Cell Biology @ Penn

Recent Publications

Abrams, CS. Kindlin ignites a new flame. Blood. 2013 Oct 2; 122(14):2297-8

Aghajanian H, Choi C, Ho VC, Gupta M, Singh MK, Epstein JA. Sema3d and Sema3e direct endothelial motility through distinct molecular signaling pathways. J Biol Chem. 2014 May 13

Ahima, RS, Lazar MA. Physiology. The health risk of obesity -- better metrics imperative. Science. 2013 Aug 23; 341(6148):856-8

Alexiou S, Rubenstein RC. Seeing is believing: imaging early lung disease in cystic fibrosis. Am J Respir Crit Care Med. 2014 Apr 15;189(8):883-5

Arsenault PR, Pei F, Lee R, Kerestes H, Percy MJ, Keith B, Simon MC, Lappin TR, Khurana TS, Lee FS. A knock-in mouse model of human PHD2 gene-associated erythrocytosis establishes a haploinsufficinecy mechanism. J Biol Chem. 2013 Nov 22;288(47):33571-84. doi: 10.1074/jbc.M113.482364. Epub 2013 Oct 11.

Babich A, Burkhardt JK. Immunol Rev. 2013 Nov;256(1):80-94

Baker BM, Trappmann B, Stapleton SC, Toro E, Chen CS. Microfluidics embedded within extracellular matrix to define vascular architectures and pattern diffusive gradients. Lab Chip. 2013 Aug 21;13(16):3246-52

Bansal S, Leu AN, Gonzalez FJ, Guengerich FP, Chowdhury AR, Anandatheerthavarada HK, Avadhani NG. Mitochondrial targeting of cytochrome P450 (CYP) 1B1 and its role in polycyclic aromatic hydrocarbon-induced mitochondrial dysfunction. J Biol Chem. 2014 Apr 4;289(14):9936-51. doi: 10.1074

Bao J, Xiao J, Mao Y, Zheng XL. Carboxyl terminus of ADAMTS13 directly inhibits platelet aggregation and ultra large von Willebrand factor string formation under flow in a free-thiol-dependent manner. Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):397-407

Beiting DP, Peixoto L, Akopyants NS, Beverley SM, Wherry EJ, Christian DA, Hunter CA, Brodsky IE, Roos DS. Differential induction of TLR3-dependent innate immune signaling by closely related parasite species. PLoS One. 2014 Feb 5;9(2):e88398

Bhattacharya S, Katlinski KV, Reichert M, Takano S, Brice A, Zhao B, Yu Q, Zheng H, Carbone CJ, Katlinskaya YV, Leu NA, McCorkell KA, Srinivasan S, Girondo M, Rui H, May MJ, Avadhani NG, Rustgi AK, Fuchs SY. Triggering ubiquination of IFNAR1 protects tissues from inflammatory injury. EMBO Mol Med. 2014 Mar;6(3):384-97

Birati EY, Kirkpatrick JN, Rame JE, Bala R, Margulies KB. Dynamic left ventricular assist device inflow obstruction. Circ Heart Fail. 2014 Jan;7(1):225-6

Cang C, Bekele B, Ren D. The voltage-gated sodium channel TPC1 confers endolysosomal excitability. Nat Chem Biol. 2014 Jun;10(6):463-9

Carbone CJ, Fuchs SY. Eliminative signaling by Janus kinases: role in the down-regulation of associated receptors. J Cell Biochem. 2013 Aug 19

Carr RM, Peralta G, Yin X, Ahima RS. Absence of perilipin 2 prevents hepatic steatosis, glucose intolerance and ceramide accumulatoin in alcohol-fed mice. PLoS One. 2014 May 15;9(5):e97118

Chatterjee S, Fisher AB. Mechanotransduction in the endothelium: Role of membrane proteins and reactive oxygen species in sensing, transduction and transmission of the signal with altered blood flow. Antioxid Redox Signal. 2013 Dec 13

Choi SY, Chacon-Heszele MF, Huang L, McKenna S, Wilson FP, Zuo X, Lipschutz JH. Cdc42 deficiency causes ciliary abnormalities and cystic kidneys. J Am Soc Nephrol. 2013 Sep;24(9):1435-50

Choi YS, Zhang Y, Xu M, Yang Y, Ito M, Peng T, Cui Z, Nagy A, Hadjantonakis AK, Lang RA, Cotsarelis G, Andl T, Morrisey EE, Millar SE. Distinct functions for Wnt/B-Catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis. Cell Stem Cell. 2013 Dec 5;13(6):720-33. doi: 10.1016/j.stem.2013.10.003.

