanical investigation Am J Sports Med, 28:200-205, 2000 (PMID 10750996).
  29. Soslowsky, L.J., Thomopoulos, S., Tun, S., Flanagan, C.L., Keefer, C.C., Mastaw, J., and Carpenter, J.E.: Overuse activity injuries the supraspinatus tendon in an animal model: A histologic and biomechanical study. J Shoulder Elbow Surgery, 9:79-84, 2000 (Neer Award Winner) (PMID 10810684).
  30. Derwin, K.A., Soslowsky, L.J., Kimura, J.H., and Plaas, A.H.: Proteoglycans and glycosaminoglycan fine structure in the mouse tail tendon fascicle. J Orthop Res, 19:269-277, 2001 (PMID 11347701).
  31. Elder, S.H. Goldstein, S.A., Kimura, J.H., Soslowsky L.J., and Spengler, D.M.: Chondrocyte differentiation is modulated by frequency and duration of cyclic compressive loading. Annals Biomed Eng, 29:476-482, 2001 (PMID 11459341).
  32. Malicky, D.M., Soslowsky, L.J., Mouro, C.M., Frisancho, J.C., Lindholm, S.R., and Kuhn, J.E.: Total strain fields of the antero-inferior shoulder capsule. J Biomech Eng, 123:425-431, 2001 (PMID 11601727).
  33. Abboud, J.A., Bozentka, D.J., Soslowsky, L.J., and Beredjiklian, P.K.: Effect of implant design on the cyclic loading properties of mini suture anchors in carpal bones, J Hand Surg [Am], 27:43-48, 2002 (PMID 11810613).
  34. Bey M.J., Song, H.K., Wehrli, F.W., and Soslowsky, L.J.: A noncontact, nondestructive method for quantifying intratissue deformations and strains. J Biomech Eng, 124:253-258, 2002 (PMID 12002136).
  35. Thomopoulos, S., Hattersley, G., Rosen, V., Mertens, M., Galatz, L., Williams, G.R., and Soslowsky, L.J.: The localized expression of extracellular matrix components in healing tendon insertion sites: An in situ hybridization study. J Orthop Res, 20:454-463, 2002 (PMID 12038618).
  36. Thomopoulos, S., Soslowsky, L.J., Flanagan, C.L., Tun, S., Keefer, C.C., Mastaw, J., and Carpenter, J.E.: The effect of fibrin clot on healing rat supraspinatus tendon defects. J Shoulder Elbow Surg, 11:239-247. 2002 (PMID 12070496).
  37. Abboud, J. and Soslowsky, L.J.: Interplay of the static and dynamic restraints in glenohumeral instability. Clin Orthop Rel Res, 400:48-57, 2002 (PMID 12072745).
  38. Malicky, D.M., Kuhn, J.E., Frisancho, J.C., Lindholm, S.R., Raz, J.A., and Soslowsky, L.J.: Non-recoverable strain fields of the anteroinferior glenohumeral capsule under subluxation. J Shoulder Elbow Surg, 11:529-540, 2002 (2001 Neer Award Winner) (PMID 12469076).
  39. Bey M.J., Song, H.K., Wehrli, F.W., and Soslowsky, L.J.: Intratendinous strain fields of the intact supraspinatus tendon: The effect of glenohumeral joint position and tendon region. J Orthop Res, 20:869-874, 2002 (PMID 12168680).
  40. Soslowsky, L.J., Thomopoulos, S., Esmail, A., Flanagan, C.L., Iannotti, J.P., Williamson III, J.D., and Carpenter, J.E.: Rotator cuff tendinosis in an animal model: The role of extrinsic and overuse factors. Ann Biomed Eng, 30:1057-1063, 2002 (PMID 12449766).
  41. Bey M.J., Ramsey, M.L., and Soslowsky, L.J.: Intratendinous strain fields of the supraspinatus tendon: Effect of a surgically created articular-surface rotator cuff tear. J Shoulder Elbow Surg, 11:562-569, 2002 (PMID 12469080).
  42. Thomopoulos, S., Williams, G.R., and Soslowsky, L.J.: Tendon to bone healing: Differences in biomechanical, structural, and compositional properties due to a range of activity levels. J Biomech Eng, 125:106-113, 2003 (PMID 12661203).
