Penn Medicine

Education and Training

Cell Migration and Intracellular Transport

This fluorescence micrograph of a migrating kidney epithelial cell shows the localization of fluorescent antibodies that are bound to myosin-I. Myosin-I is a molecular motor that plays an important role in cell structure and membrane dynamics, and it is a key component of the dynamic cytoskeleton. As can be seen in the figure, myosin-I localizes to a region of the cell (the leading edge) that is undergoing rapid changes in shape and size.

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Pennsylvania Muscle Institute
Perelman School of Medicine University of Pennsylvania
Director: E. Michael Ostap, Ph.D.

700A Clinical Research Building Philadelphia, PA 19104-6085 Phone: (215) 573-9758 Fax: (215) 898-2653