Chopra A, Murray ME, Byfield FJ, Mendez MG, Halleluyan R, Restle DJ, Raz-Ben Aroush D, Galie PA, Pogoda K, Bucki R, Marcinkiewicz C, Prestwich GD, Zarembinski TI, Chen CS, Puré E, Kresh JY, Janmey PA. Augmentation of integrin-mediated mechanotransduction by hyaluronic acid. Biomaterials. 2014 Jan;35(1):71-82. doi: 10.1016

Coffey EE, Beckel JM, Laties AM, Mitchell CH. Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer's disease-linked presenilin 1 A246E mutation can be reversed with cAMP. Neuroscience. 2014 Mar 28;263:111-24

Combs DJ, Shin HG, Xu Y, Ramu Y, Lu Z. Tuning voltage-gated channel activity and cellular excitability with a sphingomyelinase. J Gen Physiol. 2013 Oct;142(4):367-80

Cushman-Nick M, Bonini NM, Shorter J. Hsp104 suppresses polyglutamine-induced degeneration post onset in a drosophila MJD/SCA3 model. PLoS Genet. 2013 Sep;9(9):e1003781

Delaney E, Khanna P, Tu L, Robinson JM, Deutsch C. Determinants of pore folding in potassium channel biogenesis. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4620-5

Dennery PA. Signaling function of heme oxygenase proteins. Antioxid Redox Signal. 2013 Nov 1.

Dersh D, Jones SM, Eletto D, Christianson JC, Argon Y. OS-9 facilitates turnover of non-native GRP94 marked by hyper-glycosylation. Mol Biol Cell. 2014 Jun 4. pii: mbc.E14-03-0805

Desantis ME, Sweeny EA, Snead D, Leung EH, Go MS, Gupta K, Wendler P, Shorter J. Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregation. J Biol Chem. 2013 Nov 27.

Didigu CA, Wilen CB, Wang J, Duong J, Secreto AJ, Danet-Desnoyers GA, Riley JL, Gregory PD, June CH, Holmes MC, Doms RW. Simultaenous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4+ T-cells from HIV-1 infection. Blood. 2014 Jan 2;123(1):61-9

Dingal PC, Discher DE. Combining insoluble and soluble factors to steer stem cell fate. Nat Mater. 2014 Jun;13(6):532-7

Du W, Jiang P, Mancuso A, Stonestrom A, Brewer MD, Minn AJ, Mak TW, Wu M, Yang X. TAp73 enhances the pentose phosphate pathway and supports cell proliferation. Nat Cell Biol. 2013 Aug;15(8):991-1000

Eletto D, Eletto D, Dersh D, Gidalevitz T, Argon Y. Protein disulfide isomerase A6 controls the decay of IRE1a signaling via disulfide-dependent association. Mol Cell. 2014 Feb 20;53(4):562-76

Foley AR, Quijano-Roy S, Collins J, Straub V, McCallum M, Deconinck N, Mercuri E, Pane M, D'Amico A, Bertini E, North K, Ryan MM, Richard P, Allamand V, Hicks D, Lamandé S, Hu Y, Gualandi F, Auh S, Muntoni F, Bönnemann CG. Natural history of pulmonary function in collagen VI-related myopathies. Brain. 2013 Dec;136(Pt 12):3625-33. doi: 10.1093

Foreman JS, Hark L, DeLisser HM. Case writing as a vehicle for promoting cultural competency: a retrospective, descriptive qualitative analysis. J Natl Med Assoc. 2012 Jan-Feb;104(1-2):29-37