  43. Kuhn, J.E., Lindholm, S.R., Huston, L.J., Soslowsky, L.J., and Blasier, R.B.: Failure of the biceps superior labral complex: A cadaveric biomechanical investigation comparing the late cocking and early deceleration positions of throwing. Arthroscopy, 19:373-379, 2003 (PMID 12671620).
  44. Elliott, D.M., Robinson, P.S., Gimbel, J.A., Sarver, J.J, Abboud, J.A., Iozzo, R.V., and Soslowsky, L.J.: Effect of altered matrix proteins on quasilinear viscoelastic properties in transgenic mouse tail tendons. Annals Biomed Eng, 31:599-605, 2003 (PMID 12757203).
  45. Thomopoulos, S., Williams, G.R., Gimbel, J.A., Favata, M., and Soslowsky, L.J.: Variation of biomechanical, structural and compositional properties along the tendon to bone insertion site. J Orthop Res, 21:413-419, 2003 (PMID 12706013).
  46. Mehta, S.M., Gimbel, J.A., and Soslowsky, L.J.: Etiologic and pathogenetic factors for rotator cuff tendinopathy. Clin Sports Med, 22:791-812, 2003 (PMID 14560548).
  47. Beredjiklian, P.K., Favata, M., Cartmell, J.S., Flanagan, C.L., Crombleholme, T.M., and Soslowsky, L.J.: Regenerative vs. reparative healing in tendon: A study of biomechanical and histological properties in fetal sheep. Annals Biomed Eng, 31:1143-1152, 2003 (PMID 14649488).
  48. Robinson, P.S., Placide, R., Soslowsky, L.J., and Born, C.T.: Mechanical strength of repairs of the hips short external rotators. J Arthroplasty, 19:204-210, 2004 (PMID 14973864).
  49. Huang, T.F., Perry, S.M., and Soslowsky, L.J.: Achilles vs supraspinatus tendon changes due to treadmill running in an animal model. Annals Biomed Eng, 32:336-341, 2004 (PMID 15095808).
  50. Gimbel, J.A., Van Kleunen, J.P., Mehta, S., Perry, S.M., Williams, G.R., and Soslowsky, L.J.: Supraspinatus tendon structural and mechanical properties in a chronic rotator cuff tear animal model. J Biomechanics, 37:739-749, 2004 (PMID 15047003).
  51. Lin, T.W., Cardenas, L, and Soslowsky, L.J.: Biomechanics of tendon injury and repair. J Biomechanics, 37:865-877, 2004 (PMID 15111074).
  52. Robinson, P.S., Lin, T.W., Reynolds, P., Derwin, K., Iozzo, R., and Soslowsky, L.J.: Strain rate sensitive mechanical properties of tendon fascicles from mice with genetically engineered alterations in collagen and decorin. J Biomech Eng, 126:252-257, 2004 (PMID 15179856).
  53. Robinson, P.S., Lin, T.W., Reynolds, P., Jawad, A., Iozzo, R., and Soslowsky, L.J.: Investigating tendon fascicle structure-function relationships in a transgenic-age mouse model using multiple regression models. Annals Biomed Eng, 32:924-931, 2004 (PMID 15298430).
  54. Gimbel, J.A., Mehta, S., Van Kleunen, J.P., Williams, G. R., and Soslowsky, L.J.: The tension required at repair to re-appose the supraspinatus tendon to bone rapidly increases following injury. Clin Orth Rel Res, 426:258-265, 2004 (PMID 15346083).
  55. Gimbel, J.A., Sarver, J.J., and Soslowsky, L.J.: The effect of overshoot on estimating viscoelastic properties from stress relaxation experiments. J Biomech Eng, 126:844-848, 2004 (PMID 15796344).
  56. Lin, T.W., Cardenas, L, and Soslowsky, L.J.: Tendon properties in interleukin-4 and interleukin-6 knockout mice. J Biomechanics, 38:99-105, 2005 (PMID 15519344).
  57. Perry, S.M., Hoffman, M.C., and Soslowsky, L.J.: Inflammatory and angiogenic mRNA levels are altered in a supraspinatus tendon overuse animal model. J Shoulder Elbow Surg, 14:S79-83, 2005 (PMID 15726091).
  58. Barton, E.R., Gimbel, J.A., Perry, S.M., Young, S.D. III, Williams, G.R., and Soslowsky, L.J.: Rat supraspinatus muscle atrophy after tendon detachment. J Orthop Res, 23:259-265, 2005 (PMID 15734235).
