Perelman School of Medicine at the University of Pennsylvania

McKay Orthopaedic Research Laboratory

Soslowsky Laboratory

Ongoing Research Projects

Rotator Cuff Injury and Repair

Rotator cuff disease is the most common cause of shoulder pain and dysfunction in adults. Common injuries to the rotator cuff include tendon tears (from a traumatic event) or overuse tendon injuries (from repetitive motion or loading). Utilizing cadaveric shoulders and animal models of tendon injury, our laboratory uses biomechanical, histological, organizational and biological assays, as well as medical imaging techniques, to study rotator cuff injury and repair. In addition, current projects aim to evaluate shoulder healing when tendon is repaired with the aid of a biologic or synthetic graft. Specific, ongoing research in this area includes the following:

Animal Models of Tendon Injury and Repair

  1. Rotator Cuff Tendon to Bone Insertion Site Healing
  2. The Role of Altered Loading in Pathological Changes in the Long Head of the Biceps Tendon Following Rotator Cuff Tear
  3. Multi-Tendon Chronic Model
  4. Joint Damage

Non-invasive Rotator Cuff Tendon Evaluation

  1. DQF-NMR
  2. Ultrasound