Graduate Student in Cell and Molecular Biology
University of Pennsylvania
Hometown: York, Pennsylvania
Education: B.S. Chemistry, 2008, West Chester University of Pennsylvania
Areas of Special Interest: Stem cell differentiation, BMP receptor signaling, Cartilage formation
Chakkalakal SA, Zhang D, Culbert AL, Convente MR, Caron RJ, Wright AC, Maidment ADA, Kaplan FS, Shore EM. An Acvr1 knock-in mouse has fibrodysplasia ossificans progressiva. Journal of Bone and Mineral Research 27(8): 1746-1756, 2012.
Culbert AL, Chakkalakal SA, Convente MC, Lounev VY, Kaplan FS, Shore EM. 2013, Genetics of Bone Biology and Skeletal Disease, Chapter 24: Fibrodysplasia (myositis) ossificans progressiva, Elsevier, San Diego, CA.
Conference Papers and Abstracts:
Culbert AL, Chakkalakal SA, Caron RJ, Shore EM. Gain-of-function Alk2 mutation enhances chondrocyte differentiation and promotes heterotopic endochondral ossification. Gordon Research Conference: Cartilage Biology and Pathology, Les Diablerets, Switzerland, 2013. (accepted)
Culbert AL, Chakkalakal SA, Caron RJ, Shore EM. The FOP R206H Alk2 Mutation Enhances BMP-Induced Chondrogenic Differentiation. American Society of Bone and Mineral Research Annual Meeting, Minneapolis, Minnesota, Abstract No. FR0091, 2012. (poster presentation)
Chakkalakal SA, Culbert AL, Convente MR, Zhang D, Kaplan FS, Shore EM. The Alk2 R206H (FOP) mutation causes lower limb chondrodysplasia in mice. American Society of Bone and Mineral Research Annual Meeting, San Diego, California, Abstract No. SU0095, 2011. (poster presentation)
Culbert AL, Chakkalakal SA, Shore EM. The Alk2 R206H (FOP) mutation enhances sensitivity to chondrogenic differentiation. Fifth Fellows Forum on Metabolic Bone Diseases, San Diego, California, Abstract No. 36, 2011. (poster presentation)
Culbert AL, Shore EM. The effect of the FOP ACVR1 R206H mutation on chondrogenic differentiation. Penn Center for Musculoskeletal Disorders Annual Symposium, Philadelphia, Pennsylvania, Abstract No. P35, 2011. (poster presentation)
GAPSA President's Award Travel Grant, 2013
ASBMR Young Investigator Travel Grant, 2012
EFF-ASBMR Fellow, 2011