Perelman School of Medicine at the University of Pennsylvania

McKay Orthopaedic Research Laboratory

Soslowsky Laboratory

Julianne Huegel, Ph.D.

Julianne Huegel

Postdoctoral Fellow
University of Pennsylvania

Hometown: Gainesville, Florida

 


Education:
Ph.D. Cell and Developmental Biology, 2013, Thomas Jefferson University
B.S.E. Bioengineering, 2008, University of Pennsylvania

Publications:
Huegel J
, Sgariglia F, Enomoto-Iwamoto M, Koyama E, Pacifici M. Heparanase modulates chondrogenic response and is upregulated in ectopic cartilage. In preparation.

Sgariglia F, Candela ME, Huegel J, Jacenko O, Koyama E, Yamaguchi Y, Pacifici M, Enomoto-Iwamoto M. 2013. Epiphyseal abnormalities, trabecular bone loss and articular chondrocyte hypertrophy develop in the long bones of postnatal Ext1-deficient mice. Bone 57: 220-231.

Huegel J, Sgariglia F, Enomoto-Iwomoto M, Koyama E, Dormans JP, Pacifici M. 2013. Heparan Sulfate in Skeletal Development, Growth, and Pathology: The Case of Hereditary Multiple Exostoses. Dev Dyn 242: 1021-1032.

Huegel J, Mundy C, Sgariglia F, Nygren P, Billings PC, Yamaguchi Y, Koyama E, Pacifici M. 2013. Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: A mechanism likely deranged in Hereditary Multiple Exostoses. Dev Biol 377:110-112.

Conference Abstracts:
Huegel, J., (2012, November). Homeostasis and Degradation of Heparan Sulfate: Involvement in Normal and Pathological Skeletogenesis. Abstract for poster presentation. American Society for Matrix Biology, San Diego, CA.

Huegel, J., (2012, November). Homeostasis and Degradation of Heparan Sulfate: Involvement in Normal and Pathological Skeletogenesis. Abstract for podium presentation. Fourth International Research Conference on Multiple Hereditary Exostoses, Philadelphia, PA November 2012.

Huegel, J., (2012, February). Heparan Sulfate Dependent Mechanisms of Pathological Skeletogenesis. Abstract for poster presentation. Orthopaedic Research Society, San Francisco, CA.

Huegel, J., (2011, June). Mechanisms of Exostosis Formation in HME Syndrome. Abstract for podium presentation. Bones & Teeth Gordon Research Seminar, Les Diablerets, Switzerland.

Huegel, J., (2011, January). Mechanisms of Exostosis Formation In a Mouse Model of Hereditary Multiple Exostoses. Abstract for podium presentation, Orthopaedic Research Society, Long Beach, CA.

Huegel, J., (2010, October). Pathogenesis of Hereditary Multiple Exostoses: Modeling Exostosis Formation In Vivo and In Vitro. Abstract for poster presentation, American Society for Matrix Biology, Charleston, SC.

Huegel, J., (2010, October). Mechanisms of Exostosis Formation in Hereditary Multiple Exostoses Syndrome. Abstract for podium presentation, American Society for Bone and Mineral Research, Toronto, ON.

 

Julianne joined the McKay Orthopaedic Research Laboratory in 2014. She enjoys running, reading, traveling, and cooking/eating/writing about food.