Perelman School of Medicine at the University of Pennsylvania

SANDRA R. BATES-KENNEY, Ph.D.
Research Assistant Professor
of Physiology

Institute for Environmental Medicine
1 John Morgan Building
3620 Hamilton Walk
Philadelphia, PA 19104-6085
batekenn@mail.med.upenn.edu

Phone: (215) 898-9100
Fax: (215) 898-0868

Other Perelman School of Medicine Affiliations
Institute for Environmental Medicine

Degrees
M.S., University of Pennsylvania, 1971
Ph.D., University of Pennsylvania, 1974

Honors
1974-76 Research Fellowship, U.S. Department of Health, Education and Welfare
1983-86 Atherogenesis, Hypertension and Lipid Metabolism Advisory Committee,
National Heart Lung and Blood Institute
1985 NIH Workshop, Arteriosclerosis and Aging (Chairman)

Professional Affiliations
Sigma Xi
American Society of Biochemistry and Molecular Biology
American Heart Association
American Thoracic Society
Fellow, AHA Council on Arteriosclerosis
American Physiological Society

Research Description
Regulation of surfactant metabolism in the lung, with emphasis on cell membrane receptors for surfactant-associated proteins and lung lipid metabolism.

Representative Publications
Bates, S.R., Gonzales, L.W., Tao, J-Q., Rueckert, P., Ballard, P.L., Fisher, A.B.: Recovery of rat type II cell surfactant components during primary cell culture. Am. J. Physiol. Lung Cell. Mol. Physiol. 282:L267-L276, 2002.

Jain, D., Dodia, C., Bates, S.R., Hawgood, S, Poulain F.R., and Fisher A.B. SP-A is necessary for increased clearance of alveolar DPPC with hyperventilation or secretagogues. Am. J. Physiol. Lung Cell. Mol. Physiol. 284:L759-L765, 2003.

Ruckert, P., Bates, S.R., and Fisher, A.B. Role of clathrin- and actin-dependent endocytotic pathways in lung phospholipid uptake. Am. J. Physiol. Lung Cell. Mol. Physiol. 284:L981-L989, 2003.

Bortnick, A.E., Favari, E., Tao, J-Q, Francone, O.L., Reilly, M., Zhang, Y., Rothblat, G.H. and Bates, S.R. Identification and characterization of rodent ABCA1 in isolated type II pneumocytes. . Am. J. Physiol. Lung Cell. Mol. Physiol. 285:L869-L878, 2003.

Bates, S.R., Tao, J-Q, Notarfrancesco, K., DeBolt K, Shuman,H. and Fisher, A.B. Effect of surfactant protein A on granular aneumocyte surfactant secretion in vitro. Am. J. Physiol. Lung Cell. Mol. Physiol. 285:L1055-L1065, 2003.

Gupta N, Manevich Y, Kazi AS, Tao JQ, Fisher AB, Bates SR. Identification and characterization of p63 (CKAP4/ERGIC-63/CLIMP-63), a surfactant protein A binding protein, on type II pneumocytes. Am J Physiol Lung Cell Mol Physiol. Sep;291(3):L436-46, 2006.

Bates SR, Tao JQ, Yu KJ, Borok Z, Crandall ED, Collins HL, Rothblat GH. Expression and biological activity of ABCA1 in alveolar epithelial cells. Am J Respir Cell Mol Biol. 38(3):283-92, 2008

Bates SR, Dodia C, Tao JQ, Fisher AB. Surfactant protein-A plays an important role in lung surfactant clearance: evidence using the surfactant protein-A gene-targeted mouse. Am J Physiol Lung Cell Mol Physiol. 294(2):L325-33, 2008.

Bates SR, Kazi AS, Tao JQ, Yu KJ, Gonder DS, Feinstein SI, Fisher AB. Role of P63 (CKAP4) in binding of surfactant protein-A to type II pneumocytes. Am J Physiol Lung Cell Mol Physiol. 295(4):L658-69, 2008.

Click here for a full list of publications
(searches the National Library of Medicine's PubMed database.)

 
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