  59. Yokota, A., Gimbel, J.A., Williams, G.R and Soslowsky, L.J.: Supraspinatus tendon composition remains altered long after tendon detachment. J Shoulder Elbow Surg, 14:S72-78, 2005 (PMID 15726090).
  60. Kuhn, J.E., Huston, L.J., Soslowsky, L.J., Shyr, Y., and Blasier, R.B.: Ligament restraints and muscle effects in the neutral and abducted positions. J Shoulder Elbow Surg, 14:S39-48, 2005 (PMID 15726086).
  61. Zhang, G., Young, B.B., Ezura, Y., Favata, M., Soslowsky, L.J., Chakravarti, S., and Birk, D.E.: Development of tendon structure and function: Regulation of collagen fibrillogenesis. J Musculoskeletal Neuronal Interactions, 5:5-21, 2005 (PMID 15788867).
  62. Robinson, P.S., Huang, T.F., Kazam, E., Iozzo, R.V., Birk, D.E., and Soslowsky, L.J.: Influence of decorin and biglycan on mechanical properties of multiple tendons in knockout mice. J Biomech Eng, 127:181-185, 2005 (PMID 15868800).
  63. Lin, T.W., Cardenas, L, Glaser, D.L., and Soslowsky, L.J.: Tendon healing in interleukin-4 and interleukin-6 knockout mice. J Biomechanics, 39:61-69, 2006 (PMID 16271588).
  64. Zhang, G., Ezura, Y., Chervoneva, I., Robinson, P.S., Beason, D.P., Carine, E.T., Soslowsky, L.J., Iozzo, R.V., and Birk, D.E.: Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development. J Cell Biochem, 98:1436-1449, 2006 (PMID 16518859).
  65. Favata, M., Beredjiklian, P.K., Zgonis, M.H., Beason, D.P., Crombleholme, T.M., Jawad, A.F., and Soslowsky, L.J.: Regenerative properties of fetal sheep tendon are not adversely affected by transplantation into an adult environment. J Orthop Res, 24:2124-2132, 2006 (PMID 16944473).
  66. Ticker, J.B., Flatow, E.L., Pawluk, R.J., Soslowsky, L.J., Arnoczky, S.P., Hepler, M.D., Bigliani, L.U., and Mow, V.C.: The inferior glenohumeral ligament: A correlative biomechanical, biochemical, and histological investigation. J Shoulder Elbow Surg, 15:665-674, 2006 (PMID 16963285).
  67. Christner, P.J., Gentiletii, J., Peters, J., Ball, S.T., Yamauchi, M., Atsawasuwan, P., Beason, D.P., Soslowsky, L.J., and Birk, D.E.: Collagen dysregulation in dermis of the SAGG/+ mouse: A loose skin model, J Invest Derm, 126:595-602, 2006 (PMID 16424879).
  68. Gimbel, J.A., Van Kleunen, J.P., Lake, S.P., Williams, G.R., and Soslowsky, L.J.: The role of repair tension on tendon to bone healing in an animal model of chronic rotator cuff tears. J Biomech, 40:561-568, 2007 (PMID 16600252).
  69. Archambault, J.M., Jelinsky, S.A., Lake, S.P., Hill, A.A., Glaser, D.L. and Soslowsky, L.J.: Rat supraspinatus tendon expresses cartilage markers with overuse, J Orthop Res, 25:617-624, 2007 (PMID 17318892).
  70. Gimbel, J.A., Van Kleunen, J.P., Williams, G.R., Thomopoulos, S., and Soslowsky, L.J.: Long durations of immobilization may be necessary to enhance the mechanical properties of the healing supraspinatus tendon. J Biomech Eng, 129:400-404, 2007 (PMID 17536907).
  71. Perry, S.M., Van Kleunen, J.P., Ramsey, M.L., and Soslowsky, L.J. and Glaser, D.L.: Use of small intestine submucosa in an acute and chronic rotator cuff tear rat model. J Shoulder Elbow Surg, 16:179S-183S, 2007 (PMID 17629508).
  72. Wuergler-Hauri, C.C., Dourte, L.M., Baradet, T.C., Williams, G.R., and Soslowsky, L.J.: Temporal expression of eight growth factors in tendon to bone healing in a rat supraspinatus model. J Shoulder Elbow Surg, 16:198S-203S, 2007 (PMID 17903711).
