Welcome to Soslowsky Laboratory
The overall goals of our research program are to determine fundamental relationships and mechanisms of tendon and ligament injury, healing, repair, and regeneration and to use this information to develop and evaluate potential treatment modalities.
Our primary research areas include:
- Rotator cuff injury and repair
- The Role of NSAIDs on Tendon Healing
- Achilles Tendon Injury and Repair
- Scarless regenerative tendon healing
- Tendon structure-function relationships and injury-repair
- Congratulations to Sarah I. Rooney for receiving the 2015 Savio L-Y Woo Young Researcher Award, which will be presented to her at the International Symposium of Ligaments & Tendons XIV in Las Vegas, Nevada!
- Congratulations to Ben Freedman for coming in 2nd place in the 2015 BE Symposium poster session for his poster titled, "Novel application of a micro-CT perfusion technique to evaluate Achilles tendon vessel microarchitecture in three dimensions!"
Congratulations to Julianne Potocek and Alexis Williams for their new review paper, "Rotator cuff biology and biomechanics: a review of normal and pathological conditions" published in Curr Rheumatol Rep!
Congratulations to Mike and Alex Hast for the birth of their son, Lucas Michael Hast!
Congratulations to Bri Connizzo and J Sarver for their new paper, "In situ fibril stretch and sliding is location-dependent in mouse supraspinatus tendons" published in the Journal of Biomechanics!
- Congratulations go out to Cori Riggin, J. Sarver, Ben Freedman, Steve Thomas, and Lou Soslowsky. Their paper, entitled "Analysis of Collagen Organization in Mouse Achilles Tendon Using High-Frequency Ultrasound Imaging" was chosen as one of the 2014 Editors' Choice papers for the Journal of Biomechanical Engineering!
Congratulations to Pankti and Ruchir Bhatt for the birth of their daughter, Arya Ruchir Bhatt!
Congratulations to Mike Hast for his new review paper, "Exploring the role of hypercholesterolemia in tendon health and repair" published in Muscle Ligaments Tendons Journal!
- Happy Halloween from a few of the lab rats in our group!
- Congratulations to Ben Freedman, Cori Riggin, Adam Pardes, Bri Connizzo, and Sarah Rooney, whose outreach efforts, as part of Penn's Graduate Association of Bioengineering and Chapter of Biomedical Engineering Society, are featured in a recent copy of the Daily Pennsylvanian!
- Congratulations to Katie Reuther for her paper entitled "Scapular dyskinesis is detrimental to shoulder tendon properties and joint mechanics in the rat model" published in the Journal of Orthopaedic Research.
- The group received a 2nd percentile score for an R01 grant submission entitled "Mouse Models for SLRP Roles in Tendon Aging and Imapaired Healing in Aging Tendons"!
- Lou Soslowsky acted as an Ad Hoc Study Section Member for the National Institutes of Health/NIAMS, Special Emphasis Panel (K, T32).
- Lou Soslowsky co-chaired the New Frontiers in Tendon Research sponsored by ORS, NIH/NIAMS, and ISSM. He also gave a Keynote talk at that conference entitled "Current State of the Tendon Field." He will serve as Co-Guest Editor for an issue of the Journal of Orthopaedic Research on the same topic.
- Funding for the R01 grant entitled "Injury Response in Normal and EDS Tendons: Regulatory Roles of Collagen V" began on July 1st.
- Congratulations to Ben Freedman, Cori Riggin, Adam Pardes, Bri Connizzo, Sarah Rooney, and Katie Reuther for their efforts on the eboard for UPenn's Graduate Association of Bioengineering (GABE) and student chapter of the Biomedical Engineering Society (BMES). The chapter was awarded the Outstanding Outreach Award from the National BMES! As part of the award, a plaque will be presented to the chapter at the national BMES conference in October. In addition, Ben Freedman and Kush Mehta (Mauck Lab) will be in attendance to present at a session on outreach and mentoring activities.
- Congratulations to Ben Freedman for coming in 2nd place in the Tissue and Cellular Engineering category of the MS poster competition at the World Congress of Biomechanics for his poster titled: "Novel application of a micro-CT perfusion technique to evaluate Achilles tendon vessel microarchitecture in three dimensions.
- Congratulations to Dr. Katie Reuther for successfully defending her thesis! Good luck in your future endeavors in professorship at Columbia University!
- Lou Soslowsky presented two lectures in Switzerland: "How Hypercholesterolemia Modifies Tendons" (Lugano) and "Tendon Healing in a Rotator Cuff Animal Model" (Zurich).
- Congratulations to Cori Riggin for her paper titled "Intra-articular tibiofemoral injection of a nonsteroidal anti-inflammatory drug has no detrimental effects on joint mechanics in a rat model." published in the Journal of Orthopaedic Research!
- Congratulations to Michael Hast for his paper titled "The role of animal models in tendon research" published in Bone and Joint Research!
- Congratulations to Bri Connizzo for her paper titled "Diabetes Alters Mechanical Properties and Collagen Fiber Re-Alignment in Multiple Mouse Tendons" published in Annals of BME!