Penn Medicine

Education and Training

Chromosome Segregation and Cell Division

This fluorescence micrograph of a Ptk2 cell shows the localization of tubulin (red) and a member of the dynactin-protein-complex, p22 (green), during cytokinesis. Dynactin is a macromolecular complex that is required for activating cytoplasmic dynein-mediated vesicular transport. This figure shows that the dynactin complex is prominently localized within the midbody of the dividing cells (yellow), thus suggesting that dynein/dynactin complexes may have a novel role during cytokinesis.

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Pennsylvania Muscle Institute
Perelman School of Medicine University of Pennsylvania
Director: E. Michael Ostap, Ph.D.

700A Clinical Research Building Philadelphia, PA 19104-6085 Phone: (215) 573-9758 Fax: (215) 898-2653