Intracellular Trafficking and Organelle Function
HeLa cells in which the mitochondria have been stained with mitotracker green.
Investigators at Penn are elucidating the mechanisms by which the functional attributes of the organelles of the endomembrane system are established, maintained, and regulated. A major theme of this research category is intracellular protein and lipid sorting, although other important areas of organelle cell biology, including organelle motility, ion transport, and the roles of intracellular organelles in human disease are also well represented. Interactions within the interest group are fostered through numerous collaborations, journal clubs, and combined group meetings. The cell biology community at Penn provides opportunities for focused education and training related to intracellular trafficking and organelles, and consistently produces research of high quality and impact.