Galie PA, Nguyen DH, Choi CK, Cohen DM, Janmey PA, Chen CS. Fluid shear stress threshold regulates angiogenic sprouting. Proc Natl Acad Sci U S A. 2014 May 19. pii: 201310842

Geiss CP, Keramisanou D, Sekulic N, Scheffer MP, Black BE, Frangakis AS. CENP-A arrays are more condensed than canonical arrays at low ionic strength. Biophys J. 2014 Feb 18;106(4):875-82

Gerhardt DM, Pajcini KV, D'altri T, Tu L, Jain R, Xu L, Chen MJ, Rentschler S, Shestova O, Wertheim GB, Tobias JW, Kluk M, Wood AW, Aster JC, Gimotty PA, Epstein JA, Speck N, Bigas A, Pear WS. The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells. Genes Dev. 2014 Mar 15;28(6):576-93

Gray CM, Remouchamps C, McCorkell KA, Solt LA, Dejardin E, Orange JS, May MJ. Noncanonical NF-kB signaling is limited by classical NF-kB activity. Sci Signal. 2014 Feb 4;7(311):ra13

Guha S, Baltazar GC, Coffey EE, Tu LA, Lim JC, Beckel JM, Patel S, Eysteinsson T, Lu W, O'Brien-Jenkins A, Laties AM, Mitchell CH. Lysosomal alkalinization, lipid oxidation, and reuced phagosome clearance triggered by activation of the P2X7 receptor. FASEB J. 2013 Aug 20

Guo JL, Lee VM. Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases. Nat Med. 2014 Feb;20(2):130-8

Guo L, Giasson BI, Glavis-Bloom A, Brewer MD, Shorter J, Gitler AD, Yang X. A cellular system that degrades misfolded proteins and protects against neurodegeneration. Mol Cell. 2014 May 28. pii: S1097-2765(14)00364-5

Gurung B, Hua X. Menin/PRMT5/hedgehog signaling: a potential target for the treatment of multiple endocrine neoplasia type 1 tumors. Epigenomics. 2013 Oct;5(5):469-7

Harada T, Swift J, Irianto J, Shin JW, Spinler KR, Athirasala A, Diegmiller R, Dingal PC, Ivanovska IL, Discher DE. Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival. J Cell Biol. 2014 Mar 3;204(5):669-82

Hess PR, Rawnsley DR, Jakus Z, Yang Y, Sweet DT, Fu J, Herzog B, Lu M, Nieswandt B, Oliver G, Makinen T, Xia L, Kahn ML. Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic esparation throughout life. J Clin Invest. 2013 Dec 2. pii: 70422. doi: 10.1172/JCI70422. 

Jager J, O'Brien WT, Manlove J, Krizman EN, Fang B, Gerhart-Hines Z, Robinson MB, Klein PS, Lazar MA. Behavioral changes and dopaminergic dysregulation in mice lacking the nuclear receptor Rev-erba. Mol Endocrinol. 2014 Apr;28(4):490-8

Jakus Z, Gleghorn JP, Enis DR, Sen A, Chia S, Liu X, Rawnsley DR, Yang Y, Hess PR, Zou Z, Yang J, Guttentag SH, Nelson CM, Kahn ML. Lymphatic function is required prenatally for lung inflation at birth. J Exp Med. 2014 May 5;211(5):815-26

Janmey PA, Wells RG, Assoian RK, McCulloch CA. From tissue mechanics to transcription factors. Differentiation. 2013 Oct;86(3):112-20

Jiang P, Du W, Yang X. A critical role of glucose-6-phosphate dehydrogenase in TAp73-mediated cell proliferation. Cell Cycle. 2013 Dec 15;12(24):3720-6. doi: 10.4161/cc.27267. Epub 2013 Nov 21.

Jiang YZ, Jiménez JM, Ou K, McCormick ME, Zhang LD, Davies PF. Hemodynamic disturbed flow induces differential DNA methylation of endothelial kruppel-like factor 4 (KLF4) promoter in vitro and in vivo. Circ Res. 2014 Apr 22.

