Penn Center for Musculoskeletal Disorders

Home of the PCMD

Welcome to the Penn Center for Musculoskeletal Disorders!

In the News:  Congratulations to Dr. Lou Soslowsky for being awarded the H.R. Lissner Medal from the American Society of Mechanical Engineers (ASME). For more information please visit Penn Medicine News 

Congratulations! The Penn Center for Musculoskeletal Disorders has 5 more years! For more information go to

The Penn Center for Musculoskeletal Disorders (PCMD) will continue to enhance the research productivity of, and provide critical resources and programs to, investigators to address multidisciplinary research strategies for musculoskeletal problems.  The overall goal of this Center is to promote cooperative interactions among investigators, accelerate and enrich the effectiveness and efficiency of ongoing research, foster new collaborations and new research, and ultimately, translate our research efforts into better and new therapies for musculoskeletal disorders.  The central theme of the Center will continue to be “Musculoskeletal Tissue Injury and Repair”.  This theme is broad (as it includes all musculoskeletal tissue types, such as bone, cartilage, disc, ligament, meniscus, muscle, and tendon), focused (as takes advantage of commonalities in approaches across tissue types), and clinically significant (as it fosters development of assays, procedures and knowledge in pre-clinical animal and human models of translational relevance).  It is important to note that our PCMD is not a “bone center” nor is it a “muscle center”. Rather, it is truly a “musculoskeletal center” and has emerged as the recognized home for musculoskeletal research across the Penn campus and as a technical and intellectual resource for the broader Philadelphia musculoskeletal research community.  Thus, the primary overall aims of this Center are to enhance and advance the research productivity of investigators in musculoskeletal tissue injury and repair by: 1) Providing innovation within critical resource core facilities in areas that cross disciplines, length scales, and hierarchies.  These core facilities are mCT Imaging, Biomechanics, and Histology, 2) Developing a pilot and feasibility grant program for investigators, with direct mentorship, whereby new approaches, ideas, and collaborations can be developed prior to seeking extramural funding, and 3) Developing educational and research enrichment programs spanning tissue types, research approaches, and paradigms, through which members can learn from national leaders and from each other. High quality musculoskeletal research is currently being conducted by many groups at Penn.  While many bring sophisticated approaches to bear on musculoskeletal problems, few groups have the required expertise and facilities to perform high quality and specialized assays in their own labs.  Furthermore, most investigators are not aware of approaches utilized, and results obtained, in other tissues that may have direct relevance on their research questions.  Ultimately, close cooperation, communication, and collaboration among researchers across musculoskeletal tissue types and from a wide variety of disciplines will significantly enhance the research of our members.  The Center will provide opportunities to integrate multi-disciplinary techniques to determine mechanisms for tissue function, injury, degeneration, repair, and regeneration, with the ultimate goal of advancing the diagnosis, treatment, and prevention of diseases and injuries of the musculoskeletal system. 



PCMD Visiting Professorship Seminar

Tuesday, May 8, 2018
1:30pm – 2:30pm
CRB Austrian Auditorium

Sara Wickström, M.D., Ph.D.
Associate Professor at Helsinki Institute for Life Science
University of Helsinki

Title:  “Regulation of stem cell fate through niche-derived signals and mechanical forces"

For upcoming PCMD Visiting Professorship Seminars 2017-2018 click here

Biedermann Lab for Orthopaedic Research Invited Speaker

Wednesday, May 2018
1:30pm – 2:30pm
BRB 253

Timothy Wright, Ph.D.
F.M. Kirby Chair of Orthopedic Biomechanics, Hospital for Special Surgery
Senior Scientist, Hospital for Special Surgery
Professor of Applied Biomechanics, Department of Orthopaedics,Weill Medical College of Cornell University

Title:  “Evaluating Implant Failure: The Trouble with Trunnions"

Orthopaedic Research Club

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