  73. Sarver, J.J., Peltz, C.D., Dourte, L., Reddy, S., Williams, G.R., and Soslowsky, L.J.: After rotator cuff repair, stiffness--but not the loss in range of motion--increased transiently for immobilized shoulders in a rat model. J Shoulder Elbow, Surg, 17:108S-113S, 2008 (PMID 18201650).
  74. Gordon, A., Kozin, E.D., Keswani, S.G., Vaikunth, S.S., Katz, A.B., Zoltick, P.W., Favata, M., Radu, A.P., Soslowsky, L.J., Herlyn, M., Crombleholme, T.M.: Permissive environment in postnatal wounds induced by adenoviral-mediated overexpression of the anti-inflammatory cytokine interleukin-10 prevents scar formation. Wound Repair and Regen, 16:70-79 2008 (PMID 18086289).
  75. Jelinsky, S.A., Lake, S.P., Archambault, J.M., and Soslowsky, L.J.: Gene expression in rat supraspinatus tendon recovers from overuse with rest. Clin Orthop Rel Res, 466:1612-1617, 2008 (PMCID 2505258).
  76. Ricchetti, E.T., Reddy, S.C., Ansorge, H.L., Zgonis, M.H., van Kleunen, J.P., Liechty, K.W., Soslowsky, L.J., Beredjiklian, P.K.: The effect of interleukin-10 (IL-10) overexpression on the properties of healing tendon. J Hand Surg (Am), 33:1843-1852, 2008.
  77. Perry, S.M., Getz, C.L., Soslowsky, L.J.: After rotator cuff tears, the remaining (intact) tendons are mechanically altered. J Shoulder Elbow Surg, 18:52-57, 2009 (PMCID 2745652).
  78. Andarawis-Puri, N., Ricchetti, E.T., and Soslowsky, L.J.: Rotator cuff tendon strain correlates with tear propagation. J Biomechanics, 42:158-163, 2009 (PMCID 2775924).
  79. Peltz, C.D, Perry, S.M., Getz, C.L., Soslowsky, L.J.: Mechanical properties of the long-head of the biceps tendon are altered in the presence of rotator cuff tears in a rat model. J Orthop Res, 27:416-420, 2009 (PMCID 2819372).
  80. Perry, S.M., Getz, C.L., and Soslowsky, L.J.: Alterations in function after rotator cuff tears in an animal model. J Shoulder Elbow Surg, 18:296-304, 2009 (PMCID 2669656).
  81. Ansorge, H.L., Meng, X., Zhang, G., Veit, G., Sun, M., Klement, J.F., Beason, D.P., Soslowsky, L.J., Koch, M., and Birk, D.E.: Type XIV collagen regulates fibrillogenesis: premature collagen fibril growth and tissue dysfunction in null mice. J Biol Chem, 284:8427-8438, 2009 (PMCID 2659201).
  82. Gilley, R.S., Beason, D.P., Snyder, D.M., Boston, R.C., Radin, A., Kapatkin, A.S., Smith, G.K., and Soslowsky, L.J.: External fixator clamp reuse degrades clamp mechanical performance. Vet Surg, 38:530-536, 2009 (PMCID 2659201).
  83. Andarawis-Puri, N.A., Ricchetti, E.T., and Soslowsky, L.J.: Interaction between the supraspinatus and infraspinatus tendons: effect of anterior supraspinatus tendon full thickness tears on infraspinatus tendon strain. Am J Sports Med, 37:1831-1839, 2009 (PMCID 2746054).
  84. Ansorge, H.L., Beredjiklian, P.K., and Soslowsky, L.J.: CD44 Deficiency improves healing tendon mechanics and increases matrix and cytokine expression in a mouse patellar tendon injury model. J Orthop Res, 27:1386-1391, 2009 (PMCID 2810854).
  85. Peltz, C.D., Dourte, L.M., Kuntz, A.F., Sarver, J.J., Williams, G.R., Soslowsky, L.J.: The effect of post-operative passive motion on rotator cuff healing in a rat model. J Bone Joint Surg, 91:2421-2429, 2009 (PMCID 2752309).