Jones SL, Korobova F, Svitkina T. Axon initial segment cytoskeleton compromises a multiprotein submembranous coat containing sparse actin filaments. J Cell Biol. 2014 Apr 14;205(1):67-81

Joshi RP, Schmidt AM, Das J, Pytel D, Riese MJ, Lester M, Diehl JA, Behrens EM, Kambayashi T, Koretzky GA. The ζ Isoform of Diacylglycerol Kinase Plays a Predominant Role in Regulatory T Cell Development and TCR-Mediated Ras Signaling. Sci Signal. 2013 Nov 26;6(303):ra102. doi: 10.1126/scisignal.2004373.

Kim C, Bergelson JM. Echovirus 7 entry into polarized Caco-2 intestinal epithelila cels involves core components of the autophagy machinery. J Virol. 2013 Oct 23

Kim OV, Litvinov RI, Weisel JW, Alber MS. Structural basis for the nonlinear mechanics of fibrin networks under compression. Biomaterials. 2014 May 16. pii: S0142-9612(14)00454-2

Lee RJ, Foskett JK. Ca+2 signaling and fluid secretion by secretory cells of the airway epithelium. Cell Calcium. 2014 Feb 11. pii: S0143-4160(14)00023-2

Lei Q, Pan XQ, Chang S, Malkowicz SB, Guzzo TJ, Malykhina AP. Response of the human detrusor to stretch is regulated by TREK-1, a two-pore-domain (K2P) mechano-gated potassium channel. J Physiol. 2014 May 6. [Epub ahead of print]

Lian L, Suzuki A, Hayes V, Saha S, Han X, Xu T, Yates JR, Poncz M, Kashina A, Abrams CS. Loss of ATE1-mediated arginylation leads to impaired platelet myosin phosphorylation, clot retraction, and in vivo thrombosis formation. Haematologica. 2013 Nov 29.

Litvinov RI, Yarovoi SV, Rauova L, Barsegov V, Sachais BS, Rux AH, Hinds JL, Arepally GM, Cines DB, Weisel JW. Distinct specificity and single-molecule kinetics of the interaction of pathogenic and non-pathogenic anti-platelet factor 4/heparin antibodies with platelet factor 4. J Biol Chem. 2013 Oct 4

Lu H, Liu J, Liu S, Zeng J, Ding D, Carstens RP, Cong Y, Xu X, Guo W. Exo70 isoform switching upon epithelial-mesenchymal transition mediates cancer cell invasion. Dev Cell. 2013 Dec 9;27(5):560-73. doi: 10.1016

Lu J, Han Z, Liu Y, Liu W, Lee MS, Olson MA, Ruthel G, Freedman BD, Harty RN. A host-oriented inhibitor of Junin Argentine hemorrhagic fever virus egress. J Virol. 2014 May;88(9):4736-43

Maas NL, Singh N, Diehl JA. Generation and characterization of an analog-sensitive PERK allele. Cancer Biol Ther. 2014 May 20;15(8)

Majkut S, Idema T, Swift J, Krieger C, Liu A, Discher DE. Heart-specific stiffening in early embryos parallels matrix and myosin expression to optimize beating. Curr Biol. 2013 Dec 2;23(23):2434-9. doi: 10.1016/j.cub.2013.10.057. Epub 2013 Nov 21.

Mak DO, Vais H, Cheung KH, Foskett JK. Nuclear patch-clamp electrophysiology of Ca2+ channels. Cold Spring Harb Protoc. 2013 Sep 1;2013(9):885-91

Marks MS, Heijnen HF, Raposo G. Lysosome-related organelles: unusual compartments become mainstream. Curr Opin Cell Biol. 2013 Aug;25(4):495-505

Matkar S, Katona BW, Hua X. Harnessing the hidden antitumor power of the MLL-AF4 oncogene to fight leukemia. Cancer Cell. 2014 Apr 14;25(4):411-3

Mendrola JM, Shi F, Park JH, Lemmon MA. Receptor tyrosine kinases with intracellular pseudokinase domains. Biochem Soc Trans. 2013 Aug 1;41(4):1029-36

Moughamian AJ, Osborn GE, Lazarus JE, Maday S, Holzbaur EL. Ordered recruitment or dynactin to the microtubule plus-end is required for eiffcient initiation of retrograde axonal transport. J Neurosci. 2013 Aug 7;33(32):13190-203

Murray JM. HIV treatment as prevention in a developed country setting the current situation and future scenarios of Australia. J Acquir Immune Defic Syndr. 2013 Dec 1;64(4):409-16. doi: 10.1097/QAI.0b013e3182a6b20c.

