Ashwin S. Nathan
Undergraduate Student in Bioengineering
University of Pennsylvania
Hometown
Bryn Mawr, Pennsylvania
Education
BSE Bioengineering, 2009, University of Pennsylvania
Areas of Special Interest
Ashwin joined the lab in the summer of '06 and is currently working on developing a tissue engineered construct that emulates the properties of the native meniscus. Having worked on various projects, he has narrowed his focus to the response of mesenchymal stem cells to static strain. An avid Philadelphia sports fan, he hopes to take on, as a side project, the mending of broken hearts.
Publications
Baker BM, Gee AO, Metter RB, Nathan AS, Marklein RA, Burdick JA, Mauck RL. "Selective Removal of Sacrificial Fibers Improves Cell Infiltration in Composite Fiber-Aligned Nanofibrous Scaffolds," Biomaterials, in press.
Baker BM, Nathan AS, Huffman GR, Mauck RL. "Tissue Engineering of Meniscus Constructs with Autologous Human Fibrochondrocytes Derived from Surgical Debris," Osteoarthritis and Cartilage, in review.
Conference Abstracts
Sheth NP, Baker BM, Nathan AS, Mauck RL: "Biologic Integration of Fiber-Aligned Nanofibrous Scaffolds with Native Meniscus" 53rd Annual Meeting of the Orthopaedic Research Society, San Diego, CA, February 11-14, 2007 (submitted).
Baker BM, Tan AR, Metter RB, Nathan AS, Mauck RL: "Nanofiber Alignment Enhances the Development of Engineered Meniscus Constructs" 53rd Annual Meeting of the Orthopaedic Research Society, San Diego, CA, February 11-14, 2007 (submitted).
Baker BM, Nathan AS, Sheth NP, Huffman GR, Mauck RL. "Autologous Human Fibrochondrocytes from Meniscectomy Debris are a Potent Cell Source for Meniscus Tissue Engineering," Proceedings of ASME 2007 Summer Bioengineering Conference, Keystone, CO, June 20-24, poster.
Baker BM, O'Connell GD, Sen S, Nathan AS, Elliott DM, Mauck RL. "Multi-Lamellar and Multi-Axial Maturation of Cell-Seeded Fiber-Reinforced Tissue Engineered Constructs," Proceedings of ASME 2007 Summer Bioengineering Conference, Keystone, CO, June 20-24, podium.
Baker BM, Nathan AS, Mauck RL. "Tensile Loading Modulates Collagen Gene Expression in MSC-Laden Nanofibrous Scaffolds," 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, March 2-5, 2008, submitted.
Baker BM, Gee AO, Jennings MW, Nathan AS, Huffman GR, Mauck RL. "Engineering Anatomically-Shaped Meniscus Constructs: Biologic and Mechanical Integration," 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, March 2-5, 2008, submitted.
Baker BM, Nathan AS, Huffman GR, Mauck RL. "Structure-Function Correlations of Young and Aged Human Fibrochondrocyte-Seeded Engineered Meniscus Constructs," 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, March 2-5, 2008, submitted.
Baker BM, Gee AO, Marklein RA, Nathan AS, Burdick JA, Mauck RL. "Tuning Nanofibrous Scaffold Mechanics and Porosity to Promote Cell Infiltration," 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, March 2-5, 2008, submitted.