Ostap Laboratory

Selected Recent Publications

For a complete list of Ostap Laboratory publications from PubMed, click here.

McIntosh BB, Holzbaur, ELF, Ostap EM.
Control of the initiation and termination of kinesin-1 driven transport by myosin-Ic and nonmuscle tropomyosin.
Curr Biol. 2015;25(4):523-9. Link.

Greenberg MJ, Shuman H, Ostap EM.
Inherent force-dependent properties of ß-cardiac myosin contribute to the force-velocity relationship of cardiac muscle.
Biophys J. 2014;107(12):L41-4. Link.

Shuman H, Greenberg MJ, Zwolak A, Lin T, Sindelar CV, Dominguez R, Ostap EM.
A vertebrate myosin-I structure reveals unique insights into myosin mechanochemical tuning.
Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2116-21. Epub 2014 Jan 27. Link.

Ayloo S, Lazarus JE, Dodda A, Tokito M, Ostap EM, Holzbaur EL
Dynactin functions as both a dynamic tether and brake during dynein-driven motility.
Nat Commun. 2014;5:4807. Link.

Zwolak A, Yang C, Feeser EA, Ostap EM, Svitkina T, Dominguez R.
CARMIL leading edge localization depends on a non-canonical PH domain and dimerization.
Nat Commun. 2013;4:2523. Link.

Pyrpassopoulos S, Shuman H, Ostap EM.
Method for measuring single-molecule adhesion forces and attachment lifetimes of protein-membrane interactions.
Methods Mol Biol. 2013;1046:389-403. Link.

Zajac AL, Goldman YE, Holzbaur EL, Ostap EM.
Local cytoskeletal and organelle  interactions impact molecular-motor- driven early endosomal trafficking. Curr Biol. 2013 Jul 8;23(13):1173-80. Epub 2013 Jun 13. Link.

Greenberg MJ, Ostap EM.
Regulation and control of myosin-I by the motor and light chain-binding domains.
Trends Cell Biol. 2013 Feb;23(2):81-9. Epub 2012 Nov 29. Link.

Dawicki-McKenna JM, Goldman YE, Ostap EM.
Sites of glucose transporter-4 vesicle fusion with the plasma membrane correlate spatially with microtubules.
PLoS One. 2012;7(8):e43662. Epub 2012 Aug 20.  Link.

Greenberg MJ, Lin T, Goldman YE, Shuman H, Ostap EM.
Myosin IC generates power over a range of loads via a new tension-sensing mechanism.
Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):E2433-40. Epub 2012 Aug 20.  Link.

Pyrpassopoulos S, Feeser EA, Mazerik JN, Tyska MJ, Ostap EM.
Membrane-bound myo1c powers asymmetric motility of actin filaments.
Curr Biol. 2012 Sep 25;22(18):1688-92. Epub 2012 Aug 2. Link.

Lewis JH, Greenberg MJ, Laakso JM, Shuman H, Ostap EM.
Calcium regulation of myosin-I tension sensing.
Biophys J. 2012 Jun 20;102(12):2799-807. Epub 2012 Jun 19. Link.

Chen C, Greenberg MJ, Laakso JM, Ostap EM, Goldman YE, Shuman H.
Kinetic schemes for post-synchronized single molecule dynamics.
Biophys J. 2012 Mar 21;102(6):L23-5. Epub 2012 Mar 20. Link.

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