Naidoo N, Davis JG, Zhu J, Yabumoto M, Singletary K, Brown M, Galante R, Agarwal B, Baur JA. Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism. Aging Cell. 2014 Feb;13(1):131-41

Namba F, Go H, Murphy JA, La P, Yang G, Sengupta S, Fernando AP, Yohannes M, Biswas C, Wehrli SL, Dennery PA. Expression level and subcellular localization of heme oxygenase-1 modulates its cytoprotective properties in response to lung injury: a mouse model. PLoS One. 2014 Mar 5;9(3):e90936

Nelson FE, Hollingworth S, Rome LC, Baylor SM. Intracellular calcium movements during relaxation and recovery of superfast muscle fibers of the toadfish swimbladder. J Gen Physiol. 2014 May;143(5):605-20

Noel J, Wang H, Hong N, Tao JQ, Yu K, Sorokina EM, Debolt K, Heayn M, Rizzo V, Delisser H, Fisher AB, Chatterjee S. PECAM-1 and caveolae form the mechanosensing complex necessary for NOX2 activation and angiogenic signaling with stopped flow in pulmonary endothelium. Am J Physiol Lung Cell Mol Physiol. 2013 Dec;305(11):L805-18. doi: 10.1152/ajplung.00123.2013. Epub 2013 Sep 27.

Panda D, Rose PP, Hanna SL, Gold B, Hopkins KC, Lyde RB, Marks MS, Cherry S. Genome-wide RNAi screen identifies SEC61A and VCP as conserved regulators of Sindbis virus entry. Cell Rep. 2013 Dec 11. pii: S2211-1247(13)00695-5. doi: 10.1016/j.celrep.2013.11.028

Parker ZF, Iyer SS, Wilen CB, Parrish NF, Chikere KC, Lee FH, Didigu CA, Berro R, Klasse PJ, Lee B, Moore JP, Shaw GM, Hahn BH, Doms RW. Transmitted/founder and chronic HIV-q envelope proteins are distinguished by differential utilization of CCR5. J Virol. 2013 Mar;87(5):2401-11

Rawnsley DR, Xiao J, Lee JS, Liu X, Mericko-Ishizuka P, Kumar V, He J, Basu A, Lu M, Lynn FC, Pack M, Gasa R, Kahn ML. The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development. J Biol Chem. 2013 Aug 23;288(34):24429-40

Riese MJ, Wang LC, Moon EK, Joshi RP, Ranganathan A, June CH, Koretzky GA, Albelda SM. Enhanced Effector Responses in Activated CD8+ T Cells Deficient in Diacylglycerol Kinases. Cancer Res. 2013 Jun 15;73(12):3566-77

Rosenblum G, Chen C, Kaur J, Cui X, Zhang H, Asahara H, Chong S, Smilansky Z, Goldman YE, Cooperman BS. Quantifying Elongation Rhythm during Full-Length Protein Synthesis. J Am Chem Soc. 2013 Jul 31;135(30):11322-9

Rubin AI, Seykora JT. Is more hair always better? A single biopsy specimen is preferred for the evaluation of alopecia. J Cutan Pathol. 2013 Oct 7

Shilling D, Müller M, Takano H, Mak DO, Abel T, Coulter DA, Foskett JK. Supression of InsP3 receptor-mediated Ca+2 signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis. J Neurosci. 2014 May 14;34(20):6910-23