  86. Lake, S.P., Miller, K.S., Elliott, D.M., and Soslowsky, L.J.: Effect of fiber distribution and realignment on the nonlinear and inhomogeneous mechanical properties of human supraspinatus tendon under longitudinal tensile loading. J Orthop Res, 27:1596-1602, 2009 (PMCID 2813200).
  87. Malicky, D.M. and Soslowsky, L.J.: Relationships between total and non-recoverable strain fields in glenohumeral capsule during shoulder subluxation. Ann Biomed Eng, 37:2547-2555, 2009.
  88. Butler, D.L., Goldstein, S.A., Guldberg, R.E., Guo, X.E., Kamm, R., Laurencin, C.T., McIntire, L.V., Mow, V.C., Nerem, R.M., Sah, R.L., Soslowsky, L.J., Spilker, R.L., Tranquillo, R.: The impact of biomechanics on tissue engineering and regenerative medicine. Tissue Eng, Part B, 15:477-484, 2009.
  89. Andarawis-Puri, N.A., Kuntz, A.F., Kim, S-Y., and Soslowsky, L.J.: Effect of anterior supraspinatus tendon partial-thickness tears on infraspinatus tendon strain through a range of joint rotation angles. J Shoulder Elbow Surg, 19:617-621, 2010 (PMCID 2872028).
  90. Lake, S.P., Miller, K.S., Elliott, D.M., and Soslowsky, L.J.: Tensile properties and fiber alignment of human supraspinatus tendon in the transverse direction demonstrate inhomogeneity, nonlinearity and regional isotropy, J Biomech, 43:727-732, 2010 (PMCID 2823853).
  91. Sarver, J.J., Dishowitz, M.I., Kim, S.Y., and Soslowsky, L.J.: Transient decreases in forelimb gait and ground reaction forces following rotator cuff injury and repair in a rat model. J Biomech, 43:778-782, 2010 (PMCID 2823944).
  92. Peltz, C.D., Sarver, J.J., Dourte, L.M., Wuergler-Hauri, C.C., Williams, G.R., and Soslowsky, L.J.: Exercise following a short immobilization period is detrimental to tendon properties and joint mechanics in a rat rotator cuff injury model. J Orthop Res, 28:841-845, 2010 (PMCID 2902767).
  93. Andarawis-Puri, N., Kuntz, A.F., Ramsey, M.L., and Soslowsky, L.J.: Effect of glenohumeral abduction angle on the mechanical interaction between the supraspinatus and infraspinatus tendons for the intact, partial-thickness torn and repaired supraspinatus tendon conditions. J Orthop Res, 28:846-851, 2010.
  94. Dourte, L.M., Perry, S.M., Getz, C.L. and Soslowsky, L.J.: Tendon properties remain altered in a chronic rat rotator cuff model. Clin Orthop Rel Res, 468:1485-1492, 2010 (PMCID 2865621).
  95. Andarawis-Puri, N., Kuntz, A.F., Jawad, A.F., and Soslowsky, L.J.: Infraspinatus and supraspinatus tendon strain explained using multiple regression models. Ann Biomed Eng, 38:2979-2987, 2010 (PMCID 20458629).
  96. Cortes, D.H., Lake, S.P., Kadlowec, J.A., Soslowsky, L.J. and Elliott, D.M.: Characterizing the mechanical contribution of fiber angular distribution in connective tissue: comparison of two modeling approaches. Biomechanics Modeling Mechanobiology, in press, 2010 (PMCID 2917498).
  97. Herdrich BJ, Danzer E, Davey M, Bermudez DM, Radu A, Zhang L, Zhang Z, Soslowsky LJ, Liechty KW. Fetal tendon wound size modulates wound gene expression and subsequent wound phenotype. Wound Repair Regen 18:543-549, 2010 (PMCID 2941238).
  98. Ward, S.R., Sarver, J.J., Eng, C.M., Kwan, A., Wurgler-Hauri, C.C., Perry, S.M., Williams, G.R., Soslowsky, L.J., and Lieber, R.L., Plasticity of muscle architecture after acute supraspinatus tear. J Orthop Sports Phys Therapy, in press, 2010.
  99. Peltz, C.D., Hsu, J.E., Zgonis, M.H., Trasolini, N.A., Glaser, D.L., and Soslowsky, L.J.: The effect of altered loading following rotator cuff tears in a rat model on the regional mechanical properties of the long head of the biceps tendon, J Biomechanics, 43:2904-2907, 2010 (PMCID 2975832).
