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The Pennsylvania Muscle Institute
is an interdisciplinary group of research investigators with a mission to:

  • Discover the mechanisms of muscle function, muscle disease and motile biological systems through innovative and cross-disciplinary research, and to apply these discoveries to new therapies,

  • Develop state-of-the art technologies for the study of muscle and motile systems,

  • Provide education and training in muscle biology and motility to scientists, physicians, and students.

Research is conducted using biophysics, biochemistry, genetics, physiology and ultrastructure to understand: cell migration and intracellular transport; molecular motors; cell division; muscle contraction and development; muscle pathologies and therapies targeted to muscle disease.

The PMI is prominent in technological and methodological development for these investigations especially in advanced light microscopy, structural spectroscopy, nanotechnology, biochemical kinetics, image processing, molecular biology, and viral gene targeting.

For information about the Wellstone Muscular Dystrophy Cooperative Research Center. Click here


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Pennsylvania Muscle Institute
Perelman School of Medicine University of Pennsylvania
Director: E. Michael Ostap, Ph.D.

700A Clinical Research Building Philadelphia, PA 19104-6085 Phone: (215) 573-9758 Fax: (215) 898-2653