Shin JW, Buxboim A, Spinler KR, Swift J, Christian DA, Hunter CA, Léon C, Gachet C, Dingal PC, Ivanovska IL, Rehfeldt F, Chasis JA, Discher DE. Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells. Cell Stem Cell. 2013 Nov 19. pii: S1934-5909(13)00455-4. doi: 10.1016

Shin JW, Spinler KR, Swift J, Chasis JA, Mohandas N, Discher DE. Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18892-7. doi: 10.1073/pnas.1304996110. Epub 2013 Nov 4

Shuman H, Greenberg MJ, Zwolak A, Lin T, Sindelar CV, Dominguez R, Ostap EM. A vertebrate myosin-I structure reveals unique insights into myosin mechanochemical tuning. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2116-21.

Smith JR, Syre PP, Oake SA, Nicholson KJ, Weisshaar CL, Cruz K, Bucki R, Baumann BC, Janmey PA, Winkelstein BA. Salmon and Human Thrombin Differentially Regulate Radicular Pain, Glial-Induced Inflammation and Spinal Neuronal Excitability through Protease-Activated Receptor-1. PLoS One. 2013 Nov 20;8(11):e80006. doi: 10.1371/journal.pone.0080006.

Song D, Li LS, Arsenault PR, Tan Q, Bigham AW, Heaton-Johnson KJ, Master SR, Lee FS. Defective tibetan PHD2 binding to p23 links high altitude adaptation to altered oxygen sensing. J Biol Chem. 2014 Apr 7. [Epub ahead of print]

Srinivasan S, Spear J, Chandran K, Joseph J, Kalyanaraman B, Avadhani NG. Oxidative stress induced mitochondrial protein kinase A mediates cytochrome C oxidase dysfunction. PLoS One. 2013 Oct 10;8(10):e77129. doi: 10.137

Stettler N, Murphy MM, Barraj LM, Smith KM, Ahima RS. Systematic review of clinical studies related to pork intake and metabolic syndrome or its components. Diabetes Metab Syndr Obes. 2013 Sep 25;6:347-357

Syrovatkina V, Fu C, Tran PT. Antagonistic spindle motors and MAPs regulate metaphase spindle length and chromosome segregation. Curr Biol. 2013 Dec 2;23(23):2423-9. doi: 10.1016/j.cub.2013.10.023. Epub 2013 Nov 14.

Sun Z, Feng D, Fang B, Mullican SE, You SH, Lim HW, Everett LJ, Nabel CS, Li Y, Selvakumaran V, Won KJ, Lazar MA. Deacetylase-independnt function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor. Mol Cell. 2013 Nov 19. pii: S1097-2765(13)00788-0. doi: 10.1016/j.molcel.2013.10.022

Swift J, Ivanovska IL, Buxboim A, Harada T, Dingal PC, Pinter J, Pajerowski JD, Spinler KR, Shin JW, Tewari M, Rehfeldt F, Speicher DW, Discher DE. Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation. Science. 2013 Aug 30;341(6149):1240104

Tripepi M, Esquivel R, Wirth R, Pohlschröder M. Haloferax volcanii cells lacking the flagella subunit, FlgA2, are hypermotile. Microbiology. 2013 Aug 29

Tsou RC, Rak KS, Zimmer DJ, Bence KK. Improved metabolic phenotype of hypothalamic PTP1B-deficiency is dependent upon the leptin receptor. Mol Metab. 2014 Jan 19;3(3):301-12

Tu L, Khanna P, Deutsch C. Transmembrane segments form tertiary hairpins in the folding vestibule of the ribosome. J Mol Biol. 2013 Sep 17

Valvezan AJ, Huang J, Lengner CJ, Pack M, Klein PS. Oncongenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapmycin complex 1 (mTORC1) in mice and zebrafish. Dis Model Mech. 2013 Nov 7.

Wang H, Svoronos AA, Boudou T, Sakar MS, Schell JY, Morgan JR, Chen CS, Shenoy VB. Necking and failure of constrained 3D microtissues induced by cellular tension. Proc Natl Acad Sci U S A. 2013 Dec 9.

