J. Kevin Foskett, PhD

Isaac Ott Professor

Chair of Physiology

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From Our Chair


Welcome to the Department of Physiology in the Perelman School of Medicine at the University of Pennsylvania. Our Department is devoted to research, training, and education and strives to push the boundaries of scientific discovery and academic development. The Department’s internationally recognized faculty, in conjunction with post-doctoral fellows, graduate students, and staff, use innovative tools to uncover physical and chemical mechanisms of biological processes. Our frontiers span the molecular to organ level to determine how the human body functions in health and disease.

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Events Calendar


  • On the Road Seminar: Lee Sweeney, PhD

    Thursday, July 31 - 4:00pm-5:00pm

    Richards B404 (map)

  • On The Road Ice Cream Social Reception

    Thursday, July 31 - 5:00pm-6:30pm

    CRB 702 (map)

  • On The Road Seminar: Aron Fisher, MD

    Thursday, August 21 - 4:00pm-5:00pm

    Austrian Auditorium (map)

  • On The Road Reception

    Thursday, August 21 - 5:00pm-6:30pm

    CRB 702 (map)

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Roberto Dominguez, PhD

Professor of Physiology

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Faculty Spotlight


The Dominguez lab focuses on understanding the molecular basis for how protein-protein interaction networks bring together signaling, cytoskeleton regulatory, and membrane scaffolding proteins to accomplish specialized functions such as cell motility, cell morphogenesis and intracellular transport. His lab uses a combination of structural biology (x-ray crystallography, SAXS, FRET) and biophysical (ITC, MALS, SAXS, FRET, TIRF) approaches and collaborative cellular studies.

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Ekaterina Grishchuk, PhD

Assistant Professor of Physiology

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Faculty Spotlight


The Grishchuk lab focuses on the mechanisms of chromosome motions. Dr. Katya Grishchuk’s initial training was in biophysics. She subsequently received a Ph.D. in biological sciences. During her post-doctoral training, she capitalized on her multidisciplinary background to establish long-term collaborations with biophysicists and computer scientists to build a state-of-the-art laser tweezers system, which allowed the first direct measurements of forces produced by the shortening of microtubules (Grishchuk et al., Nature, 2005).

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Contact Physiology


  • 700 Clinical Research Building

  • 415 Curie Boulevard

  • Philadelphia, PA 19104-6085


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