Articles & Spotlights
May 1, 2018
William Quinn, III, David Frederick, Karthikeyani Chellappa, Joe Baur, and their collaborators published in Cell Metab.: Quantitative Analysis of NAD Synthesis-Breakdown Fluxes. Click the title for the full article!
April 24, 2018
Julie Heffler, Ben Prosser, and their collaborators published in Cell Rep.: MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca2+ Stress. Click the title for the full article!
April 13, 2018
Zhongming Ma, Rob Lee, Henry Hoff, Riley Payne, Claire Mitchell, and Kevin Foskett published in Neuron: CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes. Click the title for the full article!
April 3, 2018
Jeff Nirschl Ken Margulies, and colleagues published in PLoS One A deep-learning classifier identifies patients with clinical heart failure using whole-slide images of H&E tissue. Click the title for the full article!
March 7, 2018
Ken Margulies and colleagues published Predicting Long Term Outcome in Patients Treated With Continuous Flow Left Ventricular Assist Device: The Penn-Columbia Risk Score in J. Am. Heart Assoc. Click for the full article!
March 7, 2018
Roberto Dominguez, Erika Holzbaur, Clara Franzini-Armstrong, Mara Olenick, Malgorzata Boczkowska, and In-Gyun Lee published A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity in Nat. Comm. Click for the abstract on PubMed!
March 6, 2018
Joe Baur and colleagues published Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice in Cell Metab. Click for the abstract on PubMed!
March 6, 2018
Joe Baur and colleagues published NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR in Cell Metab. Click for the abstract on PubMed!
March 5, 2018
Paul Janmey and colleagues published Matching material and cellular timescales maximizes cell spreading on viscoelastic substrates in Proc. Natl. Acad. Sci. USA Click for the full on article ahead of print!
March 2, 2018
Shampa Chatterjee and PSOM colleagues published Lung Metabolism and Inflammation during Mechanical Ventilation; An Imaging Approach in Sci. Rep. Click for the full article!
March 1, 2018
Rob Lee and colleagues published Nitric oxide production is stimulated by bitter taste receptors ubiquitously expressed in the sinonasal cavity in J. Am. J. Rhinol. Allergy. Click for the full article!
February 27, 2018
Shampa Chatterjee and PSOM colleagues published Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605) Reduces Asbestos-Induced Cytotoxicity in an Nrf2-Dependent and -Independent Manner in Antioxidants. Click for the abstract on PubMed!
February 23, 2018
Shampa Chatterjee and collaborators published Lung Metabolism and Inflammation during Mechanical Ventilation; An Imaging Approach in Sci Rep.. Click for the full article!
February 21, 2018
Paul Janmey published Glial Tissue Mechanics and Mechanosensing by Glial Cells in Fronteirs in Cellular Neuroscience. Click for the full online article!
February 6, 2018
Mike Ostap, Roberto Dominguez, and Henry Shuman published High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing in PNAS. Click for the full article!
Claire Mitchell and her lab published Robust lysosomal calcium signaling through channel TRPML1 is impaired by lysosomal lipid accumulation in FASEB J. Click for the full article!
January 31, 2018
Anna Kashina and Penn Vet colleagues published Rapid and dynamic arginylation of the leading edge β-actin is required for cell migration in Traffic. Click for the PubMed abstract!
Shampa Chatterjee and two others edited and published the book Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support with Elsevier. Click the title for access!
December 19, 2017
Steve Baylor and collaborators published Small Ca2+ releases enable hour-long high-frequency contractions in midshipman swimbladder muscle in JGP. Click for the full article!
November 25, 2017
Shampa Chatterjee and collaborators published Synthetic Secoisolariciresinol Diglucoside (LGM2605) Protects Human Lung in an Ex Vivo Model of Proton Radiation Damage in Int J Mol. Sci.. Click for the full article!
November 23, 2016
Claire Mitchell and colleagues published in Frontiers in Cellular Neuroscience. Read about the Neuronal Release of Cytokine IL-3 here!
November 14, 2016
Erika Holzbaur published twice with her lab members.
Read Live-cell imaging of retrograde transport initiation in primary neurons with Jeff Nirschl.
Check out Comparative analysis of axonal transport markers in primary mammalian neurons with Eva Klinman.
August 9, 2016
David Frederick, Emanuele Loro, Antonio Davila, Jr, Karthikeyani Chellappa, William Quinn III, James Davis, Teji Khurana, and Joe Baur, published a collaborative effort "Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle" and achieved the cover article in Cell Metabolism, Read the full article here!
September 20, 2017
Chantell Evans, PhD, of the Holzbaur Lab, has been named a Hanna Gray Fellow of the HHMI! Read all about it here!
March 29, 2017
Congratulations to Claire Mitchell for her promotion to full Professor in the Department of Anatomy and Cell Biology!
March 1, 2017
Congratulations to Joe Baur, now Associate Professor of Physiology, for receiving tenure!
September 26, 2016
Congratulations to Yale E. Goldman as the Principal Investigator of a new NSF Science and Technology Center! Read all about it here!
March 18, 2016
Congratulations to award winning trainees in the Holzbaur lab! Read about them here!
March 3, 2016
Foskett lab discovers that cancer cells are addicted to calcium... Read more!
January 8, 2016
Kevin Foskett was quoted in the latest online issue of People Magazine. As the Chief Scientific Advisor for Emily’s Entourage, a non-profit foundation seeking cures for cystic fibrosis, he commented on technologies and efforts underway to accelerate cures for CF pateints with rare mutations. Read the full article here!
December 19, 2015
Congratulations to Jessica Tanis, Ph.D. (Foskett lab) for her recruitment to the faculty at the University of Delaware! Read more
August 27, 2015
Brian Salzberg, PhD has been elected as the 2017 Chair of the Exocytosis and Endocytosis Subgroup of the Biophysical Society.
Congratulations to Shampa Chatterjee, Ph.D. for her promotion to Research Associate Professor of Physiology!
June 18, 2015
Dominguez Lab and PMI members featured in Penn Medicine press for their recent paper in Current Biology. Read more
May 21, 2015
Katya Grishchuk’s Science paper highlighted in the Penn press! Read more
April 24, 2015
Congratulations to the Grishchuk lab who reported in Science on the role of microtubule detyrosination in mitosis. Katya, her lab and collaborators have published a report entitled “Mictotubule detyrosination guides chromosomes during mitosis” that has just appeared in Sciencexpress! Read more
March 5, 2015
Richards Building, Muscle Physiology and Calcium Signaling highlighted in Penn Med News! Read more