Wang L, Tran PT. Visualizing single rod-shaped fission yeast vertically in micro-sized holes on agarose pad made by soft lithography. Methods Cell Biol. 2014;120:227-34

Wang J, Han X, Wong CC, Cheng H, Aslanian A, Xu T, Leavis P, Roder H, Hedstrom L, Yates JR 3rd, Kashina A. Arginyltransferase ATE1 catalyzes midchain arginylation of proteins at side chain carboxylates in vivo. Chem Biol. 2014 Mar 20;21(3):331-7

Wang T, Yanger K, Stanger BZ, Cassio D, Bi E. Cytokinesis defines a spatial landmark for hepatocyte polarization and apical lumen formation. J Cell Sci. 2014 Jun 1;127(Pt 11):2483-9

Wannemacher KM, Jiang H, Hess PR, Shin Y, Suzuki-Inoue K, Brass LF. An expanded role for Semaphorin 4D in platelets includes contact-dependent amplifcation of Clec-2 signaling. J Thromb Haemost. 2013 Oct 17. doi: 10.1111/jth.12428

Wells RG. The portal fibroblast: not just a poor man's stellate cell. Gastroenterology. 2014 May 9. pii: S0016-5085(14)00601-5

Wickramasinghe SR, Patel VV. Local innervation and atrial fibrillation. Circulation. 2013 Oct 1;128(14):1566-75

Wong YC, Holzbaur EL. The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation. J Neurosci. 2014 Jan 22;34(4):1293-305

Xiao Y, Nagai Y, Deng G, Ohtani T, Zhu Z, Zhou Z, Zhang H, Ji MQ, Lough JW, Samanta A, Hancock WW, Greene MI. Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60. Cell Rep. 2014 May 14. pii: S2211-1247(14)00323-4

Xu J, Hopkins K, Sabin L, Yasunaga A, Subramanian H, Lamborn I, Gordesky-Gold B, Cherry S. ERK signaling couples nutrient status to antiviral defense in the insect gut. Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):15025-30

Yoon H, Knight SA, Pandey A, Pain J, Zhang Y, Pain D, Dancis A. Frataxin-bypassing Isu1: characterization of the bypass activity in cells and mitochondria. Biochem J. 2014 Apr 1;459(1):71-81

Zhao Y, Liu J, Yang C, Capraro BR, Baumgart T, Bradley RP, Ramakrishnan N, Xu X, Radhakrishnan R, Svitkina TGuo W. Exo70 generates membrane curvature for morphogenesis and cell migration. Dev Cell. 2013 Aug 12;26(3):266-78

Zhang XH, Feng R, Lv M, Jiang Q, Zhu HH, Qing YZ, Bao JL, Huang XJ, Zheng XL. Arsenic trioxide induces apoptosis in B-cell chronic lymphocytic leukemic cells through down-regulation of survivin via the p53-dependent signaling pathway. Leuk Res. 2013 Dec;37(12):1719-25. doi: 10.1016/j.leukres.2013.09.019. Epub 2013 Sep 29

Zhang Y, Morris JP 4th, Yan W, Schofield HK, Gurney A, Simeone DM, Millar SE, Hoey T, Hebrok M, Pasca di Magliano M. Canonical Wnt Signaling Is Required for Pancreatic Carcinogenesis. Cancer Res. 2013 Aug 1;73(15):4909-4922

Zhang Z, Pinto AM, Wan L, Wang W, Berg MG, Oliva I, Singh LN, Dengler C, Wei Z, Dreyfuss G. Dysregulation of synaptogenesis genes antecedes motor neuron pathology in spinral muscular atrophy. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19348-53. doi: 10.1073/pnas.1319280110. Epub 2013 Nov 4

Zou Y, Zwolanek D, Izu Y, Gandhy S, Schreiber G, Brockmann K, Devoto M, Tian Z, Hu Y, Veit G, Meier M, Stetefeld J, Hicks D, Straub V, Voermans NC, Birk DE, Barton ER, Koch M, Bönnemann CG. Recessive and dominant mutations in COL12A1 cause a novel EDS/myopathy overlap syndrome in human and mice. Hum Mol Genet. 2013 Dec 11.