  100. Beason, D.P., Abboud, J.A., Kuntz, A.F., Bassora, R., Soslowsky, L.J.: Cumulative Effects of Hypercholesterolemia on Tendon Biomechanics in a Mouse Model, J Orthop Res, 29:380-383, 2011.
  101. Izu, Y., Ansorge, H.L., Zhang, G., Soslowsky, L.J., Bonaldo, P., Chu, M.L., Birk, D.E.: Dysfunctional tendon collagen fibrillogenesis in collagen VI null mice, Matrix Biology, 30:53-61, 2011.
  102. Peltz, C.D., Hsu, J.E., Zgonis, M.H., Trasolini, N.A., Glaser, D.L., Soslowsky, L.J.: Biceps tendon properties worsen initially but improve over time following rotator cuff tears in a rat model, J Orthop Res, 29:874-879, 2011.
  103. Abboud, J., Beason, D.B., Soslowsky, L.J.: The effect of hypercholesterolemia on tendons, Clin Orthop Rel Rel, in press, 2011.
  104. Andarawis-Puri N, Kuntz AF, Ramsey ML, Soslowsky LJ. Effect of supraspinatus tendon repair technique on the infraspinatus tendon. J Biomech Eng, in press, 2011.
  105. Peltz, C.D., Hsu, J.E., Zgonis, M.H., Trasolini, N.A., Glaser, D.L., Soslowsky, L.J.: Decreased loading following rotator cuff tears leads to improved biceps tendon properties in a rat model. J Shoulder Elbow Surg, in press, 2011 (NIHMS 258225).
  106. Hsu, J.E., Reuther, K.E., Sarver, J.J., Lee, C.S., Thomas, S.J., Glaser, D.L., Soslowsky, L.J.: Restoration of anterior-posterior rotator cuff force balance improves shoulder function in a rat model of chronic massive tears. J Orthop Res, 29:1028-1033, 2011(PMCID 21308755).
  107. Bermudez, D.M., Herdrich, B.J., Xu, J., Lind, R., Beason, D.P., Mitchell, M.E., Soslowsky, L.J., Liechty, K.W.: Impaired biomechanical properties of diabetic skin: Implications in the pathogenesis of diabetic wound complications, Am J Pathol, in press, 2011 (PMCID 3081147).
  108. Ansorge, H.L., Adams, S., Birk, D.E., Soslowsky, L.J.: Mechanical, Compositional and structural properties of the post-natal mouse Achilles tendon, Ann Biomed Eng, 39:1904-1911, 2011.
  109. Lake, S.P., Cortes, D.H., Kadlowec, J.A., Soslowsky, L.J., and Elliott, D.M.: Evaluation of affine fiber kinematics in human supraspinatus tendon using quantitative projection plot analysis, Biomech Modeling Mechanobiology, in press, 2011.
  110. Wenstrup, R.J., Smith, S.M., Florer, J.B., Zhang, G., Beason, D.P., Seegmill,er R.E. Sosowsky, L.J., and Birk, D.E.: Regulation of collagen fibril nucleation and initial fibril assembly involves coordinate interactions with collagens V and XI in developing tendon, J Biol Chem, 286:20455-20465, 2011.
  111. Peltz, C., Hsu, J.E., Zgonis, M.H., Trasolini, N.A., Glaser, D.L., and Soslowsky, L.J.: Intra-articular changes precede extra-articular changes in the biceps tendon following rotator cuff tears in a rat model, J Shoulder Elbow Surg, in press, 2011 (NIHMS 296289).
  112. Castello-Cros, R., Whitaker-Menezes, D., Molchansky, A. , Purkins, G., Soslowsky, L.J., Beason, D.P., Sotgia, F., Iozzo, R.V., and Lisanti, M.P.: Scleroderma-like properties of skin from caveolin-1 deficient mice: Implications for new treatment strategies in patients with fibrosis and systemic sclerosis, Cell Cycle, in press, 2011.
  113. Attia, M., Scott, A., Soslowsky, L.J., Duchesnay, A., van Kuppevelt, T., Carpenter, G., Papy-Garcia, D., Courty, J., Tassoni, M-C., and Martelly, I.: Alterations of overused supraspinatus tendon: a possible role of glycosaminoglycans and HARP/Pleiotrophin in early tendon pathology, J Orthop Res, in press, 2011.


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